“highly significant”

Highly significant differences were found between substrates in February (F = 5.217; df = 5, 114; p < 0.0001), April (F = 5.983; df = 5, 114; p < 0.0001), and August (F = 7.672; df = 5, 114; p < 0.0001); significant differences in June (F = 4.066; df = 5, 114; p < 0.01), December (F = 4.194; df = 5, 114; p < 0.01), and October (F = 2.948; df = 5, 114; p < 0.05).

As shown in Fig 4 , the IC 50s for serum inhibition of RBD-ACE2r binding showed highly significant (p < 0.0001) correlation (r s = 0.83) with corresponding IC 50 values from titrated PRNT studies.

146.22 ± 41.84 mL/min/100 g, p < 0.008), showing a highly significant correlation with GFR in all subjects (r = 0.75, p < 0.0001).

A highly significant reduction ( p < 0.0001) was also found in the invasion of the co-culture by the HMLN-1 strain when it was co-inoculated (65.6%) and pre-inoculated (97%) with L. reuteri M4-100 ( Figure 3 ).

Moreover, given that the microsatellite loci Tgu 9 and Indigo 41 are in highly significant LD ( P <0.0001) in all of the stocks despite being approximately 5 Mb apart, an immediately adjacent causative mutation would be expected to be in strong LD with the SNPs that we assayed within the MC1R .

After induction of general anesthesia and creation of pneumoperitoneum, a progressive increase in modified LUS score was seen after intubation, after deflation of pneumoperitoneum, 30 min after extubation and 24 h post-extubation compared to the baseline Preoperatively; the difference is statistically highly significant, P < 0.0001 ( Fig. 3 ).

The difference between patients and controls was highly significant (GLM with negative binomial errors, main effect of subject status, LR 1,189 = 108.75, P < 0.0001), accounting for 5.22% of the variance in the data.

The ANOVA results showed a highly significant difference between the groups (F = 2820, P < 0.0001) and an R2 value of 0.9991, indicating that 99.91% of the between-group differences could be explained by changes in the relative expression of NME4.

There was a highly significant inverse effect of SSCseverity on critical COVID-19 illness ( t = −5.66, p < 0.0001).

A highly significant inter‐patient variation in annual progression rate was detected (variance of β r 0.893; p < 0.0001).

The Kruskal–Wallis test for the lateral region was highly significant ( p < 0.0001).

59 Bostanci et al found a significant improvement in both the psychosocial and physical measures postoperatively and highly significant effect on the overall QoL (all p<0.0001). 54 A smaller cohort study looking more specifically at body image perception found a significant improvement postoperatively. 55 Kim et al also observed a positive impact on patients’ QoL and found this to be evident early post-operatively and persistent lo

Statistical analysis confirmed highly significant effects of HC-030031 antagonism (all p < 0.0001), validating the mechanistic importance of TRPA1 in bacterial sensing.

Survival analysis confirmed a highly significant difference between the two cohorts, with OM patients experiencing a substantially reduced risk of death (HR = 0.1974; 95% CI: 0.1095–0.3559; P < 0.0001 by log-rank test).

Linear regression of seasonal curve shape against methodological score was highly significant ( r 2 = 0.3, F = 16.9, P < 0.0001, test for normality = 0.2, P < 0.0001) confirming that the tendency to demonstrate seasonal dynamics between the different retained studies depends largely on the degree of statistical or mathematical technical Sophistication of the study.

All histologic parameters showed highly significant changes (each p<0.0001) 31 days postoperatively, except the irritation of the lamina elastica interna (p = 0.22).

Detection of recombination, using the pairwise homoplasy index test (PHI-test), was marginally significant in the HCV Sanger data set ( P = 0.043), and highly significant in the HIV-1 data set ( P < 0.0001).

The results in Figure 8 show a highly significant correlation between the potency of both compounds in the cancer cell lines, with an R -value of 0.852 ( p < 0.0001 ).

For all 16 intersections of pairs of gene lists, the enrichment was highly significant ( p < 0.0001) ( Table S2 ).

One-way ANOVA indicated that the model was highly significant (p<0.0001) with high F values (15.64).

For the northern strain, the analyses showed a highly significant dependency of diapause on day length, when different constants were estimated for each T-cycle treatment (Fig. 2 a, b; n = 24, df = 18, dev. = 103.79, p < 0.0001).

Statistical significance was set at p < 0.05, with p < 0.001 indicating a highly significant result and p < 0.0001with highest significant.

The calcium model was highly significant ( p -value = 0.0001) and showed no lack of fit ( p -value = 0.9114).

The interaction between plasma treatment and salinity was highly significant ( P < 0.0001) across all GP parameters, highlighting the complex relationship between these two factors.

Publication bias As demonstrated by funnel plot asymmetry, a highly significant publication bias was observed in our study using Egger’s test ( t = 4.12, P = 0.0001) and Begg’s test ( P = 0.001) (Fig. 5 A, B).