“highly significant”

In both cases, the calibration curves showed a highly significant linear response over a concentration range spanning two orders of magnitude ( R 2 > 0.99; p value < 10 −5 ; Fig. 3b, c ).

7c ), the VOPP1 / WWOX ratio was a highly significant variable ( p < 0.00001) with a hazard ratio of 3.2 (95% CI 1.9–5.3).

Quantitative assays determined using DNS revealed highly significant differences ( P < 0.00001 with Tukey's HSD at 5 %) for cellulolytic activity among the assayed gut bacterial isolates.

The diverging instrumental effects of DBP and SBP on migraine were also supported by restricting analysis to SNP instruments that were non-significant ( P > 0.05) for one measure but highly significant ( P < 1 × 10 −5 ) for the other (Supplementary Fig. 28 ).

This difference, favoring the untreated patients, is highly significant ( P < 0.00001). 19 Hematomas are not inconsequential. 11 Blood transfusions should rarely be needed for cosmetic surgery patients.

In exploring the subgroup for tensile strength ( Table 4 ) there was a highly significant difference ( P < 0.00001) when nano filler was added to the material, however there was no significant difference when micro fillers were added ( P = 0.74). 3.1.2.

Heterogeneity was negligible (I 2 = 0%), and the test for overall effect was highly significant (Z = 6.16, p < 0.00001) ( Figure 2 ). 3.10.

Hardy–Weinberg equilibrium analysis for rs2904880 revealed highly significant deviation from expected genotype counts ( χ 2 = 161.4, df = 1, p < 0.00001), characterized by a marked heterozygote deficit (observed 271 [22.66%] vs. expected 428.36 [35.82%]) and a reciprocal homozygote excess.

The combined p ‐values obtained for the three hypotheses tested were highly significant ( p < 0.00001) in all cases. 4 DISCUSSION Differences in quantity and quality of the progeny are the most obvious consequences of mating systems and sexual polymorphism, but they are not the only ones.

The results showed a highly significant association between BRCA1 promoter methylation with breast cancer in Asia (OR = 8.78 [95% CI 4.15-18.56, p < 0.00001]).

Similarly, in FA3, the ettringite content showed highly significant increases from 0.03% to 0.24% by aging (Z = 11.24, p < 0.00001).

The paired Wilcoxon test showed highly significant (p < 0.00001) Δ T core ( t ) differences between the time-dependent core temperatures T core ( t ) of the following barrel pairs: artificial zebra versus grey horse, artificial zebra vs. grey cattle and artificial zebra vs. real zebra.

We observed a strong and highly significant overlap of 516 genes (Monte-Carlo empirical P < 10 −5 , normal approximation P < 10 −300 , Additional file 1 : SI Fig.

Statistical result interpretation The one-way ANOVA test revealed a highly significant difference in AgNPs size among the four extract concentrations (F = 98.48, p < 0.00001), indicating that nanoparticle size is strongly influenced by extract concentration.

1 , Supplementary Figure S1 ).The modules were numbered in increasing order from 1 to 30 according to scores of the clustering algorithm 15 (Supplementary Table S1 ); 1 is assigned to the module with the highest score (most densely connected to each other).Next, we assessed whether genes of the clustered terms are significantly interconnected in physical interactions by comparing each of 30 modules with randomly generated networks having the same gene number of the corresponding module and confirmed the highly significant inter-connectivity of them 12 (Supplementary Figure S2 , S3 , p < 0.00001), meaning that their components are not randomly distributed in the interactome.

The strongest structure was among all populations (F ST = 0.098), followed by differentiation among the two ecotypes (F CT = 0.068) and then differentiation among populations within ecotypes (F SC = 0.032), and all were highly significant (p < 10 −5 , Table 5 ).

A paired t-test comparing males and females showed a highly significant difference (t = -12.62, p < 0.00001), indicating that females consistently had higher values compared to males.

There was a highly significant difference in composition by weighted UniFrac analysis ( p < 10 −5 ) (Fig. 3 b).

Higher birefringence was measured in fascicular regions of picrosirius red stained sections relative to matched unstained sections in both tendon types, and these differences were highly significant ( p < 0.00001 for both SDFTs and CDETs).

On these grand-averaged data, a Z-Score computed as the difference between amplitude at the frequency of interest and the mean amplitude of 20 surrounding bins divided by the standard deviation of the 20 surrounding bins (e.g., Rossion et al., 2012 ; Liu-Shuang et al., 2014 ; see also ‘Materials and methods’) was highly significant at electrode Oz (Z = 52.9, p < 0.00001).

Results The values of LV-EDV and LV-ESV measured in 3D-ECHO showed highly significant correlations with CMR (for LV-EDV r = 0.892, p < 0.00001; for LV-ESV r = 0.896, p < 0.00001).

During the Conditioning phase, highly significant (p<0.00001) main group and training day effects were observed and those were sustained over the entire period of Conditioning.

This represents a highly significant association between in planta induced putative effectors and H3K27me3 domains (χ 2 = 45.217, p < 0.00001, S8 Table ).

In the Bodily Pain subscale, both groups demonstrated a highly significant reduction in pain levels postoperatively (IPL: p < 0.00001; HLL: p < 0.00001), underscoring the efficacy of the procedures in improving patient comfort and reducing pain perception.

Phenotypic correlation Highly significant correlations were found between dormancy and GA 3 content in tubers ( P <0.00001).