“highly significant”

These were highly significant differences comparing the four versus two times daily ( P <0.0001, P <0.0001 and P <0.0013) and four versus one time daily ( P <0.0001 in each cohort) schedules.

The analysis revealed a highly significant difference among groups ( F (19, 40) = 2165, p < 0.0001), indicating that emulsification capacity is strongly strain‐dependent.

A highly significant interaction between geometry and CCF inclusion was also identified ( p < 0.0001), demonstrating that the influence of fibre reinforcement on void formation differs according to geometric complexity.

The small subgroup of current smokers ( n = 4) showed a somehow peculiar profile, with highly significant changes in the expression of ICAM1 and NFKB1 ( p < 0.0001 and p = 0.002 respectively) and some other minor variations.

Friedman’s test proved that the effect of the stimulus on perceived fear was highly significant (chi-square = 6130.252, df = 41, P < 0.0001).

Highly significant reactivity was found to peptide 17 (P < 0.0001), which yielded a sensitivity of 93%.

The ANOVAs for both size and shape reveal that the main effect of ‘tooth germ’ is highly significant ( P < 0.0001) compared to digitizing error, meaning that digitizing error in placing landmarks on tooth germs is highly negligible ( S1 Table ).

3B1 and 3B2 indicated highly significant effects of gabazine ( p < 0.0001) and behavior ( p = 0.0002), and further indicated a significant interaction ( p = 0.0314).

In fact, the percentage of astroglial area surrounding plaques increased with plaque size, showing a highly significant linear correlation (Spearman's correlation coefficient r = 0.745, P = .0001). 3.2.

This response to therapy was found to be statistically highly significant ( P < 0.0001).

Day of sampling and the age of the youngest animal in the group were included in all of the models at level 2 and were highly significant in all models ( p < 0.0001).

The log-rank test indicated highly significant differences in lifespan between control and mutant lines (p < 0.0001).

The NIHSS score at admission and the mRS score at discharge were shown to be directly proportional to each other, with a highly significant link (Spearman correlation coefficient = 0.7799; p=0.0001).

The use of tramadol for analgesia was confirmed as a highly significant contributing factor for NAE (OR, 6.3; 95% CI, 3.0 to 13.4; P < 0.0001).

Overlay images of the red and green channels from immunofluorescence co-staining demonstrated distinct patterns of expression, where analysis of MOC K1 and K2 indicated a highly significant negative correlation (Spearman's correlation, −0.8767, p < 0.0001) between GPX4 and Vimentin protein levels ( Fig. 5 K).

To check this we performed real-time RT-PCR on patient lymphoblastoid RNA and observed a highly significant drop of >75% in CARMIL2 expression levels for the F1 proband versus healthy controls ( p < 0.0001).

Regarding HR ( Figure 4A ), a marked and highly significant decrease with age was observed during the first 12 months ( p < 0.0001; r = − 0.833), followed by a relative stabilization during adulthood characterized by a slight increase up to 120 months ( p < 0.0001; r = 0.084), and then another moderate increase between 120 and 220 months ( p < 0.0001; r = 0.300).

The number of SWATH windows was the most critical parameter with a highly significant (p < 0.0001) impact on the number of proteins quantified.

The differences in the mean preoperative 25OHD levels of the patients in each Rep-T transcriptional cluster were highly significant ( P < 0.0001 by ANOVA).

Specifically, the following variables demonstrated highly significant ( p < 0.0001): age, sex, race, depression, household income poverty rate, diabetes mellitus, pulmonary disease, health insurance status, smoking status, marital status, educational level, hypertension, body mass index, and number of COVID-19 vaccinations received.

An analysis of variance on the values of BSS for the locations and factors in the GxExM factorial combination showed that the factor ‘Location’ had a highly significant (p < 0.0001) effect on the BSS (Table 3 , and S1 ).

sPCA analysis revealed highly significant global (p = 0.0001) but non-significant (p = 0.4327) local spatial structures (Supplementary Fig. 2 ), indicating strong signatures of between population separations.

In ULMS, 3 miRNAs—miR-21-5p, miR-27b-3p, and miR-152-3p—had a highly significant underexpression ( p < 0.0001), and 4 miRNAs—miR-129-5p, miR-141-3p, miR-148a-3p, and miR-203a-3p—presented a significant overexpression ( p < 0.0001) (as seen in Figure 3 and Figure 4 ).

A highly significant difference ( P < 0.0001) was found.

Group category had a highly significant influence on WMS total scores ( p < 0.0001), whereas sex narrowly reached significance level ( p = 0.05).