“highly significant”

The criterion of evaluating statistical significance was as follows: P value < 0.033 was considered significant and marked as *, P < 0.002 as highly significant and marked as **, P < 0.001 was very highly significant and marked as ***.

Comparison of the transcript abundance between promoter-methylated and promoter-unmethylated genes revealed a highly significant negative correlation ( p < 0.001) between gene expression levels and promoter methylation levels, especially in the CG and CHG contexts ( Fig 4B ).

In our study, the differences in number of patients who could complete the 6MWT was statistically highly significant for both procedures ( P <.001).

Highly significant improvements in VAS scores at rest and with activity ( p <0.001) were evident.

This difference was highly significant ( t = −4.055, p < 0.001) and indicates that the effectiveness text module served the intended function. 3.3.

A P < 0.05 was considered statistically significant, P < 0.01 highly significant, and P < 0.001 very highly significant, while P > 0.05 was considered to be statistically insignificant.

The Mantel test showed a highly significant correlation between genetic divergence, denoted by pairwise F ST /(1 − F ST ), and geographical distance between the Japanese populations (Mantel's r = 0.511, p = 0.001).

The log-rank Chi-square was 74.051, with a highly significant P value <0.001.

More specifically, in putative antigen binding sites (ABS), d N /d S values were highly significant ( p < 10 -3 ) and ranged from 4.081 for D. rotundus to 4.939 for C. perspicillata .

In cases of HPV 58 single infection, a more highly significant progression rate, compared to other high-risk types, was observed at 6 months (relative risk [RR], 3.3; 95% confidence interval [CI], 2.04 to 5.30; p < 0.001) and 12 months (RR, 5.03; 95% CI, 2.56 to 9.91; p < 0.001).

There was a highly significant difference in swelling between groups 1 and 2( P < 0.001), and the swelling was more pronounced in group 2 subjects [ Table 3 ].

The difference in cumulative yield between the normocalcemic and severe SCH groups was statistically significant ( p = 0.030), indicating that SCH negatively affects cumulative milk production, particularly in more severe cases. Multiparous cows produced significantly more milk (3,454.42 ± 114.84 kg) than second-parity (3,296.42 ± 128.19 kg) and first-parity cows (2,637.15 ± 121.14 kg), with a highly significant difference ( p < 0.001).

When these comparisons were grouped according to whether the protocol specified no chemotherapy, sequential chemotherapy, or concurrent chemotherapy the heterogeneity between these groups was highly significant ( P =.001).

Results In multivariate linear regression models, there was a highly significant negative correlation between PM 2.5 concentrations and both FT4 (p<0.001), and FT3 levels ( p <0.001).

Sample Type and Tumor Site Distribution Across FGFR4 Mutation Groups The distribution of sample types across FGFR4 mutation groups revealed highly significant differences ( p < 0.001, q < 0.001) shown in Figure 4 D.

The platelet count also showed a highly significant difference ( p = 0.001), with group D having the lowest platelet count (288.83 × 103/mm3), significantly lower than groups A ( p = 0.002), B ( p = 0.009), and C ( p = 0.002).

3 Results 3.1 Sports performance 3.1.1 Peak power (PP) The results ( Figure 3 ) showed a highly significant main effect of PP across each sprinting time point in males, F (5, 24) = 44.96, P < 0.001, η 2 partial = 0.90.

Results There was a highly significant effect of treatment water on the percentage time that larval clownfish spent in the water stream containing predator odour ( F 1,57 = 125.91, p < 0.001), but no effect of test water ( F 1,57 = 0.20, p = 0.66) and no interaction ( F 1,57 = 0.06, p = 0.81).

All DD coefficients were highly significant from the reference level (P < 0.001).

A highly significant association was found between professional categories and avoidance of smoking in hypertensive patients (AOR, 7.98; p = 0.001) and diabetics (AOR, 14.78; p<0.001) (Tables 1 and 2 ).

Highly significant ( P < 0.001) positive correlations were seen between different developmental stages in the same location (Figure 1 ).

Phenotypic diversity and GWA study The analysis of variance revealed a highly significant ( P < 0.001) variability due to the genotypes for all traits (Table 1 ).

A highly significant reduction in dry weight in the complete and partial fasting groups ( P < 0.001 for both) was noted, unlike the non-fasting group, where no significant weight changes were noted ( P = 0.75).

This overlap between cohort 1 and cohort 2 was highly significant ( P <0.001) (permutation test, based on 1000 random shufflings of H3K4me3 peaks genome-wide).

We found 558 contigs with highly significant correlations (p < 0.001); 206 of these were positively correlated, while the remaining 352 were negatively correlated ( Supplementary Table S3 ).