“a decreasing trend”

Random-effects meta-regression analyses showed a decreasing trend in seroprevalence with higher income levels (coefficient ( C ) = –1.65 × 10 −6 ; p < 0.001), and HDI ( C = –0.4001; p < 0.001) ( Figs. 3 A,B).

In terms of age, the SOCQ-general, ‘friends’ and ‘work/studies’ showed a decreasing trend (p<0.001), ‘acquaintances’ showed an increasing trend (p<0.001), and ‘family’ did not show differences among age groups (p = 0.333). ‘Social satisfaction’, measured by the VAS, did not show significant changes either by sex (p = 0.217) or by age (p = 0.262).

However, analysis of elevational trends by years revealed two significant opposing linear trends for total, mycorrhizal and saprotrophic biomass; a decreasing trend in 2012 (slope total = −2.19 ± 0.95, P = 0.023; slope sapro = −0.89 ± 0.35, P = 0.013) and an increasing trend in 2013 (slope total = 3.48 ± 0.95, P < 0.001; slope sapro = 0.90 ± 0.35, P = 0.011).

In particular, we observed a decreasing trend of fluoroquinolones use from 2016 to 2018 ( p < 0.001; Figure 4 ).

After 24 h, Western blot analysis showed a decreasing trend in gD protein expression, and quantitative RT-qPCR revealed reduced viral DNA copy numbers in both phases compared to control ( P < 0.001) (Fig. 2 F and G ).

The population aged above 79 showed a decreasing trend with an AAPC of −1.36% (95% CI: −1.97 to −0.75; p < 0.001), while the population aged between 60 and 79 showed an overall stable trend (p for AAPC = 0.413) ( Supplementary Table S3 ).

3GC and fluoroquinolone resistance showed a decreasing trend over the decade ( p < 0·001, p = 0.002, respectively).

According to segmented regression analysis, there was a decreasing trend in the amount of aminoglycoside and quinolone consumption before the intervention ( p < 0.001 for each antibiotic) ( Table 2 ).

The proportion of anterior DR was significantly higher in earlier stages of NPDR, and the proportion showed a decreasing trend from mild to moderate to severe NPDR (Pearson's chi-square test, p < 0.001).

Participants aged 15–34 yr and 35–49 yr showed a decreasing trend ( P <0.001) while those aged 50–64 yr and 65–80 yr showed an increasing trend ( P <0.001) between 2004 and 2013.

Results: Suicide attempts exhibited a decreasing trend before the pandemic, with a monthly decrease of 0.9% ( P <0.001).

During anesthesia, Cdyn showed a decreasing trend ( P < .001) while Raw showed an increasing trend ( P < .001).

Meanwhile, clindamycin use had a decreasing trend of 0.05% (95% CI 0.03%–0.06%, p < 0.001) per year.

Correlation of axillary surgery performance rate with continuous variables In the linear regression analysis of continuous variables, the axillary surgery rate in DCIS demonstrated a decreasing trend with year of surgery in BCS (−0.009; R 2 = 0.287; 95% confidence interval [CI], −0.014 – −0.004; p = 0.001), while it exhibited an increasing pattern with a large tumor size (0.017; R 2 = 0.599; 95% CI, 0.007 – 0.028; p = 0.005).

The mean age showed a decreasing trend, from 60.06 years in Q1 to 57.18 years in Q4 ( P < 0.001).

Creatinine and uric acid levels showed a decreasing trend ( P < 0.001, Table 1 ), while the estimated glomerular filtration rate (eGFR) showed a modest elevation across tertiles ( P = 0.014, Table 1 ).

The pH of the fish cakes was 7.09 in the control group and 6.87–7.04 in the garlic-powder groups, demonstrating a decreasing trend with increasing amounts of garlic powder (P < 0.001).

Regarding perfusion reserve function, both MPRI and MPR showed a decreasing trend with the progression of disease duration (MPRI, P = 0.001; MPR, P = 0.042), with high consistency (r = 0.551, P < 0.001).

During the same period, there was an increasing trend of HPV infection in the proportion of patients under 35 years of age (Z = 4.784, P < 0.001), a decreasing trend among those aged 36 to 64 years (Z=-4.689, P < 0.001), and no significant change in the proportion of patients aged 65 years and older (Z=-0.378, P = 0.705) (Fig. 2 -A).

RM-ANOVA showed a decreasing trend of the groin, leg, and back pain in the EG in the second to sixth hours after the trial (P < 0.001 for each area of pain measured), while in the CG groin, leg and back pain had an increasing trend (P < 0.001 for each area of pain measured) (Fig. 2 , 3 , 4 ).

From 2007 to 2013, there was an increasing trend in the use of norepinephrine (VUI norepinephrine was 0.24 in 2007 and 0.46 in 2013; p < 0.001) and a decreasing trend in the use of phenylephrine (VUI phenylephrine was 0.20 in 2007 and 0.08 in 2013; p < 0.001).

A decreasing trend in NSE was more accurate than a decreasing trend in NFL levels in predicting good outcome (AUC 0.92 [0.85–0.98] versus 0.50 [0.36–0.64], respectively, p < 0.001) (ESM3 - Table S5 ).

For IS, assessing male and female combined, a decreasing trend of -3.84% was determined (CI: 95% [-4.52: -3.16]; p < 0.001).

Duration for spontaneous passage showed a decreasing trend according to stone location (p<0.001).

Moreover, while the annual number of attributable DALYs showed no statistically significant trend ( P > 0.05), the attributable DALYs rate per 100 000 population had a decreasing trend (β = −5.62; P < 0.001).