“highly significant”

The mean TAS was significantly lower in OC users (0.79 ± 0.19 mmol Trolox equivalent/L) compared to non-users (1.17 ± 0.18 mmol Trolox equivalent/L), with a highly significant difference (z = 9.451; p < 0.001).

All these correlations were highly significant ( p < 0.001).

LMM analysis demonstrated that the main effect of stage was highly significant for all hemodynamic variables, including systolic blood pressure, diastolic blood pressure (DBP), MAP, and CPP (all P < 0.001, Table 4 ), indicating substantial changes in hemodynamic status from the compression stage through to the post-ROSC period.

Notably, DHRS9 and CHGB exhibited higher median values in the experimental group, whereas TNNI1 and DNER showed lower median values, with highly significant differences ( P < .001).

Across sessions, the shift in cue–reward index from adolescent Session 1 to Session 7 was highly significant in ST subjects ( Z = 6.59; p < 0.001, Wilcoxon rank-sum test) but not in GT subjects ( Z = 0.08; p = 0.94).

However, a highly significant difference was found among the monthly average sizes for each sex ( p < 0.001), indicating that the captured population size varied considerably throughout the study period.

Cytometric analysis revealed a highly significant treatment effect ( p < 0.001).

In addition, the time factor had a highly significant effect ( p < 0.001), and a significant main effect of dose was also found ( p < 0.001).

Pairwise differentiation and isolation by distance The overall pairwise differences between populations using ΦST values showed significant ΦST values for 29 of 40 comparisons between eastern and western sites, and most of them were highly significant ( p < 0.001).

In addition, Kruskal-Wallis analysis of historical CL data (2010-2018), summarized in Table 3 , indicated a highly significant difference across regions (χ2 = 18.99, p < 0.001).

Likewise, a marked variation in weight gain was recorded over time, with the day-to-day effect being highly significant ( p < 0.001).

Histomorphometry revealed a highly significant difference ( p < 0.001) in the germinal epithelium thickness between the breeding and non-breeding seasons.

The difference in diploid and aneuploid DNA pattern (the ploidy state) between group 1 and group 2A or group 2B and between group 2A and group 2B and the hyperdiploid aneuploidy and the tumorigenesis was statistically highly significant ( p = 0.001).

The platelet count also showed a highly significant difference ( p = 0.001), with group D having the lowest platelet count (288.83 × 103/mm3), significantly lower than groups A ( p = 0.002), B ( p = 0.009), and C ( p = 0.002).

The relationship between AI Transparency and Employee Trust is highly significant ( r = 0.63; p < 0.001) and the relationship between AI Transparency and Algorithmic Justice is also very strong ( r = 0.72; p < 0.001).

PERMANOVA further revealed highly significant differences in community structure among treatments ( R2 = 0.6858, P = 0.001).

A two-sample t -test confirmed that this difference in the percentage of retained data was highly significant [ t (132) = −27.66, p < 0.001].

The model intercept was negative and highly significant (β = −148.30, SE = 10.64, z = −13.94, p < 0.001), providing the baseline for interpreting the effects of sex, region, and time.

In contrast, transversion frequencies exhibit the opposite trend (Table S5 ): means are significantly higher in tropical taxa in two nucleotide substitution classes (Table S6 ), and differences in the mean rates of accumulation are highly significant ( F = 14.9; df 1 = 1; df 2 = 156; p < 0.001).

In the figure, three stars (***) indicate highly significant overexpression ( P < 0.001), two stars (**) represent moderate significance ( P < 0.01), while a single star (*) denotes relatively lower but statistically significant expression differences ( P < 0.05).

The overall time effect was highly significant ( F = 156.234, p < 0.001).

In the propensity-matched cohort, BMI ≥25.2 kg/m 2 remained a highly significant predictor of complications, with a consistent and robust effect magnitude (adjusted OR 3.35, 95% CI 2.32–4.84, p <0.001).

The interaction between Age and Laughter Type was highly significant as well ( F (2, 174) = 7.70, p < 0.001, partial η 2 = 0.08).

In the contrast between the Positive Control and the Negative Control, a highly significant difference was observed among P-diff levels (p < 0.001), indicating that shell resistance to nutritional challenge varies according to the severity of phosphorus deficiency.

Notably, the test for subgroup differences was highly significant ( P < .001), indicating that the type of intervention substantially moderated the treatment effect, with exosomes showing superior efficacy in reducing serum IL-6 levels compared to whole MSC administration.