This effect was further shown to be highly significant for each individual marker by reaching Bonferroni corrected significance ( Fig 3 ; univariate F-tests, p < 0.000).
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As expected, highly significant downregulation of RECK mRNA in cancer tissues was observed ( P = 0.000; Fig. 2A ).
With introduction of another two studies, p value became highly significant (p = 0.00, significant at 99% level of confidence) and stayed significant thereafter ( Figure 4b ).
The between-groups analysis showed a highly significant increase in total sleep duration (p=0.000), duration of deep sleep (p=0.034), light sleep (p=0.000) & rapid eye movement sleep (p=0.000) with a significant reduction in respiration rate (p=0.015) for the Experimental group when compared to Controls.
Although the overall regression is highly significant (p = 0.000, n = 60), the 7 variables just account for 36% (R 2 ) of the total variance.
Logistic regression showed a highly significant result (Wald statistic = 12.3, df = 1, and P < 0.000), with the following classification parameters: sensitivity = 94.7% and specificity = 86.8%; that is, 94.7% and 86.8% of patients and controls, respectively, were classified correctly.
Moreover, mediation analysis in which the direction of causation in the model is reversed, i.e., to explore whether motor deficits mediate between disease duration and cerebral WM FA, we find only weak evidence of this mediation effect (δ = − 0.0003, CI 95% = − 0.0007 to 0, p = 0.06), while the direct path between disease duration and cerebral WM FA remains highly significant (ζ = − 0.0014, CI 95% = − 0.0022 to 0, p ~ 0).
The PHQ9 depression score was higher in sleepy subjects with SES ≥ 11 compared to non-sleepless subjects; the difference being very highly significant (PHQ9=11.97 ± 4.99 and 6.54 ± 5.27 respectively; p=0.0000).
There was a highly significant improvement in GERD symptoms (heartburn, reflux, nausea, vomiting, and dyspepsia) within 2 weeks of dietary intervention ( P < 0.000).
When stratified by disease stage, individuals diagnosed at Stage I–III ( n = 142) exhibited significantly more favorable survival trends than those with Stage IV tumors ( n = 36), with highly significant survival differences ( p < 0.0000; Figure S3 ).
ANOVA revealed highly significant CN variation among the taxa ( F = 44.649, d.f. = 5, p = 0.0000).
5.5%, 4%), which was highly significant (p=.000) (Table 2 ).
Note that the PERG samples clustered far from the origin of the axes, whereas noise samples clustered around the origin, the statistical difference between the two clusters being highly significant (T 2 , P < 0.0000). 26 Figure 4 shows mean amplitude and phase adaptation slopes for different groups.
ANOVA assessment showed that the constructed D-optimal quadratic model is highly significant with a p -value ≤ 0.000.
Analysis of variance (ANOVA) revealed that pH had a highly significant effect on turbidity removal efficiency (F(5,12) = 3446.5, p ≈ 0.000, with a very large effect size (η2 =0.999).
The AMOVA, partitioned 71.35% of variation among the populations and 28.65 within the populations ( S3 Table ), with a highly significant F ST (P = 0.0000; S3 Table ).
In our case, it is highly significant ( P = 0), indicating that there is more than one species in our sample.
The ANOVA showed a highly significant effect of ‘number of subjects' on classification performance (Voting: F(19, 9980) = 3061.83, p = 0.00; ERP averaging: F(19, 9980) = 1634.06, p = 0.00; Feature concatenating: F(19, 9980) = 809.35, p = 0.00).
The ANOVA test indicated a highly significant difference ( P = 0.000), and post hoc comparisons showed that both RArc and h-RArc had significantly higher D 95% values compared to 3DCRT ( P = 0.001 for both).
There was a highly significant correlation between the extracted volume of urine and the amount of ng/tube (r = 0.979, n = 17, p <0.000).
On applying chi-square test between blood group and Decayed, Missing and Filled Teeth (DMFT) score, a highly significant association (p=0.00) was observed.
1B ) were highly significant, but their coefficients of determination were lower than those observed for the corresponding soil-to-hepatopancreas regressions (E1 phase: p = 0.000, R 2 = 0.737; E2 phase: p = 0.000, R 2 = 0.581).
The analysis suggested that the overall model was statistically highly significant ( P = 0.00).
This difference was found to be highly significant (P = 0.000).
A significant positive association (p=0.007) was observed between birthweight and BMI; additionally, adjusting for age and gender, the association with BMI was highly significant (p=0.000).