“highly significant”

This increase closely resembled the bone resorption marker CTX pattern, with DVP showing a highly significant correlation with CTX ( p = 1.1E −222 ), as illustrated in Figure 5 .

The Kruskal–Wallis test revealed highly significant differences in elevation distributions across species ( H = 1112.88, p < 2 × 10 −212 ), indicating pronounced elevational structuring within the mammalian community.

However, here we found that ToxoNet exhibited a highly significant overlap in protein interactions with both T . brucei (283 common interactions, p = 6.4E-204) and Plasmodium (450 common interactions, p = 0; S6B Fig ).

In the present study, we found a highly significant enrichment of long TRD sequences in RA compared to healthy individuals ( P = 7.91e − 202, Additional file 32 : Fig S7).

Within the brown module, a highly significant correlation was observed between gene significance (GS) and module membership (MM) (correlation coefficient = 0.92, p < 1e − 200) (Fig. 2 D).

This finding was further supported by scatter plots, which demonstrated a highly significant level of connectivity within the turquoise module (cor = 0.77, P < 1e-200, Fig. 3 E).

This trend is, again, present and highly significant in the experimental data ( 52 ) (logistic regression with two-tailed t -test, P = 1.5 × 10 − 195 , n = 7 , 311 ; Fig. 3 D , Right ).

The shift for “No IC” and “Any IC” was also both highly significant ( p = 7.79406e–193 and p = 5.31155e–78, respectively) ( Table S3 ).

Consistent with our previous results, we found a small but highly significant enrichment of dDMPs becoming hypomethylated with cortex development ( n = 28,780 [56.5%], p = 1.61 × 10 −191 ) with the mean effect size being significantly greater for hypomethylated dDMPs than hypermethylated dDMPs (change in DNA methylation [%] per week: hypermethylated dDMPs = 1.03, hypomethylated dDMPs = −1.53, t test p < 1 × 10 −320 , Figure S3 ).

However, the correlation in expression of CD14 and K2 was highly significant (p = 8 x 10 −191 ) compared to that of CD19 and K2 (p = 0.065) at 1 dpi.

A One-Way ANOVA was performed, and the results indicate a highly significant difference between the ligand groups (P-value < 6.6718 × 10 −177 ).

Analysis of CpG sites positively correlated across all tissues revealed ‘nervous system development’ as a highly significant gene ontology (GO) term (P = 2.0 × 10 –171 ).

Using the same Mann–Whitney U test, we find a corrected p -value to be highly significant when comparing LD-18 and HD-18 samples ( p -value = 4.78–153).

In particular, 22 and 17 elements were detected for microRNAs 128 and 138 MREs, respectively, with a highly significant enrichment ( P < 1E −150 , Supplementary Figure 3 and Supplementary Table 3 ).

For five quantitative traits (BMI, DBP, FEV, RHR, and SBP), per-standard deviation (perSD) Beta values for rvPRS showed highly significant associations (max P = 1.21E-149; significance threshold P < 1.26E-04 = 0.05/18/22).

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The precision of this alignment was further quantified, showing a 74.5% overlap between high-risk and tumor cell categories, with McNemar’s test 84 demonstrating a highly significant association ( P = 3.54 × 10 −146 ) (Fig. 5 d), thereby supporting SIDISH’s accuracy in identifying cellular drivers of poor prognosis within their spatial context.

5 G) included 773 genes, which is highly significant ( p = 8.5 × 10− 142 ) with a strong odds ratio of 10.27, indicating that the overlap is about 10 times more frequent than would occur by chance.

In particular, the fluorescence intensity of SUVs preferred by 15GALA-NP increased approximately 2 orders of magnitude compared to free GALA, showing highly significant skewness ( p = 1.12 –141) by comparing the two distributions in a two-sided Welch’s t -test.

The APOE genetic signal remained highly significant in an age-stratified GWAS, on participants with age 60 years or more (OR 1.7, 95% CI 1.63–1.77; P = 2.7 × 10 −141 ; Extended Data Fig. 6 and Supplementary Table 2 ).

This overlap is highly significant by factor of over-representation (4) and P -value ( P < 3.1 e-136).

Figure 7B shows there was a highly significant overlap between the genes affected by cordycepin in the two cell lines ( P < 1.44 × 10 −135 by one‐tailed Fisher's exact test).

Furthermore, the Z-score-based meta-analysis of 1,239 animals in the exploratory cohort revealed a highly significant negative correlation between pH and lactate levels at the individual animal level ( r =–0.62, P =7.54 × 10 –135 ; Figure 1B ).

In fact, the correlation between hearing and deaf regional thickness measurements was highly significant (p = 6.85 × 10 −132 ), demonstrating an R 2 value of 0.98.

Changes to plan shape Throughout the entire handaxe sample, the correlation between tip length and PC1 ( Fig 14 ) is highly significant (r = .642, p = 1.2889E-128), supporting an allometric relationship between handaxe shape and size.