Barely Significant
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“an increasing trend”

63,972 sentences · 63,972 papers · 107,686 search hits before verification · confirmed specimen

Sighted at

p<0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

pmc-prop-in-epmc yes pmc-license-ref CC BY issue-copyright-statement © BioMed Central Ltd., part of Springer Nature 2024 Background Laryngeal cancer is a common head and neck cancer, with an overall incidence of 2.76 and a prevalence of 14.33 cases/year per 100,000 population worldwide, and showing an increasing trend in recent decades [ 1 ].
414 With an increasing trend, its global prevalence varies from 4.6% to 47.6%. 415 An epidemiological report showed that the annual prevalence of DED in the United States tripled in the course of 7 years from 2005 to 2012. 416 Epidemiological studies have identified some risk factors for the development of DED, such as aging, hormonal changes, autoimmune diseases, low humidity, use of contact lenses, alcohol consumption, pollution, computer use, and certain preservatives in topical drugs, 417 may have contributed to the increased prevalence observed for DED.
Results All disorders reflected an increasing trend throughout the study period: depressive disorders (IRR: 2.44, 95% CI: 2.31–2.59), anxiety disorders (IRR: 2.33, 95% CI: 2.27–2.39), ADHD (IRR: 2.33, 95%CI: 2.17–2.50), and eating disorders (IRR: 3.29, 95% CI: 3.01–3.59).