“a notable trend”

A notable trend in the quinquennial analysis is the increased use of high-fidelity simulations and the shift towards remote OSCEs during the pandemic.

However, there was a notable trend for decreased expression within the liver by Chronic TRF relative to Acute TRF, in line with previous literature.

A wealth of global experience underscores a notable trend among these tumors, characterized by minimal changes in size during the active surveillance period.

The control groups of both varieties (LD_CK and DY_CK) exhibit a good degree of internal clustering, and there is a notable trend of separation between the groups.

Parental education level, ranging from lower to higher, displayed a notable trend in e-cigarette perception score mean = 2.96, 2.86, 2.67, 2.60, 2.46, respectively.

However, a notable trend indicated a potentially better response to immunotherapy in former smokers compared to current and never smokers.

An analysis of the results obtained from the cooper wheel tracker tests revealed a notable trend: as the polymer content in the asphalt mix increases, there is a corresponding enhancement in its resistance to rutting.

As a result of comprehensive analysis, the DPPH radical scavenging activity of the mixture showed a notable trend.

In this study, both groups demonstrated a significant decrease in IOP from baseline, with a notable trend towards better IOP outcomes observed in the Phaco-GSL group.

There was a notable trend observed in adverse events related to toripalimab, particularly regarding immune-mediated hepatic disorders (n = 7, ROR 343.20, PRR 340.56, IC 8.40, EBGM 338.64) and immune-mediated myocarditis (n = 3, ROR 214.68, PRR 213.97, IC 7.74, EBGM 213.22).

OWR primarily impacts EUI and TCP, showing a notable trend regardless of shading type (see Fig 13q – x ).

In a notable trend, Goodswen SJ and colleagues recently released the first guidelines for reverse vaccinology studies that are based on bioinformatics and immunoinformatics techniques in FEMS Microbiology Review in March 2023 ( 27 ), which bodes well for the continued advancement of this promising field.

However, a notable trend emerged: urinary retention occurred in two caudal patients (13.3%) and none in the SMPB group.

From 2018 until 2022, a notable trend shows an increase in malaria cases during the second half of each year.

The Emergence of Dietary Patterns A notable trend observed in the studies included was a shift from focusing on individual nutrients to broader dietary patterns, particularly plant-based and Mediterranean diets, which emerged as the most frequently studied diets.

-epmc yes pmc-license-ref CC BY-NC-ND issue-copyright-statement © BioMed Central Ltd., part of Springer Nature 2025 Introduction Colorectal cancer (CRC) ranks as the third most common cancer globally, and in developing countries, both its incidence and mortality rates are on the rise annually, with a notable trend toward earlier age of onset [ 1 ].

Finally, a notable trend spanning both paradigms is the use of real‐time digital data streams ( n = 12).

The 13 flavonoids with low accumulation in IR1-002 displayed a notable trend in which many had a quercetin scaffold (5/13) and glycosylation at position 3 (R3, 4/13) ( Fig. 1e and f ).

A notable trend is the progression of quantum technology via metamaterials.

Although the influence of working experience on the usage of web-based discussion tools was not statistically significant at the standard p -value threshold of 0.05, the borderline significance ( p = 0.051, df = 138) shows a notable trend.

According to our knowledge, our study presents the first report of postoperative enhancement in twist, GCS, and GRS with a notable trend towards improvement even in severe cases, although statistical significance was not achieved.

Conventional Herbal Application in the Treatment of Pulmonary Diseases A notable trend in medicine is the use of medicinal plants to cure ailments and improve general health [ 32 ].

As these technologies continue to evolve, a notable trend has emerged that decouples the lithium supplementation process from the constraints imposed by cathode materials.

A notable trend that has recently emerged in which researchers seek to elucidate the relationships between specific microbial communities and their associated metabolic outputs through integrative metagenomic and metabolomic approaches.

Recent epidemiological studies document a notable trend toward younger age at clinical onset ( 77 ).