“highly significant”

The difference was highly significant ( P < .001) in all groups ( Figure 2 ).

Their co-occurrence matched random assembly process expectations, but presence of the single ectocommensal species had a highly significant negative effect on recruitment of all burrow-wall commensal species ( P < 0.001), including on its burrow-wall commensal sister species ( P < 0.001).

Seven-Year Follow-Up on Separate Endpoints At 7 years of follow-up ( Table 2 ), the positive association between SERPINA3 and all-cause mortality in the patients as a whole remained highly significant in the univariate analysis ( p < 0.001), and the association with MI was strengthened ( p = 0.008), whereas the association with stroke was no longer present ( p = 0.13).

These proportions are statistically highly significant ( P < 0.001) [ Graph 3 ].

Baseline TIMI flow did not significantly differ between the cases and control patients; there was a highly significant reduction in final TIMI flow and myocardial blush grade (p<0.001).

Kaplan–Meier analysis revealed that the PTEN LOW /CXCR1/2 HIGH cluster was associated with a highly significant reduction in time to BCR [ P < 0.001; hazard ratio (HR) 5.87; Figure 1 C].

Follow-up values Analysis and comparison of the serial laboratory measurements (baseline, 1st, 2nd, 3rd and 6th months after therapy) of patients in both groups revealed that the average platelets, total leucocyte count (TLC) and neutrophils were increased during serial measurements with a highly significant difference ( p < 0.001 respectively).

The best-fit model, selected on the basis of AIC value ( Suppl Table A.1.1 [online only]), was highly significant (F (8,173) = 16.36, P < 0.001), offered reasonable explanatory power (R2 = 0.43), and contained a number of parameters and interaction effects ( Table 3 ).

Soil pH and NH 4 + -N were significantly correlated with bacterial community structure (P < 0.05), with the latter being highly significant (P = 0.001).

INDEL genotype by vernalization treatment interactions was highly significant ( p < .001) and ranked in the same order as previously.

The P -values for colds, pneumonia, diarrhea, fever, vomiting, seizures, rashes, and jaundice were all highly significant ( P = 0.001), supporting that EBF reduces the risk of these infectious diseases.

LMO4 overexpression boosts IL-21-mediated STAT3 signaling to orchestrate a memory-promoting gene regulatory network Among the pathways influenced by both LMO4 and c-Myb manipulation, we also observed a highly significant enrichment of the Reactome pathway R-MMU-1280215, which relates to cytokine signaling ( P < 0.001) and includes several molecules involved in STAT signaling (Fig. 4e , Supplementary Table 5 ).

The survival probability, using Kaplan–Meier (KM) survival curves, shows highly significant differences ( p < 0.001) between control and temperature‐treated groups.

Intra‐individual values calculated with a paired t test were highly significant with P < 0.001, n = 13.

The log likelihood ratio tests revealed that all models were highly significant compared to a single level model (Working Memory: χ 2 = 83.34, p < 0.001; Maths: χ 2 = 131.12, p < 0.001; Reading: χ 2 = 91.03, p < 0.001), indicating a substantial amount of variance attributable at the individual/upper level.

The statistical significance was set at P < 0.05 and statistically highly significant as P < 0.001.

Study-specific prevalence estimates per 100,000 females (95% CI) ranged from 0.0 (0.0, 8.8) to 38.3 (4.6, 138.0), with a highly significant heterogeneity test ( p < 0.001, I 2 = 0.831).

Sperm DNA damage In terms of DNA damage, SCSA analysis revealed a highly significant difference between the sperm isolation procedures, with the FelixTM system isolating sperm cells that had less DNA damage than the DGC isolated population ( p < 0.001 ) (Fig. 4A ).

Inter-strain variation of bacterial and fungi communities based on Bray-Curtis dissimilarity is highly significant [(Supplementary Fig. 2c, d ) PERMANOVA, r = 0.423, P = 0.001 for bacteria; PERMANOVA, r = 0.475, P = 0.001 for fungi], and also between FS and LS [(Supplementary Fig. 2c, d ) PERMANOVA, r = 0.055, P = 0.015 for bacteria; PERMANOVA, r = 0.12, P = 0.001 for fungi)].

However, there still remained a highly significant main effect of SXB on BMI ( F (1,66.799) = 14.916, p < .001). 4 DISCUSSION Our findings (i) confirm that SXB reduces BMI in narcolepsy type 1 patients and (ii) suggest that this is a long‐lasting effect.

New: Figure 2 Kidney function using a) creatinine and b) GFR as surrogates during the follow-up period of 60 months (black HC, grey nESPC) HC = historic cohort, nESPC = new European Senior Program cohort, *** highly significant, p < 0.001 Data are presented as mean ± standard deviation.

The peritoneal membrane was easily permeable for the low-molecular-weight NT-proBNP and correlation with serum levels was highly significant ( r = 0.998, p < 0.001), while dialysate detectability and correlation with plasma concentrations were poor for both GDF-15 ( r = 0.548, p = 0.008) and for the relatively high-molecular-weight cNEP ( r = − 0.194, p = 0.134) (Fig. 1 b).

A comparison of self-perceived oral health status as indicated by a single question and the results of the OHIP-14 revealed a statistically highly significant difference ( p < 0.001).

Serum uPA, fPSA, %fPSA, P2PSA, and PHI levels showed highly significant difference between three studied groups (p ≤ 0.001).

The differences in distributions were highly significant (Kruskal-Wallis-Test, H-Test: p < 0.001).