“highly significant”

Results Inter-observer-correlation ( r ) of DCE-US parameters [time-to-peak (TTP), mean-transit-time (MTT), peak intensity (PI), regional blood volume (RBV), regional blood flow (RBF)] at baseline, day 15, and day 56 was highly significant ( r -range 0.73–0.97, all p < 0.001).

The interaction term potentially allowed the effects of a pharmacologic agent to vary by pulse; because an omnibus likelihood ratio test indicated that interaction term was highly significant ( p < 0.001 for both AUC and Max Change), this term was retained in the final model.

Moderating effect of indecisiveness on rumination and depressive symptoms Utilizing a robust Wald test, the overall model fit was highly significant, R 2 = 0.54, χ 2 (9) = 268.46, p < 0.001.

,[ 22 ] the prevalence of MetS in cases (53%) was statistically very highly significant when compared to controls (17%) ( P < 0.001).

Moreover, a highly significant main effect of “CS-emotion” was found [ F (1, 27) = 65.56; p < 0.001]: the disgust pictures were rated as significantly more unpleasant as compared to the control pictures (see Figure 1 ).

GI scores The GI showed highly significant ( P < 0.001) reduction in gingival inflammation in all the three groups on day 7 as well as on day 14.

( Table 8 ) Over 25% of the variance in impetigo diagnosis was explained by the highly significant (p<0.001) logistic regression model that included multiple demographic and socioeconomic factors.

Laboratory results showed a highly significant (p < 0.001) increase in D-dimer as expected (in PE-patients 3.90 μg/ml [1.60;11.4] compared to 1.40 μg/ml [1.00;2.70] in non-PE-patients, respectively).

It was statistically highly significant (p<0.001) (Figure 4 ).

Correlation equations proved a highly significant correlation of AoR baseline z -scores with losartan dosages, showing that more affected patients received higher up-titrated losartan dosages ( r = 0.407, p < 0.001; Fig. 4 c), thereby keeping AoR progressions constant, independent of baseline AoR z -scores (Fig. 4 d).

The paths leading to eating disorders risk were all significant at the 10% level of significance, but only depression showed a highly significant effect (path coefficient =0.456, p < 0.001).

The Cox-model found a significant influence of water status (p < 0.01) and a highly significant influence of extreme precipitation events (p < 0.001) as determinants for survival.

The mean (± SEM) cAL increase was 11 ± 2 μm at 3 D, 14 ± 2 μm at 6 D, and 26 ± 2 μm at 9 D, with all pairwise comparisons highly significant (all P < 0.001), except the difference between the 3 and 6 D stimuli ( P = 0.48).

As the effect associated with NHS healthcare experiences in the partial model excluding trust is very highly significant (AOR=1.46, 95% CI 1.27 to 1.67, p<0.001), although lower than the effect associated with trust in the partial model excluding NHS healthcare experiences (AOR=2.06, 95% CI 1.8 to 2.36, p<0.001; AOR=2.06, 95% CI 1.8 to 2.36, p<0.001), it seems plausible that the effect of NHS healthcare experiences on uptake may be mediated by trust: a possibility to which we shall return in the exploratory analysis presented in the following subsection.

The inflammatory state of the pulp tissue as reflected by MMP-9/TP levels and NaOCl lavage had a highly significant ( P < 0.001 and P = 0.004, respectively) impact on pulp survival, while mild preoperative discomfort did not.

Note that also when pooling the data of the 2 grid positions, the EM effect in MG is still highly significant (shift = 0.11, P < 0.001; Bootstrap CIs = [0.096 0.126]).

In contrast, the mortality rates of snails in the WPN group, WPN + SHAM group, and WPN + SHAM# groups showed highly significant differences ( P < 0.001) at time points from 6 to 48 h (Additional file 9 : Table S4).

Results Chi-square test revealed significant ( p = 0.001*) and highly significant ( p < 0.001**) differences in diagnostic accuracy regarding the categories “staging” and “grading” in all compared groups when using the diagnostic algorithms (Table 4 ).

KaplanMeier survival times curves showed particularly lower survival probability over time for MMPPI score >8 [ Figure 2 ] and a highly significant difference between the four MMPPI categories (Chi-square statistic = 230, P < 0.001).

The K values decreased further in the postoperative period and the change was highly significant ( P < 0.001) as compared to preoperative value but not significant ( P = 0.059) when compared to intraoperative values. α-angle (which represents the speed of solid clot formation) measured at preoperative, intraoperative, and postoperative time points had mean values of 54.80 ± 5.40 min, 61.94 ± 7.87 min, and 68.57 ± 5.70 min, respectively [ Table 3 ].

However, when the study group was compared with control group, it was highly significant ( P < 0.001).

ANOVA indicated highly significant differences ( p < 0.001) between the A (homozygous resistant), B (homozygous susceptible), and H (heterozygous) groups in all the above assays, indicating their potentiality in marker assisted selection programs.

ANOSIM indicated that differences in the prey spectra between the three species were highly significant at prey family-level (R = 0.784, P < 0.001) but non-significant at the level of order (R = 0.079, P = 0.063).

For the absolute peak area values, the treatment was highly significant (PERMANOVA; pseudo- F = 30.019, p = 0.001), with a component of variation of 4.6922 (square root = 2.1662) and a clear separation between the treatment groups along PCO1, which explained 77.3% of the total variation ( Figure A).

Salinity accounted for the largest proportion of variance, with a sum of squares of 8750, representing 36.8% of the total variation, and exerted a highly significant effect on plant growth (F = 95.4, df = 1,93, p < 0.001).