“a worrying trend”

5 Average sperm counts have drastically decreased from 113 million/mL in 1940 to 66 million/mL in the 1990s, according to recent research, which is a worrying trend, 6 and decreased by 51.6 % from 1973 to 2018. 7 Male infertility can result from a range of factors including acquired urogenital abnormalities like blocked vas deferens, epididymitis, congenital issues e.g., undescended testes, ejaculatory duct cysts, endocrine disorders, environmental toxins like pesticides, smoking, genetic factors such as CFTR mutations, Klinefelter syndrome, and idiopathic causes.

At the same time a worrying trend is the increase in debt to GDP ratios in many countries in Sub-Saharan Africa that have embraced UHC as a key policy objective.

multocida isolates from pigs were resistant to three or more classes of antibiotics, indicating a worrying trend that could extend to poultry if similar practices continue.

This is a worrying trend especially considering that the lack of physical activity is a common phenomenon in Saudi Arabia, being as high as 79% in the population we studied and 96% in the Saudi Coronary Artery Disease registry. 17 NAFLD has been shown in various studies to be independently associated with type 2 diabetes, low HDL cholesterol, high triglycerides, and insulin resistance. 9 , 13 , 15 , 16 These factors were also reflected in our study.

This is the first report of bla CTX-M-15 in UK river waters and represents a worrying trend as this gene is the most common ESBL in E. coli and Klebsiella spp . causing clinical disease. 4 Novel hosts were isolated across the Gammaproteobacteria, including Citrobacter braakii , A. media and P. fluorescens , none of which has previously been reported as a carrier of bla CTX-M-15 .

Amphibians are also the most threatened among terrestrial vertebrates, with a worrying trend of increased risk of extinction for newly discovered species, due to restricted ranges, small population sizes and impact from human activities 7 .

This is a worrying trend since international research depends on the national research and extension systems for the delivery and dissemination of their technologies and the sustainability of research for development (R-for-D, also often abbreviated as R4D) requires strong national systems.

Assuming the increased mental healthcare expenditure we found among young adults in the Dutch context is linked to poorer mental health in these generations, this is a worrying trend.

Currently diabetes affects almost half a billion people with a worrying trend in the next future [ 2 ].

Antibiotic resistance patterns in our study reveal a worrying trend, with higher resistance rates compared to other international studies.

The study highlights a worrying trend toward a sedentary lifestyle and excessive food consumption, which is potentially intensified by a decrease in physical activity and poor dietary regulation.

Conclusions: Our study highlights a worrying trend in increasing obesity and hypertension, most likely associated with increasingly poor diet and reduced participation in exercises.

The WHO estimated that over 90% of DM cases are Type 2 Diabetes Mellitus (T2DM) and have predicted a worrying trend for T2DM in the future [ 5 ].

Hence, these results which are based largely on 2030 and 2050 pledges for a subset of the world’s countries, already show a worrying trend for reliance on land in national climate mitigation strategies.

The map reveals that southern municipalities (including the islands) dominate the positive trend in the Malmquist index of social progress, while the Mediterranean regions show a worrying trend towards social regress.

Further investigations are warranted to ascertain if the recorded decline represents a stochastic event or a worrying trend.

This is a worrying trend so early on, because the disease is still increasing.

The findings point to a worrying trend of physical inactivity among adults, which increased by about 5% between 2010 and 2022.

This finding highlights a worrying trend in communities with less access to education, as shown in Fig. 2 .

Regarding toilet use, a worrying trend was observed among public school students, with well over fifty-percent reporting open defecation near school premises due to inadequate toilet facilities.

Dengue is showing a worrying trend of progression in Africa.

It is, however, a worrying trend that more recent publications compared to earlier work provide less information necessary for the reproduction, or to push the innovation of phantoms forward.

These observations present a worrying trend of antimicrobial resistance in the East African region.

Traditional publishing houses turning to the dark side? We suggest that there is a worrying trend that practices common among predatory publishers are becoming increasingly common also among traditional publishers.

The 2012 Kenya AIDS Indicator Survey (KAIS) also revealed a worrying trend of many infected male and female youth unaware of their HIV/AIDS status and this is consistent with the global trends [ 44 , 63 ].