“highly significant”

We found marginally non-significant support for two-rate models for binary (i.e., presence or absence) conjugation ( P = 0.059; Likelihood Ratio Test) and highly significant support for two-rate models for SAM ( P = 1.58e-07; Supplementary Table 4 ).

Because one individual with Dup7 included in this analysis was treated with growth hormone during childhood, we repeated the analysis testing for association of AAM with 7q11.23 copy number excluding this individual, and the results were largely unchanged and remained highly significant (F = 20.55, η 2 = 0.41, p = 1.6x10 −7 ).

In the early infection group at 15 °C, a highly significant difference was observed between acute and control treatment groups ( p = 1.6 × 10 −7 ), indicating that these groups had distinct effects on mortality.

This difference is highly significant (p = 1.639e-07).

For classification accuracy, the difference was not statistically significant for the paretic arm model ( p = 0.8923) or the combined arms model ( p = 0.0907) but was highly significant for the non-paretic arm model ( p = 1.695 × 10 −7 ).

For each parameter and across the 1000 parameter sets, f del shows a highly significant correlation to S , but one that is only modest in value for some parameters (Spearman’s R = 0.16–0.76, P < 1.7×10 −7 , n = 1000 for all parameters), illustrating that S cannot generally substitute as a measure of f del .

In contrast, defining influenza infection more loosely based on whether a participant reported having flu-like symptoms in the 2019–2020 or 2020–2021 flu seasons (43,956 cases versus 250,673 controls) led to attenuated effect sizes but still highly significant associations: OR = 0.93 and P = 1.7 × 10 −7 for ST6GAL1 , and OR = 0.95 and P = 4.0 × 10 −11 for B3GALT5 (Fig. 2 ).

One-way ANOVA confirmed highly significant differences across doses (F(5,12) = 47.4, p = 1.7 × 10 −7 ), with Tukey’s HSD post-hoc tests revealing robust separation from 2 Gy onward.

Alpha‐power shift can discriminate seizure control subgroups An exploratory LDA with 10‐fold cross‐validation achieved the following performance parameters (mean ± SD [95% CI]): sensitivity of 71.2 ± 3.9% [63.5%, 78.8%], specificity of 79.6 ± 2.2% [75.2%, 83.9%], and AUC of 78.8 ± 1.0% [67.7%, 89.8%], which was highly significant ( z ‐test, P = 1.7 × 10 −7 ).

When we compared our promoter and gene body associated VMGs (271 genes) with that of Harris, we found highly significant overlap of 43 genes ( P = 1.75 × 10 −7 , hypergeometric test).

In the case of Apoc3 , while there was no significant eQTL in liver, there was a highly significant eQTL in adipose tissue ( P = 1.8 × 10 −7 ) (supplemental Table S3).

[ 24 ] is also highly significant (OR = 3.1, P value = 1.8e−7).

We found a highly significant association between the increase in WAT ferritin levels and improvements in insulin sensitivity (FTL, P = 1.81 × 10 −7 ; and FTH1, P = 4 × 10 −7 ) ( Fig. 5, A and B ).

4 and supplementary table S11 , Supplementary Material online), and a simple permutation test shows this observation to be highly significant ( P = 1.9 × 10 −7 ).

Activity An RM-ANOVA revealed highly significant effects for both treatment (F(7, 48) = 9.66; p = 1.95 × 10 −7 ) and the interaction between treatment and time (F(35, 240) = 2.68; p = 5.61 × 10 −6 ) on locomotor activity (LMA), as defined in the Methods section.

The association between MRS and ΔBMI in non-smoking samples is highly significant (n = 1,243, β = 0.045, p = 1.96 x 10 −7 , R 2 = 0.021), albeit with a slightly diminished effect size estimate (empirical p < 0.0061, calculated using 10,000 random samplings of 1,243 FHS samples) compared to association in all samples (n = 1,508, β = 0.055, p = 5.80 x 10 −12 , R 2 = 0.031).

Twelve genes were common to both sets, a highly significant overlap (p = 1.989284e-07 hypergeometric test) (XLS) Click here for additional data file.

However, according to the Spearman rank correlation analysis the expression of IGF-IR and VEGFR-2 was highly positively correlated and statistically highly significant (r = 0.745 and p = 0.0000002) ( Figure 7 ).

However for responses evoked by octopamine and dopamine the correlation is high and highly significant (OA: r s = 0.93, p = 2e-7 [n = 24 responses from 6 oocytes]; DA: r s = 0.97, p = 2e-7 [n = 14 responses from 5 oocytes]).

Simple linear regression revealed a highly significant relationship ( p < 0.0000002) between road kill samples collected and rabid meso-carnivores detected in 2016 (r 2 = 0.86).

Here we found clear differences between non-smokers (2.12 ± 2.07 μg/g creatinine) and smokers (411.37 ± 351.41 μg/g creatinine) that are highly significant (p = 2 × 10 −7 ).

This comparison revealed 56 common genes, representing a highly significant intersection ( Table S2 , P = 2E-07).

Mantoux test results were positive in 75.47% of cases and 24.53% of controls, and the difference was statistically highly significant ( P = 0.0000002).

While rs7041 only had a modest statistical association in our single-SNP GWAS ( p =2.8×10 −4 for antenatal and p =0.01 for cord blood), the results for haplotype association ( Table 4 ) were highly significant (ANOVA p =2.0×10 −7 for antenatal and p =3.0×10 −6 for cord blood).

Analyzing AZGP1 expression as a continuous variable showed a modest, but highly significant inverse correlation between AZGP1 expression and microvessel number ( r = −0.19, p = 2 × 10 −7 , Fig. 7 K).