Highly significant positive impacts on children's mean DDS (treatment effect = 0.7, p < 0.001) and on the share of children reaching MDD (treatment effect = 0.2, p < 0.001) were shown.
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Highly significant PIDAQ reduction was seen after 1 year ( P < 0.001), which was consistent with Erdinc AM,[ 10 ] where authors reported orthodontic treatment significantly affects the QoL in subjects.
The test meal led to a highly significant rise in plasma CCK-LI concentration 20 and 60 min thereafter (main effect of meal: F = 18.46, p<.001, eta 2 = .45) and did not exceed the normal response ( Figure 1 ).
Differences were considered not significant (ns) when p > 0.05, significant (*) when p < 0.05, very significant (**) when p < 0.01 and extremely significant (***) when p < 0.001. or (****) when p < 0.0001.
These values were found to be highly significant by paired t -test ( P < 0.001).
For IC, passive control groups showed a moderate beneficial effect (SMD = 0.53, 95% CI [0.33, 0.73]), while active control groups were associated with a significant negative effect (SMD = −0.69, 95% CI [−1.02, −0.36]), resulting in a highly significant subgroup difference ( p < 0.001).
The correlation analysis of SR and FR emotions showed that SR valence and FR valence had a positive correlation, with ρ (32) = 0.87, p < .001, and so did SR arousal and FR arousal, ρ (32) = 0.40, p = .025 (marginally significant); SR sadness and FR sadness ρ (32) = 0.55, p = .001; SR happiness and FR happiness, ρ (32) = 0.87, p < .001; and SR anger and FR anger, ρ (32) = 0.60, p < .001.
Bartlett's Test of Sphericity is highly significant (χ 2 = 277.646, p < 0.001), confirming that the variables in the study are sufficiently correlated to be grouped into factors.
Results By analyzing and comparing the three waves of the data ( N = 25,939 in the 2008 wave, N = 22,138 in 2013, and N = 19,177 in 2020), an upward trend was observed in the percentages of reporting problems on all five dimensions ( p < 0.001), resulting in a decreasing trend in utility values (2008: 0.948, 2013: 0.942, 2020: 0.939, p < 0.001).
Marital status was highly significant ( p < 0.001).
This difference was highly significant ( p < 0.001), with a large effect size (V = 0.47).
After further division of the entire cohort by age, this difference did not reach statistical significance for patients younger than 80 years (age range, 28–79 years) ( P =0.246, Figure 2C ), but was again highly significant in the group of patients aged 80 years and older (age range, 80–99 years) ( P <0.001, Figure 2D ).
At six months, there was a highly significant difference in the CAL ( p < 0.001).
The difference among the assessment scores of lectures using Blackboard, OHP and PowerPoint was statistically highly significant (P value < 0.001).
Contrasts analysis showed that the effect of l-mequitazine 10 mg alone was highly significant compared to placebo ( p < 0.001).
Results On intergroup comparison, the difference in the antibacterial activity was found to be highly significant ( p < 0.001).
Sleep and Arousals Including condition alone did not significantly improve model fit (χ 2 (3) =0.003, p =0.99) but the inclusion of sleep stage resulted in a highly significant improvement over the null model (χ 2 (2) = 962.46, p <0.001).
The reduction in urinary leakage episodes, improvement in pelvic floor muscle strength and enhancement in quality of life scores were all highly significant (p < 0.001) (Table 5 - see PDF).
Of 12,341 tests, 55.14% (6805) showed significant signals ( P < 0.05), with 34.7% (4281) being highly significant (|Z| > 3, P < 0.001) ( Fig. 4 A).
Results Relative EEG band power A three-way repeated-measures ANCOVA on relative EEG band power—controlling for age and including fixed subject intercepts to account for the non-independence of repeated measures—revealed a highly significant main effect of frequency band ( F (61 833) = 488.15, P < 0.001) but no overall EO versus EC effect ( F (11 833) = 0.00, P = 1.00) or global group difference between controls and TBI patients ( F (11 833) = 0.03, P = 0.87).
For all photochemical parameters, the main effect of dose was highly significant ( p ≤ 0.001), whereas neither sampling time (DAI) nor the Dose × DAI interaction showed significant effects, indicating that photochemical responses remained stable between 12 and 63 DAI.
Significance levels were defined as follows: p > 0.05, not significant (ns); p < 0.05, significant (* ); p < 0.01 , highly significant (**); p < 0.001 , very highly significant (*** ). 5 discs were used for the quantification of each genotype.
We observed highly significant positive correlation between LAS and GLS ( R = 0.804, P < 0.001), moderate positive correlation between LAS and GCS ( R = 0.760, P < 0.001), and moderate negative correlation between LAS and GRS ( R = −0.757, P < 0.001).
Additionally, Bartlett’s test of sphericity was highly significant ( p < 0.001), which further supported the appropriateness of the factor analysis model.
When the effect of patient insurance status was controlled the association remained highly significant ( r = 0.392, n = 202, p = 0.001).