“highly significant”

However, when we performed mediation analysis, conditioning on the expression of TOP2B , the association between CX-5461 IC 50 and MYCN expression was lost ( P = 0.8), but TOP2B remained highly significant ( P = 2.7 × 10 −4 ), suggesting that the association between MYCN and CX-5461 IC 50 was mediated through MYCN ’s effect on TOP2B expression.

The difference among body mass distributions of extinct, introduced, and remaining frugivore species was highly significant (ANOVA, F 37,2 = 10.343, p = 0.00027; Kruskal–Wallis Χ 2 = 16.477, p = 0.00026, see Supplementary Fig. 1 ).

A highly significant association with Gleason score was observed when the data was combined from these three studies with an Odds Ratio (OR) of 0.85 (95% CI = 0.77–0.93; p = 2.7×10 −4 ).

Finally, there was a highly significant positive correlation ( F = 14.10; df = 1; P = 0.00027) between protein quantity and diCT sensitivity.

Association mapping revealed highly significant marker trait associations at Bonferroni correction P < 0.00027.

While this is highly significant ( p = 2.7 × 10 − 4 ), this deviation is not unexpected given the very significant differences in MAF between groups.

The facial lesions were found frequent in young patients below 19 years (38/61; 62.2%), while the limbs lesions were described more in older ages (≈ 86%), with highly significant differences observed among the patients age groups ( P =0 .000273, chi-square).

The highly significant differences occurred between SF of 2 Gy and SF of 2 Gy + RGD-PEG 2000 -AuNPs 30nm ( p = 0.000275) and 2 Gy + RGD-PEG 2000 -AuNPs 10nm ( p = 0.00016).

The difference in DogCV prevalence was highly significant ( P = 0.0002755) in diarrheal dogs.

If we consider the trends being predicted by nucleotide content as being a “success”, then this pattern (16 successes, 1 fail) is highly significant (binomial test P -value = 0.00028).

The most significant pathway (P = 0.00001) related to the biology of the innate and adaptive cellular immune response ( Table 2 ), followed by the adaptive response (P = 0.00023) and a number of highly significant and closely related pathways relating to polymorphism in the Fibroblast Growth Factor receptors (FGFR) and their ligands (minimum P = 0.00028).

The ANOVA Welch test demonstrated that there were highly significant differences between these total BA values ( Table 3 ), as expected ( p = 2.84 × 10 −4 ); such differences were largely explicable by those observed between the cheese and wine/vinegar product classifications investigated.

Eight of 135 H/L and two of 422 TCGA White tumors had overexpression of KIAA0100 ; the frequency difference is highly significant ( P = 0.00029, Fisher exact test).

3M ) revealed a highly significant reduction (48±19%) in the number of GluA4 clusters in the OPL of GluA4fl/fl:Cx57+/Cre mice (p = 2.9×10 −4 ).

In contrast, the percentage of pulp presented highly significant differences (F3,8 = 22.64, p = 2.9 × 10 −4 ).

Statistical analysis reveals a highly significant difference between the two models ( p = 0.00029, ∗∗∗ denotes p < 0.001).

The Kruskal–Wallis test indicated a highly significant difference in MPO expression among the groups (H = 16.29, p = 0.00029), with mean rank scores of 5.5 for Group A, 17.71 for Group B, and 9.79 for Group K.

However, very large and highly significant differences emerged in career concerns, with trainees and nontenured faculty reporting higher levels of concern compared with those with permanent positions ( p = 2.90E‐04, d = 1.37).

Overall, the interaction between origin and resource chosen was highly significant (factorial ANOVA, F 1, 32 = 16.6, P = 0.00029: Figure 1 ).

A paired Wilcoxon signed-rank test confirmed a highly significant reduction ( W = 0, p = 2.93 × 10 −4 : n = 18, N = 14), with a very large effect size ( r = 0.88).

Patients infected with variant B.1.1.519 showed a highly significant adjusted odds ratio (aOR) increase of 1.85 over non-B.1.1.519 patients for developing a severe/critical outcome ( p = 0.000296, 1.33–2.6 95% CI) and a 2.35-fold increase for hospitalization ( p = 0.005, 1.32–4.34 95% CI).

The results revealed an overall highly significant increase in the expression levels of miR-155-5p in patients compared to controls ( p = 0.0003) ( Figure 3 A).

MCT1 and MCT4 in relation to PFS and OS Membrane-associated MCT1 exhibited a highly significant impact on PFS (p = 0.0003, log-rank test) and, even more pronounced, on OS (p = 1 × 10 –5 ), see Fig. 2 .

The highly migratory cell lines (BxPC-3 and Panc-1) presented the highest oxygen consumption rate (OCR) ( Figure 1 E), and a highly significant correlation was observed between myoferlin abundance and basal OCR (r = 0.9997, P = 0.0003). 2.2.

The Pearson correlation test showed a highly significant correlation (r = 0.83; P = 0.0003).