Barely Significant

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highly significantp<0.0010.0× alphaqualifiedgold
Acoustic startle response measured in another cohort of mice (9 controls and 10 mutants aged 9 weeks) showed an altered curve: there was a highly significant interaction between genotype and startle pulse intensity (F (7,11) = 4.153, p<0.001), and Bonferroni posthoc tests revealed a significantly lower response of mutants at maximum dB (p<0.01, Fig. 2F ).
a significant trendP < 0.0010.0× alphagold
Across tertiles of TG/HDL-C ratio, there was a significant trend of higher conventional lipid parameters such as non-HDL-C*, TC/HDL-C ratio*, TG*, HDL-C*, TC**; and non-lipid parameters body-fat* and BMI*** (* P < 0.001, ** P = 0.015, *** P = 0.002).
a positive trendp = 0.0010.0× alphagold
The methodological quality of the publications shows a positive trend over time, as evidenced by a significant positive correlation between methodological scores and the year of publication (r = 0.45, p = 0.001; see Fig. 3 ), but there is still room for improvement, and future efforts should focus on addressing these limitations. 3.3.