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extremely significant

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extremely significantp < 0.0010.0× alphaqualified
The correlation analysis demonstrated that Proteobacteria , the first dominant phylum, was positively correlated with almost all the environmental factors, among which SBR and GLU had the highest correlation, all of which reached an extremely significant level ( p < 0.001); POXC and AK ( p < 0.01); and TOC, UA, and CA ( p < 0.05).
extremely significantp < 0.0010.0× alphaqualified
In the progressive phase (days 5–7), multiple indicators presented intergroup differences (all p < 0.05), among which age, PLT, AST, and Cr exhibited extremely significant differences ( p < 0.001); the non-survivor group was characterized by older age, elevated AST and Cr, and reduced PLT.
extremely significantP < 0.0010.0× alphaqualified
The mean pathological evaluation scores of the rSsCLP5-injected healthy rabbit group and allergic history rabbit group were 2.0 points and 1.83 points, respectively, and there was an extremely significant difference compared with the score of the negative control group ( P < 0.001; Additional file 1 : Table S3).
extremely significantp < 0.0010.0× alphaqualified
Statistical analysis showed that the difference between the size of the capsule formed by the vlp1 Δ mutant or the VLP1 overexpression strains and that of the capsule formed by the wild-type strain was extremely significant ( Figure 2 C, p < 0.001 and p < 0.0001, respectively, Student’s t -test), indicating that the Vlp1 proteins played an important role in the formation of the cryptococcal capsules.