“highly significant”

This was highly significant with a P = 0.00001.

Assessment of aCL Presence by Meta-Analysis Presence of aCL in dementia patients was highly significant compared to controls (OR: 4.94, 95% CI: 2.66–9.16, p < 0.00001; I 2 = 32%, p = 0.16) ( Figure 2 ). aCL was present in 32.80% of dementia patients and 9.50% in controls corresponding to 3.45 times higher probability to present with dementia than controls.

In addition, disease duration correlated highly significant (p<0.00001) with the mean longitudinal FA changes in all tract systems.

The excess of transition paths is highly significant by a binomial test ( P < 10 − 5 ; here and below, we do not distinguish values of P below 10 − 5 ).

Similarly, the liraglutide versus placebo/standard treatment subgroup (Figure 4 ) showed a highly significant reduction in BMI (MD: −1.75 kg/m2; 95% CI: −2.38 to −1.12; p < 0.00001), again with no heterogeneity (I2 = 0%), reinforcing the reliability of liraglutide’s effect in weight reduction.

The cumulative occupational exposure Occup_PAHs was highly significant ( p = 0.00001) in coke-oven workers compared to control subjects, for whom it was always zero, as well as the urinary excretion of 1-pyrenol ( p = 0.00001).

The depicted IBD segment in Figure 3 has a highly significant IBD score ( P -value < 1E-5).

Variants were thus discarded if: (i) UCSC alignability ≠ 1 (100bp window size); (ii) variant within 10 bps of a simple repeat region; (iii) highly significant deviation from Hardy-Weinberg equilibrium (HWE) in cases or controls ( P <10 −5 ); (iv) no call rate significantly different between case-samples and control-samples ( P <10 −5 ); (v) no call rate across either case or control samples >0.03.

However, year was highly significant ( P < 0.00001), while PI x year interaction was not significant ( P < 0.623).

Subgroup differences were highly significant (Chi 2 = 754.79, df = 5, p < 0.00001; I 2 = 99.3%) ( Figure 5 ). 3.6.

Peripheral calcifications showed highly significant differences between subtypes ( p < 0.00001).

The Fst values were relatively high and reached highly significant levels (p < 10 −5 ) between populations from Tak (all collection periods) and Yala-Narathiwat (21.75%), and between Ubon Ratchathani and Yala-Narathiwat (19.44%), implying genetic differentiation or limited gene flow between these endemic areas.

Despite this heterogeneity, the overall effect size is highly significant ( Z = 30.91, p < .00001).

There was a highly significant association between age and attitude (X 2 =33.3, p=0.00001).

This analysis focused on the remaining three high-quality RCTs (n = 217), revealing strengthened evidence for topical CCBs: the odds ratio for unhealed fissures increased to 3.12 (95% CI = 1.78–5.47, p < 0.0001), while the previously nonsignificant difference in side effects became highly significant (OR = 13.16, 95% CI = 5.05–34.3, p < 0.00001) with resolved heterogeneity (I 2 = 0%).

The correlation between various stages of OSMF with SOD (per/ml) and MDA (nmol/dl) by Spearman's rank correlation method indicated a significant ( P = 0.0010) moderate inverse relationship between various grades of OSMF with SOD as Spearman R (r s ) was 0.5700 and a highly significant ( P = 0.00001) direct strong relationship between various grades of OSMF with MDA as Spearman R (r s ) was 0.6725 [ Table 4 ].

In fluency [ 17 , 18 , 21 , 41 , 77 ], there was a highly significant deficit in SZ (Hedge’s g = −2.03, df = 4, p < 0.00001, CI = [−2.82, −1.24]), but with large heterogeneity within results (84%) ( Figure 2 (2.6)).

This test showed a highly significant size difference between the spermathecae within a female, suggesting that across timepoints, there is one smaller and one larger spermatheca ( P < 0.00001).

The results showed a highly significant association between BRCA1 promoter methylation with breast cancer in Asia (OR = 8.78 [95% CI 4.15-18.56, p < 0.00001]).

The difference was highly significant (p < 0.00001).

We chose a highly significant setting ( L = 10 kb, N = 3, and h n ≥ 2; P < 10 −5 ) that both allowed for extending clusters over genes potentially missing from the expression array and assured that a cluster was not solely formed by a single set of duplicated genes (since h n > 1) (Figure 1A and B ).

6b and 6f ) is highly significant ( p = 10 −5 ).

The chi-squared test yielded a value of 323.71 with four df, which indicated highly significant heterogeneity ( P < 0.00001), as demonstrated in the forest plot depicted in Figure 3 .

Although highly significant ( p < 0.00001), the result indicates that the assessment of alertness may be quite variable.

In terms of knowledge regarding flossing, 88% dental and 64% medical students had heard about flossing, and the difference was highly significant ( P =0.00001).