Treatment with TNF-α or C 2 -ceramide increases the release of proteoglycan from bovine articular cartilage An increase in sGAG release from cartilage explants was observed following 24 hours of treatment with 50 ng/ml TNF-α (1.78 ± 0.5; P = 0.06), which was highly significant at 100 ng/ml TNF-α (2.44 ± 0.5; P < 0.001) in comparison with release from control cultures (0.73 ± 0.07) (Fig. 3a ).
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Highly significant differences were also detected (p ≤ 0.001, Table 5 ) between the scoliosis and the spondylolisthesis groups.
Repeated-measures MANOVA results ( Table 6 ) showed a highly significant main effect of time (Wilks’ Lambda = 0.211, F[4, 79] = 74.035, P < 0.001), with a large effect size (partial η 2 = 0.789), indicating substantial overall improvement post-treatment.
For incurred eggs, ANOVA results were highly significant (F(6,28) = 76.65, p < 0.001).
There was a highly significant improvement in FSDS-R scores as a measure for sexual distress ( p < 0.001; see Table 3 ).
Additionally, there was a highly significant linear trend ( p < .001), confirming a linear increase in subjective value with increase in retail price.
Quantitative analysis: For both automatic and manual methods, we found a highly significant difference in all SNc measurements of Vol, C vol , NSI and CNR between PD and HV (p < 0.001 for GLM-ANCOVA and post-hoc t-tests, Fig. 2 ).
Of note, when stratifying the whole cohort by the occurrence of sorafenib maintenance, the difference in OS between CR1 vs CR2/PIF/relapse patients becomes highly significant, p < 0.001.
Differences were considered significant at P < .05 (*) or highly significant at P < .001 (**). 3.
Indeed, the impact of Steap4 overexpression was highly significant for phase 1 (*** p < 0.001) and phase 2 (** p < 0.01), indicating a protective effect against high-dose cytokines.
The difference was highly significant ( t = −29.12, p = 0.001).
Particularly, the Tajima’s D values of BnaFBA1b and BnaFBA8a reached extremely significant levels ( p < 0.001 and p < 0.0001).
Haemoglobin recovery At both sites, a highly significant increase in mean Hb (g/dl) was observed between day 0 and day 28 in the AL arm (p < 0.001) (Fig. 2 ).
[ 26 ] reported a highly significant improvement in the Tinetti Falls Efficacy Scale (TFES) ( p < 0.001), indicating a robust reduction in the perceived fear of falling.
While the mean improvement difference between the experimental and control groups was a non-significant 0.1 points for men (p = 0.89), it was a highly significant 6 points for women (p < 0.001).
the results showed that the survival of Δ pdh strains in RAW264.7 cells was significantly decreased at 4 h, 6 h and 8 h compared with WT and CΔ pdh strains, and the difference was extremely significant ( P < 0.001), while there was no significant difference between WT and CΔ pdh strains ( P > 0.05) ( Figure 7 ).
6 B , red line) was highly significant for both CAMs and OE21 cells (Fisher exact text, p < 0.001 in both cases).
The χ 2 test was highly significant ( P < .001). 3.4.
The interaction term between fractions and total dose was highly significant and its interpretation is best understood by graphical representation of the model’s predicted outcome ( Fig 2D , p <0.001).
Alpha diversity ( Figure 5 ) analysis of bacterial taxon abundance in the three test groups (C, PC and P) indicated a highly significant difference in the Chao1 index ( P < 0.001, ANOVA), with a highly significant difference between the C and PC groups ( P < 0.001) and a significant difference between the C and P group ( P < 0.05).
This difference was highly significant (Δ = −63.87, t = −14.1, p < 1.0 × 10 −3 ), representing the least effective condition in the study and the only one that failed to exceed the 30% reduction threshold.
However, there were also highly significant ( p = 0.001) differences in microbial community composition between rhizosphere and soil ( Figure 2B ).
However, factorability of the correlation matrix was excellent: the Kaiser–Meyer–Olkin (KMO) measure of sampling adequacy was 0.919 (item MSA values all > 0.70 ), and Bartlett's test of sphericity was highly significant ( p < 0.001 ) , confirming that the inter‐item correlations were appropriate for factor analysis.:contentReference [oaicite:1]index = 1.
The percentage of HCV-positive patients was highly significant ( p < .001) in NHL (30/71, 42.3%) while lower percentage was found in HD patients (1/8, 11.1%).
A highly significant range-variance congruency, F (1, 29) = 37.9, p < 0.001, Cohen's d = 1.12, suggests that participants were more accurate when range and variance conveyed consistent information ( M = 75%, SD = 6.3%), compared to the incongruent condition ( M = 67%, SD = 5.5%).