“highly significant”

Univariate analysis was performed to identify independent predictors of edema and the volume of filler administered was highly significant ( P < 0.00001, Fig. 5 A).

Despite this high level of variability, the overall effect remained highly significant (Z = 5.15, p < 0.00001), indicating the consistent benefit of the combined treatment in accelerating jaundice clearance in neonates ( Figure 5 ). 3.6.3.

For this process we filtered our complete data set by 1-way ANOVA to enrich for mass features with highly significant information ( P < 10 −5 ) in regard to the distinction of seed classes either excluding or including the colour variants of each seed type (Table S2 ; columns AV-AW).

Species Response Curve (SRC) The analysis clearly indicates highly significant differences ( p < 0.00001) for increased population variable (conservation status) in comparison with all other variables due to their maximum frequency as shown in Figure 2A .

The chi-squared test yielded a value of 323.71 with four df, which indicated highly significant heterogeneity ( P < 0.00001), as demonstrated in the forest plot depicted in Figure 3 .

The presence of clustered breakpoints on a per-chromosome basis 13 : chromosomes that had a highly significant non-random distribution of breakpoints with a stringent threshold of P < 10 −5 were considered to be clustered.

A permutation test for a difference in the mean final acuity between these two groups was highly significant ( p < 0.00001).

Studying the individual genes in the 12-gene and 72-gene signatures, revealed that the great majority were overexpressed in the EpCAM + /ITGA6 + /ALDH + population compared to all other luminal/LP populations, a result which was highly significant as assessed using 100,000 Monte-Carlo randomizations (Fig. 6b , P < 1e−5).

We established a baseline frequency of stable aberrations that showed a highly significant curvilinear increase with age (p < 0.00001) that accounted for 70% of the variance among donors.

The mean of the MICs, 0.71 (range: 0.66 to 0.76, n = 166 for each), was highly significant, p < 0.00001 (SD across the 18 MICs = 0.03, 95% CI [0.72, 0.69]).

The difference was highly significant (p < 0.00001).

The strikingly different microsatellite distribution in isolates carrying a resistant or a sensitive haplotype was highly significant (chi-square test P < 0.00001).

Results of the Friedman tests indicated for both MI and ME residuals a highly significant effect [ME: χ ( 3 ) 2 = 146 . 62 , p < 0.00001, W = 0.89; MI: χ ( 3 ) 2 = 135 . 96 , p < 0.00001, W = 0.87].

Between the Non-Gly and the Gly subtypes, we identified 763 highly significant Differentially Expressed (DE) genes (Adj. p < 1E-05), 296 of which over-expressed in Gly subtype and 466 over-expressed in the Non-Gly tumors ( Figure 2A and Supplementary Table 3 ).

Among the top most highly significant pathways ( P < 1.0 × 10 − 5 ) included the pathways involved in MSP-RON, PDGF, molecular mechanisms of cancer, STAT3, prostate cancer, P53, MYC mediated apoptosis, IGF-1, NF-kB, Androgen biosynthesis, PTEN and IL-6 signaling pathways (Fig. 5 ).

A total of 21 children with PSTC and 518 children with migraine showed that drawings had similar features except one-third (28.6%) with PSTC depicted diplopia which was highly significant ( P = 0.00001).

Results : Analysis of spatial overlap between histo-PET and PSMA PET revealed highly significant correlations (p < 10 -5 ) in nine patients and moderate to high coefficients of determination (R2) from 42 to 82 % with an average of 60 ± 14 % in eight patients (in one patient R 2 = 7 %).

Pooled data from 13 distinct datasets (10 unique studies), including 415 FGR cases and 561 controls, demonstrated a marked and highly significant prolongation of left ventricular isovolumetric relaxation time (LVIRT) in FGR fetuses compared with controls (SMD, 2.48 (95% CI, 1.55–3.41); P < 0.00001; I 2 = 97%) (Figure 3d ).

Chlorophyta and Toxoplasma seem to have a significant positive influence on each other ( P < .01), whereas Dictyostelium and Plasmodium seem to have a highly significant positive influence on each other ( P < 10 −5 ).

Most babies (66/74, 89%) experienced a fall in their z -score between stoma formation and reversal, and this growth failure was highly significant ( P < 0.00001, paired Wilcoxon signed-rank analysis).

Nevertheless, a highly significant correlation (Pearson’s correlation coefficient R = 0.968; p < 0.00001) is observed between the frequency of usage of an ataxin-3 amino acid site as a binding site in the two datasets.

The test for subgroup differences confirmed a highly significant difference between the results derived from these two study designs (I2 = 97.4%, p < 0.00001).

The overall pooled analysis demonstrated a highly significant effect, indicating strong evidence for a reduction in 24-hour ambulatory SBP (Z=15.33; p-value <0.00001).

There was very highly significant difference in the marital status of the two groups of study p=0.00001; HIV+ve had more divorcees and widows than HIV-ve (8.6% vs 1.9%), (25.7% vs3.8%) respectively and 88.9% (n=24/27) of the HIV+ve widows testified that their husbands died of HIV infections.

This difference between the juvenile and adult volumes was highly significant ( P < 10 −5 , unpaired t test, t = 7.9, d.f. = 14, comparing trace volumes of juveniles with trace volumes of non-manipulated adult birds with n ≥ 6 HVC X /bird).