“highly significant”

Behavioral improvements with ramelteon were highly significant ( p < 0.0001), suggesting its potential for treating PTSD and anxiety disorders.

In this example, the reductions in response size relative to rest were statistically highly significant in all three phases of rearing (one-way ANOVA, p < 0.0001, F (3,135) = 21.77; Dunnett's multiple comparison test comparing each phase; p < 0.01 for all comparisons).

Figure 4e shows the highly significant levels of necrosis in neurons caused by MS A-FT ( p < 0.0001).

Regional variance analysis based on clusters corresponding to the GoC and ETP yielded highly significant values (p = 0.0001, Table 2 ) Φ RT = 0.373, Φ PR = 0.040 and Φ PT = 0.398, further validating a tropical-subtropical subdivision.

Strikingly, the activity in lymphoblasts showed a highly significant positive correlation with levels of DHRSX protein in this cell line (see Figure 1 J) (NADH: R 2 = 0.9667; p < 0.0001, NADPH: R 2 = 0.9910; p < 0.0001; Figure 3 E).

The preference for reachable locations was highly significant (χ 2 test, two nearest LEDs against the three farthest ones, P < 0.0001).

Both PD-1 and PD-L1 exhibited highly significant differences in expression levels between the two clusters ( P < 0.0001), with a higher expression in cluster 1.

The overall concordance between the two methods in detecting JCV was statistically highly significant (p=0.0001) with a kappa value of 0.659.

The multiple regression model for color was highly significant (R 2 = 0.84, F 3,110 = 188, P <0.0001), but the slope and intercepts were affected by ecosystem type, which resulted in the following equations: (2) and (3) Despite the differences in the regression parameters, most of the color observations from the experimental ponds fell within the 95% prediction intervals associated with the regression model for natural lakes in equation 3 ( Fig. 2a ).

UUCRs and PUCs showed a highly significant positive correlation when all samples were compared ( p < 0.0001), with ρ = 0.72 (Fig. 4 ).

In males, the difference was highly significant (547.67 ± 19.77 vs. 449.35 ± 13.34, p < 0.0001), and a comparable trend was observed in females (352 ± 16.73 vs. 316.31 ± 11.22, p < 0.0001).

Statistical significance was defined as p < 0.05, and highly significant was defined as p < 0.0001.

Additionally, post hoc Tukey’s test showed a highly significant effect of all 2-DPMP concentrations in both CPu ( ++++ P < 0.0001) and NAc shell ( **** P < 0.0001) against control values where no drug was present.

For MALAT1, the mean expression for SAH patients without CVS was 1.25 with 0.40 SD, whereas that for SAH patients with CVS was 2.76 with 0.77 SD, and the statistical difference between the groups was highly significant (p < 0.0001) ( Figure 1 ).

By performing immunofluorescence (IF) staining of ZRANB1 (green) and MDA (magenta) in the KIRC tissue microarrays, we found a highly significant positive correlation (R2 = 0.47, P < 0.0001) between ZRANB1 and MDA ( Fig. 1, F and G ).

Subsequent analysis of the saliva showed a highly significant linear correlation ( p < 10 −4 ) between the total eukaryotic cell content and the integral of the region, 1.24 to 1.30 ppm, as a surrogate measure of U ( Figure 6A ).

On the other hand, the main effect of bias direction was highly significant [ F (1, 9) = 55.131, p < 0.0001].

A two‐way ANOVA showed highly significant effects of treatment [F(1,59) = 126.4, p < 0.0001], gene [F(5,59) = 75.40, p < 0.0001], and their interaction [F(5,59) = 74.37, p < 0.0001].

Both discriminant functions resulted to be highly significant (P < 0.0001) and the percentage of variation accounted for by the first discriminant function was 63.6% of the variance in the grouping variable.

Lens transmission and pupil responses to blue (470 nm) light Lens transmission of blue light in relation to age Our results revealed a highly significant linear decrease in blue (a peak at 480 nm) light transmission through the lens with increasing age (r = −0.91, p < 0.0001, transmission = 1.08–(0.01 * age), see Figure 4 ).

Non-spatial linear regression of altitude on logarithm transformed concentrations of cyanogens showed highly significant association, (p < 0.0001).

These reductions were highly significant (ANOVA, F = 55.9, P < 0.0001) and 90% of mosquitoes died within 20 minutes of exposure (Figure 2 ).

Both results are highly significant ( p < 0.0001, φ = 0.17 regarding overall publications and 0.18 in the case of lead authorships).

The CC group showed no significant increase in cortisol during stress or drug cue exposure, while the CG group showed a highly significant increase in their cortisol response during stress ( t =4.25, df=109, P <0.0001, Cohen's d =1.46) and drug cue ( t =3.04, df=109, P =0.003, Cohen's d =1.04) relative to the neutral condition ( Figure 2 ).

Additionally, non-parametric one-way ANOVA analysis for comparing methylation levels of one loci in different tissues was highly significant for all loci (CpG-1 and CpG-2 for both male and female subpopulations, Krustal-Wallis test, p<0.0001) A relatively greater level of methylation was observed in most tissues at IAP-LTR, Line-1 and Myc .