“highly significant”

RT-qPCR analysis showed that when HOTTIP was interfered with, the expression level of miR-216a-5p exhibited a highly significant upward trend ( P < 0.0001, Fig. 2G ).

The quadratic terms (A 2 , B 2 , C 2 , D 2 ) and interaction terms (AB, AC, BD, CD) were highly significant ( p < 0.0001), while BC was significant at the p < 0.01 level ( Table 5 ).

Such models were highly significant (p < 0.0001) for determining TPC, TFC, ABTS, OH, and DPPH.

A significant decrease was found for the 4 Gy (p<0.001) and 8 Gy (p<0.05) irradiation groups at 4 h post-irradiation ( Figure 2C ), and highly significant changes across the dose range of 2–8 Gy (p<0.0001) were found at 24 h post-irradiation ( Figure 2D ).

As shown in Figure 3 , this resulted in a highly significant increase in performance (bootstrap test resulting in p<0.0001 for all tested metrics).

Spearman’s correlation analysis revealed a highly significant association between the WOMAC total score and the CSI score (rho = 0.791, p < 0.0001), the PDQ score (rho = 0.766, p < 0.0001), and the PCS score (rho = 0.536, p < 0.0001) ( Table 2 ) ( Figure 3 ). 3.3.

The mean body mass ± SE of Euclea small and large caterpillars was 71.3±4.4 mg and 253.9±13.1 mg respectively, a highly significant difference (t = 13.20, df = 29.46, P <0.0001).

Moreover, our results showed that the overall average resistance of Salmonella isolated from M-hatcheries was higher than that of L-hatcheries ( p = 0.0013), while statistical analysis performed by using two-way ordinary ANOVA, showed that the difference in resistance to the individual antimicrobial was statistically highly significant ( p < 0.0001) ( Figure 3 ).

Plant height of the 55 genotypes was also highly significant (P<0.0001), ranging from 33-100 cm.

Despite a relatively narrow sampling interval (see methods), we were able to detect a highly significant dependence of sampling time on participant’s MSF sc chronotype ( Supplementary Figure S1A , Pearson’s correlation r = 0.17, p < 0.0001).

The ANOVA results indicate that the fitted quadratic model is highly significant, with a model F‐value of 55.56 and a p value < 0.0001, which implies that the model is highly suitable for describing the relationship between the independent variables and the TPC yield.

Furthermore, the compound induced a highly significant (P < 0.0001) antiproliferative effect at 72 vs. 96h exposure period (concentration range 31.25–250 μM in MDA-MB-231 and 15.62–125 μM in MDA-MB-468 cell line) as indicated by the significant reduction in the IC 50 values, in particular for MDA-MB-468 cells.

The overall reduction was highly significant ( F [2.77] = 48.42, p < .0001) in both groups combined.

Analysis of variance showed highly significant variation due to year-by-genotype interaction effects ( p < 0.0001) in both HRP and CGP ( Table 2 ).

These differences were highly significant ( p < 0.0001).

We also found the level of closest designated trauma hospital was a highly significant predictor of bypass (p<0.0001) with patients less likely to be taken to the closest hospital if it was classified as regional (OR: 0.16) and rural regional (OR 0.09) compared to hospitals classified as major trauma.

The log-rank test confirmed a highly significant difference in the survival distributions between the two groups ( P < 0.0001).

At 12 weeks, the investigators noted a highly significant difference in mean percentage change in tumour size between the study and control groups (–20% vs . +19%, P <0.0001).

The subgroup test was highly significant ( p < 0.0001), reinforcing the etiology-dependent prognostic value of LSM.

This difference in sperm count in both groups was highly significant (t = 11.15; P < 0.0001; df = 9) [ Table 1 , Figure 1 ].

There was a highly significant difference in pN/pS between gene categories (Kruskal–Wallis test: χ 2 = 77.9, df = 6, P < 0.0001; Fig. 2c ).

These results were determined highly significant by a repeated measures two-way ANOVA [F(18,189) ≡ 4.05, p < 0.0001].

The postoperative volumes in the placebo and nucleoplasty groups were 1.078 ml (SD: 0.350 ml) and 0.906 ml (SD: 0.287 ml) respectively; the difference is highly significant (p<0.0001) ( Fig. 4 ).

The test showed a highly significant difference between groups (χ2 = 52.69, df = 3, p < 0.0001), indicating that the species distribution is not uniform across the groups.

The negative correlation between burden and RANTES fold change was highly significant (Fig. 5 c, Pearson r = − 0.27, p < 0.0001).