There were no significant interaction effects between any of the clusters and time, although the interaction between the NP-cluster and the GP-, CP- and PSOP-clusters on EDI-PSYNOP almost attained significance ( p = .011, power= 66%).
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p<0.06
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However, the difference in serum elafin between Crohn’s disease patients (mean ± SD: 3.749 ± 1.390 ng/mL) and the control group almost attained significance (Z = 1.86; p = 0.06).
Dispensing of phenoxymethylpenicillin, amoxicillin/ampicillin, co-amoxiclav, oral cephalosporins, macrolides and trimethoprim was lower in the intervention practices accepting a workshop compared with those who declined, while dispensing of oral nitrofurantoin and pivmecillinam was higher. Intention-to-treat analyses In the ITT analyses (Table 2 ) there was non-significantly lower total antibiotic dispensing in the intervention practices allocated to receive the workshop compared with controls, which almost attained significance [−2.7%, dispensing rate ratio (DRR) 0.973, 95% CI 0.945–1.001, P = 0.06].
2 ) almost attained significance (F 1,20 = 4.12, p < .06).
Given that, in addition, the interaction between reward presentation and required stepping strategy also almost attained significance for unequal reward combinations ( χ 2 (2) = 5.03, p = 0.08, first step vs. second step: Z = − 0.99, p = 0.32, OR = 0.58, 95% CI [0.20, 1.69], second step vs. third step: Z = − 1.72, p = 0.09, OR = 0.45, 95% CI [0.18, 1.12]), we argue that the effect of the anticipated body state on decision-making was likely effectuated by means of step adaptations (see Fig. 4 C).