Barely Significant
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a trend toward significance

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In the literature

Although the number of T‐bet + Th1 cells was significantly higher in patients with CXCL9 high and a trend toward significance was detected with the number of CD8 + cytotoxic T cells in all iCCA stages, the difference was not statistically significant when early (stages ≤II) and advanced (stages ≥III) cancer stages were considered separately (Figure 2 E,F).
RNase1 targets specific subsets of tumor-infiltrating immune cells Consistent with the above data based on the t-SNE-guided stratification (Figure 2 ), a conventional hand-gated strategy ( Figure S3 ) showed that RNase1 increased the frequency of the CD4 + T cell subset by greater than two-fold and the CD8 + T cell subset with a trend toward significance (Figure 3 A and 3 B).