Barely Significant

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highly significantp<0.010.2× alphaqualifiedgold
However, the highly significant (p<0.01) inhibition of GST activity was also recorded at the highest concentration (0.012%) of ZnO NPs, while at lower concentrations (0.004% & 0.008%) of ZnO NPs, an insignificant increase of GST activity was observed, thus showing transition phase from active antioxidant defense mechanism (ADM) to exhausted ADM ( Fig 2B ).
a favorable trendp < 0.010.2× alphagold
Cumulative survival at 24 months remained stable (periods 1989–1998, 1999–2001, 2002–2008, 2009–2011, 2012–2015, 2016–2019 were each 72.0%, 72.9%, 77.7%, 83.0%, 84.9%, 83.5%, p < 0.01), while renal survival showed a favorable trend in the most recent periods (there were each 68.7%, 75.4%, 76.7%, 73.4%, 78.2%, 78.4%, p < 0.01).
highly significantP <0.010.2× alphaqualifiedgold
In cultures from 20- to 24-week-old Winnie mice, there was a highly significant increase ( P <0.01) in the production of T H 1 (IL-12p70 and tumor necrosis factor-α), T H 2 (IL-3, IL-5, and IL-9), and T H 17 (IL-17A and IL-12/23p40) cytokines, and the chemokine monocyte chemotactic protein-1, and a less significant increase ( P <0.05) in other T H 1 (IL-1β and IFN-γ) and T H 2 (IL-10 and IL-13) cytokines, and the chemokines, keratinocyte chemoattractant and granulocyte colony-stimulating factor.
highly significantp < 0.010.2× alphaqualifiedgold
In fact, whereas in non-infected BL-30 and BL-41 cells calcium levels raised to 106 +/- 2 nM (n = 4) and 139 +/- 5 nM (n = 3), respectively, in the corresponding EBV-infected cells calcium levels attained 234 +/- 17 nM (n = 4) and 204 +/- 6 nM (n = 3), respectively, corresponding to a highly significant (p < 0.01) increase in infected cells.