Excerpts

FA had a highly significant effect on cell viability, explaining 57% of variance (ANOVA, p < 0.0001), while the effect of cort was negligible (1.7% of variance, p = 0.63).

Although the interaction was not significant, post hoc simple effect analyses confirmed that the aforementioned trend was highly significant in prefrontal cells (simple effect of cycle, F 3, 2244 = 11.3, P < 10 −4 ), with inferior parietal cells showing a similar but more moderate trend ( F 3, 2244 = 3.32, P = 0.02).

As shown in Additional file 2 , overall, a highly significant positive correlation was found between gene and protein expression of TLR8 ( r = 0.86, P < 0.0001).

Importantly, translationally activated mRNAs present higher mean PARS values in the CDS (0.49) than all genes (0.37) and higher than those mRNAs translationally repressed (0.33) or not affected (0.27), with these differences being highly significant ( P ≤ 0.0001) ( Fig. 5 B).

Results ICount analysis After generating calibration curves using both methods, we found that the P -values of the regression lines were highly significant (Y micro = 0.87x micro + 3.02; R 2 = 0.965, P < 0.0001 and Y macro = 0.59x macro + 69.74, R 2 = 0.965, P < 0.0001).

Finally, site had a highly significant effect on flower height above ground level (X 2 = 344.16, df = 2, p <0.0001).

When results were additionally controlled for chronic conditions and health/functional status, obesity no longer significantly predicted higher inpatient utilization ( p = .58); however, orthopedic procedures remained highly significant among obese respondents ( p < .0001).

Further we have observed a decreasing trend in the level of Tregs in children born to both infected and uninfected mother as compared to the cord blood (p <0.0001 for CFA+ve and p < 0.0001 for CFA-ve).

The CaG(Pol/Ag) nanomatrices synthesised by two different methods has shown quite significant ( p < 0.0001) anti-cancer activity in increase concentration dependant manner.

The negative association between the minimal doubling time and the average number of prophages per host genome was highly significant in this much larger data set (Spearman's ρ =−0.36, P <10 −4 ), independently of host genome size ( Supplementary Figure S7 and Supplementary Table S2 ).

Results of multivariate analyses showed highly significant effects of flow [Pillai’s V = 0.579; F(3,255) = 116.9, P<0.0001] and of speed [Pillai’s V = 0.367; F(12,771) = 8.95, P<0.0001].

For the 50 BF 0.99 SNPs, F ST estimates between pairs of colour morphs were highly significant ( p -value < 0.0001) (Additional file 2 : Table S2), with the highest genetic differentiation between TRI and MAR ( F ST = 0.2145), intermediate between TRI and TYP ( F ST = 0.2125) and the lowest between MAR and TYP ( F ST = 0.1787) (Additional file 2 : Table S3).

Highly significant differences were observed among the genotypes ( P < 0.0001) across all traits. β-carotene ranged from 0.028 to 0.763 μg/g, lutein from 0.11 to 4.79 μg/g, and zeaxanthin from 0.05 to 1.69 μg/g, with total carotenoids reaching up to 9.15 μg/g.

The effects of Training Protocol and Alternate Context on discrimination ratios were analyzed using ANOVA, which yielded a highly significant effect of Alternate Context ( F (1,65) = 22.650, P < 0.0001), confirming that generalization between Contexts A and S was stronger than that between Contexts A and RFS.

Effects of v init on a max were statistically highly significant ( F 3, 213 = 1287, P < .0001).

7 A), a remarkable and highly significant increase in NfL levels was observed in the PTX group ( P < 0.0001) and this increase persisted after 2 weeks of follow-up (Fig. 7 B) and until the end of the follow-up period (Fig. 7 C) ( P < 0.0001 and P < 0.05, respectively). 3.7.2.

There was a highly significant negative correlation between the changes in PINP and BMD in lumbar spine and femoral neck from baseline to 12 months in all patients (r(s) = -0.68, P < 0.0001, and -0.45, P < 0.0001, respectively), and in pre- and post-menopausal patients separately.

In profound cases, highly significant positive correlation was observed between TNF and IL-10 (p < 0.0001) while highly significant negative correlation was observed between IL-6 and IL-10 (p < 0.0001) (Table 3 ).

This correction was highly significant, P < 0.0001 ( Table 1 ).

Variation in Cardiac Mortality Risk by Age and Decade of Diagnosis For all cancers combined, a highly significant decreasing trend (2 P <0.0001) with increasing age at cancer diagnosis was shown for both SMRs and AERs for all cardiac disease (Table 3 ).

In the sensitivity analysis excluding single-study agents, the test of moderators remained highly significant (QM(df = 4) = 54.61, p < 0.0001), with moderate residual heterogeneity (τ 2 = 0.19; I 2 = 31%).

One-way ANOVA revealed a highly significant effect of the nanohybrid loading on TPC (F(3,8) = 784.5, p < 0.0001).

The difference in heme levels between the Sham group and the ischemic core region was highly significant (P < 0.0001) ( Fig. 2 d).

The geographic smooth term explained the largest proportion of total variance and was highly significant ( P < 0.0001) in all years.

The difference across the five main classes (CRC, APL, non-advanced adenoma, non-neoplastic and no pathology) was significant ( P < 0.0001; Kruskal–Wallis) and remained highly significant comparing all classes excluding CRC (P < 0.0001; Kruskal–Wallis).