Excerpts

The mean Widespread Pain Index in the post-COVID group was 4.14 ± 2.95 (out of 19 regions) versus 1.37 ± 2.71 in controls, a highly significant difference ( p < 0.001).

Within 90 sec, the fluorescence intensity was continuously declining in the TP and F + TP groups (P<0.001 and P=0.024, respectively), suggesting that Cl − could be accumulated in OCs in these groups; however, the fluorescence intensity in the F group exhibited an increasing trend (P<0.001), suggesting that OCs in the F group did not retain Cl − .

Improvement remained highly significant ( P < 0.001) for dryness, dyspareunia, and burning) at the 6-month follow up.

Determination of TNF-α concentration in skin and colon cancer cell lines In the case of skin cancer and colon cancer cell lines ( Figures 7A, B ), a highly significant ( p <0.001) scaling down in concentration of TNF-α was observed by 1,000 μg/ml of ethanolic extract.

In an M–K trend analysis, we identified an increasing trend of cumulative rCFR for the week first to 17th ( P < 0.001 and tau = 0.93).

Serum dsDNA levels of the participants The serum dsDNA level was significantly higher in the AGA group compared to both the AHU and HC groups, with a highly significant statistical difference ( P < 0.001).

Using data for 159 districts, we found that the association between dry season and wet season incidence was also highly significant (p < 0.001) overall ( Figure 7 , panel B) and stratified by province or year (not shown), although the proportion of the total variation in epidemic magnitude accounted for by dry season incidence was lower (45%).

Adjusted linear mixed model analyses showed a highly significant positive effect of motivation at Baseline (importance, p < .001, readiness, p = .011) and a significant negative effect of positive symptoms at Baseline on changes in levels of physical activity ( p = .016).

The difference between the measurements in the absence and presence of Ag is highly significant ( P < 0.001).

Diagnosis and medical treatment Initial analyses showed a trend over time of an increasing percentage of adolescents who were diagnosed with a form of GD according to the DSM-IV and DSM-5 (OR 1.117, p < 0.001, 95% CI 1.060–1.178).

Thirty-day/in-house mortality rate was also highly significant in the POAF group (7.1% vs. 1.5%; p value < 0.001) (Table 2 ).

However in vitro treatment with 10 nm insulin caused 285.89 % increase in the GIC and was found to be highly significant ( P < 0.001).

The relationship between years of experience and workplace violence was highly significant ( p ≤ 0.001), suggesting that more experienced nurses may have better coping mechanisms or that prolonged exposure to violent environments results in more significant personal and professional consequences over time.

A 2 × 2 repeated measures ANOVA confirmed a highly significant Condition (baseline, operant) × Perceptual Judgment (action, outcome) interaction, F (1, 77) = 58.6, p < .001, .

The difference between the two groups was highly significant (p<0.001, Student’s test, two-tailed, with Microsoft Excel) in terms of the evolution of the sequences, meaning that recent Guangxi CRF08_BC strains were more evolutionarily different from each other, suggesting perhaps that these strains undergo adaption that allows them to infect people in this locality.

The Mantel test indicated a highly significant correlation ( r 2 = 0.734; P <0.001) between the genetic distances and spatial distances of weedy rice populations, indicating that genetic differentiation among weedy rice populations was significantly correlated with their geographical distribution.

There was a highly significant statistical difference in IgE levels between patients suffering from AFS and CRSwNP (p <.001), with AFS cases showing higher IgE levels (mean (SD) IgE level in IU/ml: 820.2 (752.8) vs. 242.1 381.3)).

Traits having very highly significant correlation (***; p -value ≤ 0.001) with GY were HI (0.70), PH (0.58), SER (0.44), BM (0.43), LSL 3 (0.43), FLW (0.40) and LSL 1 (0.40), LSL 2 (0.40), PN (0.36), PL (0.31), FLL (0.29), and GW (0.29); while TN (0.25) had highly significant correlation (**; p -value ≤ 0.01; Additional file 6 : Table S3).

The correlation between the number of activated voxels within those regions and the number of SWEs remained highly significant for the cortex ( r = 0.79, P < 0.001) ( Fig. 5 A , C ) as well as the thalamus ( r = 0.67, P < 0.01) ( Fig. 5 D , F ).

More importantly, the reduction in new vertebral fractures compared with control was highly significant and similar between the two doses (65% and 69% respectively, p < 0.001) ( Figure 2 ).

Results show a highly significant difference between Zhe-Maidong and Chuan-Maidong and Zhe-Maidong and Chuan-Maidong with paclobutrazol (both p < 0.001) and a significant difference between Chuan-Maidong and Chuan-Maidong with paclobutrazol ( p = 0.041).

Predominant CT findings among histopathological subgroups of the study population We defined a highly significant correlation between the histopathological findings and ground-glass opacity and reticular opacity ( P <0.001).

When the values obtained for the six late-firing origins in zone 1 were pooled and their frequency compared with either that of early origins in zone 1 or with a random distribution profile, the enrichment of late origins in the outermost zone was highly significant ( P = 0.001).

Correlation of IDH1/2 mutation with CPEB1 methylation was highly significant (Fisher's two-sided exact test, p < 0.001).

This interaction was highly significant for the normalized jerk (p < 0.001, Table 3 ), that was not mainly affected by type of stimuli (p = 0.489).