Repeated measures ANOVA followed with Fisher’s PLSD posthoc test showed a highly significant difference between negative and positive controls over time (p<0.0001), but no significant difference between the two negative control pools or the two positive control pools for Libraries I and II, despite the large number of samples (p = 0.1208 and p = 0.2659, respectively).
Excerpts
The genetic indices based solely on the frequency of the allele MGE7 243 and on the homozygous genotype MGE7 243/243 were strongly associated minSAL, and the models were statistically highly significant ( p < .0001).
The correlation between vascularization and the Breslow thickness was highly significant ( p <0.0001).
Parametric Student’s T-test comparisons coupled with Fischer Combined Probability test, show a highly significant difference (combined p < 0.0001) between the Ulva sp. and Cladophora sp. scaffold test groups, for all four cell concentrations, as well as between the scaffolds’ test and control groups.
At the end of the treatment (Day 37), one-way ANOVA revealed a highly significant difference in rotarod performance among the groups ( P < 0.0001).
Three days following sepsis the two models had an inverse correlation that was highly significant (p<0.0001) with an r = −0.284 ( Figure 4C ).
In the small intestine, diabetic females exhibited a highly significant increase in iNOS compared to their controls ( p < 0.0001), while diabetic males showed a more moderate but significant elevation ( p < 0.01).
The number of patients experiencing exacerbations decreased only during treatment with mepolizumab, and in a statistically highly significant manner [odds ratio, 0.019; 95% confidence interval (CI), 0.001–0.320; hazard ratio p < 0.0001].
We found a moderate but highly significant negative correlation between high SMAD1 expression and KEGG Apoptosis pathway inhibition across the ~ 1000 CCLE cell lines ( R = -0.1486, p < 0.0001) (Fig.
The correlation between consistency colour distance score and speeded-congruency accuracy score for genuine synesthetes is non-significant ( r (32) = −.07, p = .35) whereas for the malingerers, the correlation is highly significant ( r (88) = −.73, p < .0001).
Statistically, extremely significant difference was observed between the prewash and postwash at RT sperm DNA fragmentation mean percentage values ( t = 5.169, P < 0.0001), similarly statistically significant difference was observed between the prewash and postwash at 37°C sperm DNA fragmentation mean percentage values ( t = 5.090, P < 0.0001).
This contrasts sharply with the highly significant differences noted in spleen size and splenocyte number ( P < 0.0001) of sTg MTAG mice compared with the wild-type controls.
There was a highly significant correlation between CD68 + and CD163 + TAMs (Spearman’s r > 0.80 for both sites, p < 0.0001), with analogous staining patterns in the examined samples.
A highly significant regression ( R = 0.71, P < 0.0001) was detected between these two variables, justifying the use of ANCOVA.
Although there were highly significant differences in caudate and putaminal SUVR values between the controls and PD patients ( P < 10 -4 for caudate, P < 10 -22 for putamen), there was greater range of overlapping SUVR values derived from the PET-guided method between the two diagnostic groups ( Fig 3 ).
To determine if the effect of FMR4 on cell proliferation is reproducible in other human cell lines we carried out a similar experiment using HeLa cells and found that all three siRNAs against FMR4 also resulted in highly significant decreases in cell proliferation in comparison to control siRNA (P<0.0001) ( Figure 6B ).
pneumonia is (31.33 ± 14.15 years) with a highly significant difference ( p = 0.0001).
The difference between the vaccine and control group at D28 is highly significant ( P <0.0001).
The highly significant interaction ( P < 0.0001) between external osmotic strength and temperature for the condensation phenotype strongly indicates the interdependence of these two factors.
The second validation step performed by MS-qPCR on core biopsies from 131, 59 and 36 patients with histologically diagnosed PCa, BPH and high-grade PIN, respectively, showed highly significant differences in the methylation status of the APC, TACC2, RARB, DGKZ, C5orf4 and HES5 regions between BPH and PCa ( P <0.0001).
The model was highly significant ( p < 0.0001), with an F-value of 32.68, and the lack of fit was non-significant ( p = 0.3150), confirming the model’s adequacy.
Moreover, the results of ANOVA are shown in Tables S3–S6 as the evaluation of the predicted models, which revealed that the models were highly significant ( p < 0.0001 for all), indicating that the models showed a good fit with our experimental data.
For human genes, highly significant differences were found between G1 and G2 (F = 1.29; p <0.0001), G1 and G3 (F = 1.33; p <0.0001), or G1 and G4 exons (F = 1.33; p <0.0001), while none was found between G2 and G3 (F = 1.04; p = 0.4254), G2 and G4 (F = 1.03; p = 0.4285), or G3 and G4 exons (F = 1.00; p = 0.9243).
PFT was the primary source for systematic variation in CR and the difference between PFTs was highly significant (p < 0.0001) for all elements except for Cs (p = 0.14).
Notably, when neutrophils were treated with 0.25, 0.5, 1, and 2 mM calcium crystal suspensions, the addition of CXCL8 at several concentrations triggered a highly significant increase in NETosis (p < 0.0001), compared to calcium crystals alone.