“highly significant”

At 1 hr, a highly significant (t (8) = 6.033 P = 0.0003) suppression of the IL-10 response was seen in the p38α KO mice.

The difference in aggregation index (AI [%]) values was highly significant ( p = 0.0003) between Control vs.

The relationship between STX1A and PC1 remains highly significant (one-tailed Pearson correlation, n = 62, p = 0.0003).

other) was highly significant [ F (1, 16) = 20.49, p = 0.0003], while the effect of experiment (1 vs. 2) was not significant [ F (1, 16) = 0.38, p = 0.55], and there was no interaction between these factors [ F (1, 16) = 0.06, p = 0.81].

In order to define an appropriate drug concentration, tetracycline response experiments were conducted, whereupon embryos infected with 1500 CFU SH1000 EryR (GMSA015) were immersed in sterile E3 medium containing a range of antibiotic doses for the duration of the experiment ( Figure S3A ).While 50 μg/ml tetracycline produced a highly significant, curative response ( p = 0.0003), 10 μg/ml tetracycline showed a trend towards curing ( p = 0.0753) and 5 μg/ml was entirely sub-curative ( p = 0.2181).

The median intra-individual reduction in BMI-SDS was −0.20 SDS (IQR −0.28 to −0.10, full range −1.0 to 0.1), which was highly significant (Wilcoxon signed-rank test p = 0.0003) with a large effect size (r b = −0.77).

Compared to homozygous common allele carriers, heterozygous for the T variant were found to be at a highly significant 5.59 -fold increased risk of developing endometrial cancer (95 % CI = 1.96–15.91; p = 0.0003).

Interestingly, we found a highly significant interaction effect between Distribution Type and Standard Vowel [ F (1,18) = 20.22, p = 0.0003, η p 2 = 0.53], which shows that the attested difference between unimodally and bimodally trained Dutch 2-to-3-month olds differs depending on the standard that they hear in the oddball test (see section Exploratory Results for the Four Groups).

In group G4, the improvement was more pronounced and also highly significant ( p = 0.0003).

T-test comparison of SA versus UD means for discriminant function score, paired by clinician, replicated the overall results with a highly significant mean difference 1.77 points (p = 0.0003).

The ANOVA described above revealed a highly significant main effect for the type of DRNN/EMG pairing [ F (2, 14) = 23.61; p = 0.0003].

In vascular surgery, the difference in the glitch rate between site E (mean of 6.3 glitches/hour) and site D (mean of 10.5 glitches/hour) was highly significant, p=0.0003.

Overall the tetanic stimulation resulted in a highly significant alteration in the EPSP-IPSP patterns (p=0.0003; Rank-Sum-Test).

As shown in Table 2 , the presence of synchronous metastases did not have a significant effect on the survival of patients with the smaller tumors <5.5 cm (P = 0.63), but it had a highly significant effect on the survival of patients with larger tumors ≥5.5 cm (P = 0.0003).

Indeed, we found a highly significant negative correlation between ADAMTS15 and CITED2 expression levels at H6 in both patient and control groups (combined data: rho = −0.75; P = 0.0003; Figure 4 ).

However, pmax decreased across gestation in overweight/obese women, whereas it increased for normal weight women ( Figure 2a ); this difference in rate of change between groups was highly significant ( P =0.0003).

The correlation between acidification and solubilization was moderately positive and highly significant (R = 0.391; p = 0.0003), confirming that pH reduction favors K release from phonolites ( Figure 2 ).

When analyzing amino acids with reactive side chains, we found in non-transferred peptides a highly significant enrichment of lysine, methionine, and tyrosine and depletion of aspartic acid (P = 0.0003).

Application of nicotinic PAM after xanomeline yielded a highly significant increase in peak amplitude (paired t -test, t 11 = 5.3, P = 0.0003; Fig. 5B ), charge transfer (paired t -test, t 11 = 4.7, P = 0.0007; Fig. 5C ) and rise speed (paired t -test, t 11 = 5.7, P = 0.0001; Fig. 5D ).

PACo analysis revealed a highly significant global fit between host and symbiont phylogenies ( p = 0.0003).

Overall, we obtained a strong and highly significant (r = 0. 76, p = 0.0003) covariation between the number of mutations at non-CpG per unit sequence and the number of mutations at CpG per available CpG ( S1 Fig ), showing that the scaling-up of the substitution rate at CpG's is of similar magnitude across bins.

The effect of claw on the variance of the difference between the two measures was highly significant (−2LL difference 48.2; df.18; p < 0.0003).

Being the difference between the two adjusted means (−65.08) highly significant ( p = 0.0003), the most important factor affecting the ASV reduction observed in women with HR-HPV clearance was due to the treatment with the probiotic (Online Resource 16).

All immunized mice except a single animal from each vaccine treatment were protected and survived challenge (94% survival) which was highly significant in comparison to naїve mice (25% survival, p = 0.0003; Figure 2E ).

Surgical resection was a highly significant factor reducing the risk of death by 74% ( P = 0.0003; hazard ratio 0.26, 95% C.I. 0.12 to 0.55).