“highly significant”

Indeed, comparison of the 500 strongest peaks and 500 hottest hotspots revealed a highly significant correlation ( Figure 3C , p<10 −37 ).

The difference was highly significant (Mann–Whitney p = 1.0E–37); (2) location of matching regions: In non-seed-binding miRNAs/isomiRs, we observed that over half of the matching regions began between positions 6 and 8.

Another study [ 8 ] reported that infection rates are higher in metropolitan cities with large population density in India as they found a fair and highly significant correlation ( r = 0.49, p-value ~ 10 −37 ) at the 5% level of significance.

Examination of the proteins with reduced abundance in the sod-1 mutant showed a highly significant enrichment of ribosomal proteins ( p < 10 –37 ) including 24 RPL proteins, which are in the large 60S ribosomal subunit ( Figure 6 C, Table S6 ).

When we compared these normal HSC commitment-associated DMRs with the DMRs identified in Satb1-deficient HSCs, we found a highly significant overlap (p=1.2×10 −37 ; hypergeometrical testing), with 37% shared hypermethylated DMRs and 15% shared hypomethylated DMRs (overall 22% shared DMRs) ( Supplementary Fig. 6e ).

Fraction Csp3 showed highly significant correlations with Molar Refractivity (p = 1.7613E-37), MolVol (A3) (p = 4.2254E-26), and Druglikeness score (p = 9.35371E-33), while exhibiting marginally significant associations with TPSA(Å 2 ) (p = 0.059100432) and MolPSA (A2) (p = 0.055785406).

For the total number of virulence genes per genome, the difference between ST2250 ( n = 205) and non-ST2250 ( n = 107) genomes remained highly significant ( p = 1.87e − 37, Mann–Whitney test).

NORM ( P = 2.03E-05 in SM and P = 4.84E-06 in SM1), compared with highly significant results in the basic model of the nontargeted analyses ( P = 2.01E-37).

Afterwards, association signals from joint analyses of the 2 datasets ( Table 2 ) consistently showed highly significant association for HLA-DQB1 (P = 2.33×10 −37 ), PSORS1C1 (P = 5.70×10 −10 ) and TNIP1 (P = 4.68×10 −9 ), and also showed some evidence of association for RHOB (P = 3.17×10 −6 ).

Of course, with such huge sample sizes, the difference turned out to be highly significant statistically (Kolmogorov–Smirnov test, P = 4 × 10 −37 ).

The biomarker-derived risk score demonstrated independent prognostic value in CGGA-693 (multivariate Cox hazard ratio = 9.195; p < 0.001) after adjustment for WHO histological grade, with Kaplan–Meier analysis confirming highly significant survival separation (log-rank p = 4.60 × 10 −37 ).

The average sum is much smaller for Model 1 than for Model 4 and the differences between natural and simple design are highly significant (p<10 −36 , Welch's t -test).

Our results ( Figure 5b ) show a highly significant correlation (Fisher's exact test: p -value < 1*10 −36 ) between a nearby marking event and the decision to remove the adjacent bead. 3.5 The effect of pheromone marks and recruitment on context sensitivity Since pheromone markings act as triggers for the clearing behavior, we tested whether the marking rates could explain the context sensitivity described above (Methods and Figures 3d – g ).

We find a highly significant difference between these two means [t-test: t (478) = −13.618, p = 1.51×10 −36 ], indicating that, on average, observers are able to estimate admixture levels from photographs better than chance.

The correlation between mean catch-up saccades per second and microsaccades rate was moderate, with a Pearson correlation coefficient of r = 0.58, a 95% confidence interval of [0.51, 0.64], and a highly significant p-value ( p = 1.99e-36).

Although this genetic risk score shows a highly significant association in Caucasian ( P =3.94 × 10 −36 ), there is no evidence of association in the Chinese population ( P =0.21; Fig. 5 ).

Coexpression of CD47 and IFT57 mRNAs Is Intrinsic to Cancer Cells A highly significant positive correlation was also observed between CD47 and IFT57 mRNA expression across the 1156 cell lines in the Cancer Cell Line Encyclopedia (CCLE) [ 26 ] ( p = 4.6 × 10 −36 , Table 1 , Figure 1 d).

The read accuracy improvement of using ORP over single reads, revealed as a gap between their respective error profiles, was most prominent at Q10 and diminished with higher Q-score filtering; the advantage at Q30 was small yet still highly significant (two-sample Kolmogorov-Smirnov test p = 5×10 -36 and 2×10 -11 for rabies and BCV control, respectively), as any reduction in error rate can be used to detect viral variants with greater sensitivity.

The correlation of IVW analysis is highly significant (β = −0.16, P = 5.91 × 10 −36 ).

These contrasting strategies are highly significant ( P < <0.001, Welch’s t- test, t = 54.6, P = 6 × 10 −36 ; n = 18 for D-lactate, n = 20 for L-lactate) and likely alter competitive dynamics in lactate-limited systems.

Our analysis revealed a highly significant correlation between the 12-protein panel and the classical AD biomarkers (297_CSF: positive correlation: Aβ 42 , R = 0.31, P = 7.5e-0.8; Aβ 42/tau , R = 0.64, P = 6.6e-36; negative correlation: p-tau, R =-0.62, P = 7.5e-33; t-tau, R =-0.76, P = 2.4e-57; Fig. 3 A).

We observed a marked elevation of EP300 protein abundance in HCC tissues compared to adjacent normal liver tissues, with a highly significant difference ( p ≈ 7.60 × 10^−36, Fig. 1 D).

This enrichment is highly significant with a P < 7.98E-36 using the hypergeometric test.

The overlap of the downregulated genes in strains overexpressing the D303A or D346A variants compared to those in the strain overexpressing wild-type RNase E was statistically highly significant ( P < 10 –35 and < 10 –46 , respectively, hypergeometric test).

rs13038305 in relation to plasma cystatin C and creatinine based measures of GFR In the MDC-CC, each copy of the major allele of rs13038305 was associated with a highly significant (P<1 x 10 −35 ) approximately one third of a SD increase of plasma concentration of cystatin C both in model 1 and model 2.