Discussion In this cohort study consisting of 950 COPD outpatients followed for 3.5 years, we found a borderline significant association between beta-blocker use and increased all-cause mortality.
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p=0.09
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However, after adjusting for confounding variables, only the Madheshi Caste group retains a borderline significant lower risk (AOR: 0.62, 95% CI: 0.375–1.022).
Moreover, there was a borderline significant inverse association between fluoride and HDL–cholesterol levels among female study participants (p linear trend = 0.04), whereas HDL was not associated with fluoride among male participants. 4.
The effect of zinc deficiency on IgG2 in children reported sick without malaria and on IgG3 in children reported sick with malaria was borderline significant ( Table 3 ).
For certain subgroups, significant or borderline significant associations between detection of A. actinomycetemcomitans , F. nucleatum or Archaea and periodontal status are displayed in Tables S1 and S2 in File S1 .
After mutual adjustment, only GRP per capita was found to have a significant association with the health outcomes: there was a borderline significant association between GRP per capita and lower odds of depression symptoms, and a significant association between GRP per capita and lower odds of IADL impairment (Model 6). 3.3.
Association to Telomere Length No significant associations were observed between short tumor RTL and loss of chromosomal regions, although a borderline significant P (0.06) was found for chromosome 3p.
In the current meta-analysis, a borderline significant association between pTERTm and relevant clinical data was observed in overall analysis except for lymphatic analysis.
Notably, RDW showed significantly superior predictive performance at 3 months compared to NLR, and a borderline significant difference compared to PLR.
In the DAS28-remission-Modified dataset (trials categorized as “DMARD-naïve” were omitted in the modified datasets), this trial eligibility criterion showed significant interaction among subgroups and it was borderline significant in the ACR20-Modified dataset.
Yang PW [ 40 ] showed a borderline significant association between rs7813 in GEMIN4 and the prognosis of esophageal squamous cell carcinoma (ESCC).
A borderline significant inverse trend was detected between increasing quartiles of cumulative serum PFOA and risk of currently treated asthma in unlagged analyses (OR for top versus bottom quartile = 0.53, 95% CI = 0.16, 1.69, P trend = 0.27 for continuous log PFOA, P trend = 0.05 for categorical PFOA), and no significant association was detected in analyses with a 10-year lag (OR for top versus bottom quartile = 0.52, 95% CI = 0.09, 2.84, P trend = 0.53 for continuous log PFOA, P trend = 0.17 for categorical PFOA).
In the fully adjusted model, younger children were somewhat more likely to receive a future diagnosis, although the association was borderline significant (HR: 0.97, 95% CI, 0.95-1.00).
We also found that Hispanic/Latino ethnicity and an age of 35 to 49 years had borderline significant associations with higher hesitancy.
The same trends were observed in model B after additional adjustment for axial length; although, the associations were only borderline significant for the temporal and inferotemporal segments.
The effect of deliveries disappeared when evaluating the national programme, although the effect remained borderline significant when restricting to those who had been exposed to the intervention for at least a year [ 14 ].
Moreover, BRCA1 rs12516 CC genotype had a significantly higher BRCA1 protein expression, compared to CT/TT variant genotypes and RAD51 rs7180135 AA genotype had a borderline significant association to a higher expression of RAD51 protein, compared to RAD51 rs7180135 AG/GG variant genotypes.
According to the results of multiple logistic regression, a borderline significant relationship was observed between children’s underlying health status and parental attitudes toward vaccination. the odds ratio comparing the vaccination unacceptance between parents of children with underlying disease to children without underlying disease was approximately 1.77 (95% CI: (0.93, 3.42), P -value = 0.07) indicating that parents of children with underlying disease exhibited more unaccepting attitudes toward vaccination.
Publication year also had a borderline significant mediating effect, which could be potentially explained by treatment advances, i.e., the increased availability of ART as time progressed.
These associations remained borderline significant after testing against different sets of controls. rs9357152 was found to be an eQTL for HLA-DRB1 in HPV-positive cervical tissues (p ANOVA = 0.0009), with the risk allele lowering mRNA levels.
A borderline significant association was found when fatal cases were further restricted to 84 subjects who died out of hospital (OR = 1.84, 95% CI, 1.00-3.40), while the OR was 1.21 (95% CI, 0.75-1.94) for in-hospital deaths.
In these models, psychological distress [Model 5: OR (95% CI) = 1.11 (1.02–1.21)] and physical activity [Model 6: OR (95% CI) = 0.85 (0.77–0.94)] were the only significant covariates, with borderline significant estimates for fruit consumption [Model 6: OR (95% CI) = 0.90 (0.81–1.01)] and socioeconomic disadvantage [Model 7: OR (95% CI) = 1.39 (0.99–1.96)].
This result is borderline significant on the 90% confidence level.
Higher levels of HOMA-IR was associated with EBP/HTN among females and borderline significant among males in this study.
Discussion In this population-based cohort study with almost 20 years of follow-up, we found that baseline type 2 diabetes was associated with a borderline significant increase risk of overall cancer mortality among American Indians from Arizona, Oklahoma, and North/South Dakota.