“highly significant”

Among these, four genes showed high statistical significance ( G2E3, p = 0.0031, FC = 1.9; ZNF695 , p = 0.0096, FC = 2.0; CEP41 , p = 0.0023, FC = 2.2; RGPD1 , p = 0.0031, FC = 2.9), whereas the remaining six genes were highly significant ( NOL4, p = 0.0003, FC = 3.1; SOX6, p = 0.0003, FC = 3.2; GOLGA6C, p = 0.0002, FC = 5.9; PCDHA9, p = 0.0001, FC = 11; GOLGA6B , p = 0.0009, FC = 4.1; LMLN , p < 0.0001, FC = 3.4).

A Fisher test was performed to demonstrate that Tbx21 module was significantly enriched with peaks: highly significant peaks (macs2 peak score >50) mapping to blue module (63/588) were significantly more enriched ( p = 0.0003) than turquoise module peaks (44/805).

The increased incidence and number of metastases using the K1735p tumor was highly significant in C3H/ gld mice compared to C3H controls (difference in incidence between C3H and C3H/ gld P = 0.0003 using a one-sided χ 2 test; difference in number of lung metastases P < 0.0001 using a Mann-Whitney test).

Tapping variability, SD asy A highly significant effect of condition on SD asy was found using a likelihood ratio test (χ 2 (2) = 16.5, p = 0.0003).

The intereye concordance of MA in the study eye and in the fellow eye at year two was highly significant ( P = 0.0003).

All comparisons between DEA and REF were highly significant (pairwise ANOSIM R ≥ 0.705, p = 0.0003).

burtoni genome had DMRs, which was highly significant (both OR > 5.8, p < 3e-4).

Results Premating isolation For five of six species/type combinations we identified a highly significant female × male interaction effect due to the reduced mating of heterotypic pairs (each LRT χ 1 2 > 10 and each P < 0.0003; Supplementary Figure S2 ), indicating the presence of strong premating reproductive isolation.

On genotypic analysis this association was also highly significant (χ 2 = 16.39, P = 0.0003) ( Table 4 ).

The interaction between B-Current and C-pH (BC) was highly significant (F = 38.13, P = 0.0003), indicating that the effect of B-Current on COD removal efficiency is dependent on the C-pH level.

For patients with neutropenia who did not have systemic infection (group2), that is, those who were diagnosed with FUO or localized infection presented low concentrations of PCT (0,08–2,15) that were highly significant (p = 0,0003) and CRP concentrations that did not greatly differ statistically from those found in group 1 (19,5–546,0) (p = 0,9198).

vivax attacks shows a highly significant positive correlation with maximum or overall P. falciparum parasitemia (R = 0.12 and 0.05, p = 0.0003 and 0.005 respectively) but negligible or no significance with P. vivax parasite density phenotypes (Maximum: R = 0.1 p = 0.02, not significant after Bonferroni's correction and overall: R = 0.07 p = 0.25), (iii) Maximum P. falciparum density shows a positive correlation with maximum P. vivax density (R = 0.22, p = 0.0002).

EdU staining assays indicated a highly significant decreased cell proliferative potential ( P = 0.0003; Fig. 6F, G ).

Among all disease groups, a highly significant association ( p = 0.0003) of the rs1333049 variant was found with MetS/MetS-CHD − showing C allele carriers at a 4.04 times higher risk of MetS compared with non-carriers (OR = 4.04, 95% CI = 1.62–10.07).

Additionally, the overall opinion of scar quality demonstrated a strong regression model ( R 2 = 0.527) with a coefficient estimate of 1.036 and a highly significant p ‐value ( p < 0.0003).

A one-way ANOVA and subsequent Tukey–Kramer multiple comparisons tests revealed a highly significant effect of storage time on particle size [F(3, 8) = 22.722, p = 0.0003].

The difference of ECVM-treated (n = 9) versus control (n = 11) eyes was still highly significant (p = 0.0003, Mann Whitney test; Figure 2 C).

Group A showed a mean reduction in the ulcer area by 8.26 mm 2 ( 75.99%) which is highly significant ( P -value = 0.0003) [ Table 4 ].

Comparing the number of doublings per passage between the two conditions, we found the difference to be highly significant (paired t test p=0.0003), confirming gain-of-function with the mutant allele.

TC299423 had a highly significant overall effect on the CPP difference score in the mutant α6L9′S mice [One-way ANOVA, F (4,45) = 6.706, p = 0.0003], but not in WT mice [One-way ANOVA, F (4,60) = 1.442, p = 0.2312] ( Figures 4A,B ).

Size metrics show highly significant differences: mean Feret diameter (U = 87, p = 0.0003, r = 0.64), median Feret diameter (U = 90, p = 0.0004, r = 0.62), and SD Feret diameter (U = 120, p = 0.0045, r = 0.50), with Los Villares exhibiting larger and more variable grain sizes.

Specifically, 74% (34/46) of concussive blast TBI patients were found to have 2 or more regions of abnormal FA and this was highly significant by chi-square compared to combat-deployed controls ( p = 0.0003). 3.2 Quantitative volumetric findings Quantitative volumetric analysis revealed that the DTI findings were not likely influenced by significant reductions in the brain anatomy but rather from microstructural injury to the regions themselves.

The difference of 9.8 ng/mL was highly significant ( P < 0.0003; Fig. 1 ).

When analyzing amino acids with reactive side chains, we found in non-transferred peptides a highly significant enrichment of lysine, methionine, and tyrosine and depletion of aspartic acid (P = 0.0003).

After one week of SFOH intake, a highly significant increase in Fe(2+) and Fe(3+) was observed in the patients' stool supernatant (p = 0.0003 and p = 0.0085, respectively), which then decreased by week 4 (t2, V2, endpoint of the study), but was still significantly higher (p = 0.0028 and p = 0.0424) than at baseline t0 (Fig. 6 ).