“highly significant”

Principal component analysis (PCA) further confirmed distinct microbial community structures between groups, The PERMANOVA analysis revealed a highly significant difference between the two groups ( p = 0.00001) ( Fig. 1C ).

Higher birefringence was measured in fascicular regions of picrosirius red stained sections relative to matched unstained sections in both tendon types, and these differences were highly significant ( p < 0.00001 for both SDFTs and CDETs).

1 , Supplementary Figure S1 ).The modules were numbered in increasing order from 1 to 30 according to scores of the clustering algorithm 15 (Supplementary Table S1 ); 1 is assigned to the module with the highest score (most densely connected to each other).Next, we assessed whether genes of the clustered terms are significantly interconnected in physical interactions by comparing each of 30 modules with randomly generated networks having the same gene number of the corresponding module and confirmed the highly significant inter-connectivity of them 12 (Supplementary Figure S2 , S3 , p < 0.00001), meaning that their components are not randomly distributed in the interactome.

A sensitivity analysis for hematocrit revealed a highly significant increase (MD = 2.15; 95% CI = 1.86–2.44; p < 0.00001).

4 A2 ) showed that the suppression is highly significant during the cue period (Z^ = −7.74, P < 0.00001).

In fathers, the correlations were as follows (all highly significant at p <0.00001): Warmth–Protectiveness +0.36 Warmth–Authoritarianism −0.50 and Protectiveness–Authoritarianism −0.23.

6b and 6f ) is highly significant ( p = 10 −5 ).

A linear regression model between vehicle occupants’ death rate and seatbelt noncompliance in our published data was highly significant ( P <.00001) ( Figure 1 ).

Similarly, in FA3, the ettringite content showed highly significant increases from 0.03% to 0.24% by aging (Z = 11.24, p < 0.00001).

An initial Pearson correlation analysis indicated a highly significant association with Nonpareil diversity and pH ( R = 0.51, p < 1 × 10 −5 ), along with weaker correlations to several other parameters.

For example, the correlation in K s values between the rat-mouse and human-dog lineages is highly significant (Spearman ρ = 0.646, permutation test P -value < 0.00001), and the correlation between the rat-mouse and elephant-tenrec lineages is similar (ρ = 0.671, P -value < 0.00001).

All eligible cases (1,300 cases) Univariate analysis of all cases with complete Mammostrat ® data irrespective of ER status, nodal status or treatment showed a highly significant association between Mammostrat ® score and DRFS (Figure 2b ), between score and RFS (Figure S1D in Additional file 1 ), and between score and OS (all P < 0.00001; Figure S2D in Additional file 1 ).

The contrast for the 2-back to the 0-back condition for RVE (Figure 4 ) shows widespread and highly significant ( p < 10 −5 ) increases in entropy throughout the brain.

There was a statistically highly significant ( P < .00001) association between low serum zinc levels and WHC grades of HE.

The test for overall effect showed a highly significant result ( Z = 4.74; p < 0.00001), indicating that fever was significantly more likely in individuals receiving VLA15 than those receiving placebo.

Among the top most highly significant pathways ( P < 1.0 × 10 − 5 ) included the pathways involved in MSP-RON, PDGF, molecular mechanisms of cancer, STAT3, prostate cancer, P53, MYC mediated apoptosis, IGF-1, NF-kB, Androgen biosynthesis, PTEN and IL-6 signaling pathways (Fig. 5 ).

The difference between the number of reading mistakes before and after the training session was highly significant (Wicoxon Test: p < 0.00001).

For this process we filtered our complete data set by 1-way ANOVA to enrich for mass features with highly significant information ( P < 10 −5 ) in regard to the distinction of seed classes either excluding or including the colour variants of each seed type (Table S2 ; columns AV-AW).

When the blind evaluator rated photos, there was a slightly smaller but still highly significant decrease in score (−1.1) from day 0 to day 360, t(36) = −10.712, p < .00001] with no significant decrease in effect from day 60 to day 360 in most patients as can be shown in Figures 2 – 4 below, with the minority of patients having minimal regression, Figures 5 – 7 .

Seventy markers were excluded from the following analysis, as they showed highly significant departure from Hardy Weinberg equilibrium (P<10 −5 ), obtaining 5,192 markers for the following analysis.

The degree of co-occupancy of these 2 TFs was highly significant ( p < 1 × 10 −5 ; based on permutation tests, see Material and methods , Fig 3D ).

Heterogeneity analysis revealed highly significant heterogeneity ( p < 0.00001, I 2 = 88%), thus a random effects model was used for statistical analysis, and a subgroup analysis was performed according to the trial cycle.

For example, if one gene is repressed by 1.8-fold, the statistical significance may not be very high, but if all 78 cRPGs are repressed to a similar degree with an average of 1.8-fold, 1.8-fold becomes highly significant (P-value < 0.00001 when compared to background genes).

The positive relationship between φ and geographical distance was statistically highly significant (Mantel test, 100000 randomisations, r = 0.375, P = 0.00001), also when corrected for beetle phenotype (Partial Mantel test, 100000 randomisations, r = 0.379, P = 0.00001; see Materials and Methods for comments regarding the value of r of the Mantel test).

Meanwhile, the triple interaction between OV, dwell-time advantage, and TMS condition remained highly significant ( β = –0.710, CI = [–1.019,–0.401], p = 10 –5 ).