“an established trend”

An established trend is that DHP − s are more hydridic when they are functionalized with electron donating groups.

While the expansion of novel multi-indication anti-cancer drugs has become an established trend in the United States and Europe, with many drugs obtaining more supplemental indications within a few years after their initial approval, 17–20 China has started relatively late in this regard.

In the context of sustainable tourism, an established trend in developed countries, cycling tourism offers tourists the opportunity to explore and discover little-known areas that are often located in mountains or areas with different characteristics ( 4 , 5 ).

However, the influence of the entropic torque on the DW motion is an established trend with the DW moving towards the hot edge.

Moreover, the development of synthetic biomaterials with essential biological properties has become an established trend in tissue engineering.

Today, the use of various forms of nanostructured carbon, such as carbon nanotubes (CNTs), fullerenes, graphene, etc., in electrochemical electrodes is an established trend [ 34 , 35 , 36 ].

Core Stakeholder Group Feedback The Current Headline Measure of Domestic Abuse It was put to the participants that the current headline measure of domestic abuse represents an established trend/time series, that the measure has been subject to criticism for de-gendering domestic abuse and not representing adequately the lived experiences of survivors, and that the trend has in any case been interrupted due to the impact of the pandemic on fieldwork for the survey.

A ‘causal’ or ‘likely causal’ category variant was more likely to be discovered in participants who also presented with GDD/ID than those who did not, following an established trend (Stefanski et al. 2021 ).

This is in keeping with the data found in the pan-India study conducted in New Delhi.[ 11 ] However, studies in Mangalore[ 6 ] and Sasaram[ 14 ] concluded that there was a preponderance of male medical students practising self-medication over female medical students, while in coastal South India, females were found to be practising self-medication at a significantly larger scale than males.[ 3 ] It can be concluded here that the practice of self-medication in medical students does not follow an established trend when it comes to gender and that it is a uniformly widespread practice.

We believe this may be attributable to factors such as earlier mortality associated with fragility and the use of Do Not Resuscitate (DNR) orders, the latter of which has an established trend of increased utilization with advancing age [ 29 ].

It is important to be precise about what this evidence does and does not show: a documented decline in open operative exposure is an established trend, whereas a resulting decline in open competence is a reasonable concern that the available data do not directly demonstrate.

Although the management of EA/TEF and DA as isolated lesions is well defined with an established trend of not performing gastrostomy in most patients, the treatment protocol for combined EA/TEF and DA varies in the published literature.

Following an established trend in recent years, NSTEMI are increasing and, given the characteristics of the greater chronic morbidity of these patients, their prognosis is also worse [ 3 , 4 ].

Introduction Due to the recent advances in cardiovascular therapeutics, the growing use of short-term mechanical circulatory support (MCS) devices is now an established trend.

From the year 2000 onwards, reduction with screws had become an established trend.

Overall, there was an established trend for FL-derived cultures to express significantly higher levels of the assayed genes, particularly upon DEX exposure. 3.6.

This motivated us to propose and launch this Special Issue aiming at attracting papers on a wider range of topics related to Sonoprocessing of Materials with a view of becoming an established trend in the Journal and promote links and collaborations between scientists with complementary interests.

However, because only patients with an established trend of lesion expansion are suitable for the trial, a thorough pretrial screening process is necessary.

In comparing the sequence alignments via the alignment matrix, it is evident that the α1-N helix is the region of highest sequence homology between the pilins, an established trend for the T4P from P. aeruginosa , which interestingly appears to cross phylogenies.

As countries become increasingly industrialised, there is an established trend of increasing IBD prevalence in middle- and low-income countries [ 12 ].

More importantly, the unprecedented trend of population ageing, an established trend globally but more significant in the developed world (Appendix B ), will also contribute to a greater susceptibility of populations to RID (Cohen, 2000 ).

However, it is an established trend that women’s ice hockey is getting closer to men’s hockey, and the future of the game will be more of a perfect blend of physical and technical skills.

This study adds a new perspective to an established trend by breaking down the analysis of CPT1A and breast cancer by obesity and menopausal status.

The atomic-oxygen resistance of poly(BAF-oda-fu) fell along an established trend line based on its fluorine content.

An established trend is the continued use of biocatalytic methods, which have successfully replaced the well-established chemical methods to produce enantiopure alcohols.