For the toy example, a highly significant result was obtained in step 1 (p-value = 0), thus, we proceeded with the grid search (Fig. 2b ) showing that the most frequently returned and therefore selected K -value is 2.
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Furthermore, a meta-analysis containing a total cohort of 1010 patients showed a highly significant association between prolonged PWD and AF recurrence after radiofrequency ablation (Z = 14.20, p < 0.000) [ 38 ].
In the case of women that smoked, high associations were observed for anti-L1-16 and -18 antibodies (OR = 5.30 and 4.84, respectively), and those were highly significant ( p = 0.000 and 0.001, respectively) ( Table 2 ).
Additionally, a highly significant difference ( P = 0.0000) was noted between Chimer_Tv and Chimer_PanTryp-1 ( Figure 6 ).
This difference in CES-D scores between men who reported non-fatal suicidal behaviour and those who did not was highly significant ( p < .000).
This estimate is highly significant ( p -value= 0.00) and carries huge precision as indicated by the width of 95% CIs (2.68 to 2.93).
The entire table also indicates a highly significant and positive ( p = 0.000, T b = 0.458) association between social inclusion and participation in decision making for both genders.
The PHQ9 depression score was higher in sleepy subjects with SES ≥ 11 compared to non-sleepless subjects; the difference being very highly significant (PHQ9=11.97 ± 4.99 and 6.54 ± 5.27 respectively; p=0.0000).
One study 35 suggests that no access to running water is a strong and highly significant predictor of both RF development after ST (OR 12.30 [95% CI 4.66 to 32.49], p<0.000 01) and RHD development after ST (OR 4.26 [95% CI 1.98 to 9.15], p=0.0002).
CMT CMT showed no statistically significant differences between the 3 groups throughout the follow-up period (P-value= 0.276, 0.354, and 0.464 at 1 month, 3 months, and 6 months respectively) ( Table 5 ). The change of CMT ( Table 6 ) was highly significant in the 3 groups (P-value= 0, 0.001, and 0 in groups I, II, and III respectively) throughout the follow-up period ( Figures 5 , 6 and 7 ).
The F-statistic of the model is highly significant ( p < 0.000 with 18; 5501 degrees of freedom), meaning there is a significant relationship between expected household consumption and the explanatory variables.
Paired statistical testing confirmed that the increase was highly significant, with both the paired t-test and Wilcoxon signed-rank test yielding p ≈ 0 .
Populations in Group II exhibited highly significant differentiation ( G st = 0.1111, p-value<0.0000).
In all four research areas, only the dependencies on the variables of the age of the respondents and their length of service turned out to be statistically highly significant ( p ≤ 0.000).
A highly significant difference (Figure 9a ) was measured between postprandial blood sugar levels after consuming both control and intervention recipes ( p = .000).
The cells of the clonal line showed a highly significant suppression to NK sensitivity, P < 0 - 0 1.
The comparison between the reversible and irreversible clauses total scores showed a highly significant difference between TD and ASD children in the comprehension of reversible clauses ( p = 0.000), but not in irreversible clauses ( p = 0.834). 4.
Also, a highly significant improvement occurred to the TAPSE at 3 months (15.45 ± 3.21 versus 17.09 ± 4.17 mm p = 0.00) (see Table 5 ).
Analysis of variance revealed highly significant differences among the groups ( F = 15.89, p = 0.00).
On the other hand, male participants were better in practices (0.001), as illustrated in Table 5 . With regard to college type, it was shown that UCM participants were significantly better than those from UCP only in terms of knowledge ( p = 0.042); however, no significant differences were found in terms of attitudes and practices in Table 6 . Concerning the educational levels of the participants, no significant mean difference was seen in terms of KAP among either the UCP or the UCM participants ( p > 0.05), as found in Table 7 . Table 8 illustrates that the model is highly significant (F = 5.091, p = 0.000).
B16BL6 injections, a mean of 227 + 27 surface tumours were seen in 12 pairs of lungs compared with 286 + 31 total tu- mours, corresponding to 113 + 11%. Although in both tumours the total lung counts were higher than the surface counts, linear-regression analyses between them shows highly significant (P = 000 1) correlation coefficients, and analysis of variance between surface and total copnts fails to reveal significant differences (B16F1O, 0-2>P>0-1; B16BL6, P>0 2).
On the correlation of MMP-9 expression with histological grades of OSCC, we observed MMP-9 expression gradually increased as the tumor progressed from Grade I to Grade II to Grade III and was also found to be statistically highly significant ( P = 0.00) [ Table 6 ].
3.2 Correlation between the number of joints with US synovitis and different clinical parameters (at follow up) At follow up the number of joints with US synovitis had positive highly significant correlation with the number of swollen joints (p=0.000**), number of tender joints (p=0.000**), number of joints with clinical synovitis (p=0.000**), number of joints with LROM (p=0.006**), Ritchie AI (p=0.000**) and duration of morning stiffness (p=0.002**).
This allowed us to assess whether the module overlap graph had significant community structure; the results were highly significant (permuted p = 0; see Additional file 10 for permutation test details).
The ANOVA results for the Flexural Failure Load ( Y 1 ) indicated that the overall model is highly significant ( p -value = 0).