The PHQ9 depression score was higher in sleepy subjects with SES ≥ 11 compared to non-sleepless subjects; the difference being very highly significant (PHQ9=11.97 ± 4.99 and 6.54 ± 5.27 respectively; p=0.0000).
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A highly significant decrease in the value of the Stroop effect indicates improvement ( P = 0.000**) with aripiprazole and visual–spatial constructive ability ( P < 0.001).
The mean value of the responses to the questions related to the overall experience of the pain before visiting the pain clinic was 3.81 ± 1.42 and after visiting the pain clinic was 2.14 ± 1.05 which was highly significant ( P = 0.000).
The mean mandibular condyle inclination (Table 5 ) in horizontal (HCI) and vertical (VCI) planes demonstrated highly significant differences between both groups with P < 0.000, while anteroposterior mandibular condyle inclination (APCI) showed no significance in which horizontal and vertical condyle inclinations relative to horizontal (HP) and vertical planes (VP) were higher in the TMD group (6.32 ± 3.60 and 79.39 ± 6.20°, respectively) than the non-TMD group (4.41 ± 2.48 and 75.08 ± 6.60°, respectively).
Hole cross test (HCT) The F-statistic from the analysis of variance has appeared to be highly significant (F = 12.33; p = 0.000), showing statistically significant variation across the groups in the hole cross test.
Frequency of persistent pale stool between BA and non- BA were 88 vs 8 (83.0 % Vs 21.0 %) which was highly significant (p=0.000).
Furthermore, statistical analysis revealed a highly significant difference in HBZ gene expression among the study population (CI 95%- p = 0.000).
Similarly, total consumption and total number of analgesic doses were lower in group L than in group F and were highly statistically significant [ Table 3 ].There was no significant difference in the Aldrete score between the groups ( P > 0.05) in PACU, but the time taken to achieve an Aldrete score >9 was shorter in group L (7.41±1.80min) than in group F (13.13±2.09min) and was highly significant statistically ( P =0.000).
Knowing someone with OA emerged as a highly significant predictor, making participants over 10 times more likely to have high knowledge (Exp(B) = 10.217, p = 0.000).
The higher transmissibility of the Alpha lineage causes the number of descendants in the Alpha lineage to be highly significantly larger than that in the Alpha-like lineage ( n = 92,688 vs. 259, P value < 4.9 ×10 −324 ).
We note that the P -value of the Spearman correlation was highly significant in every single case ( P -value <2e-308) because of the large number of data-points.
Treatment of WT U-2 OS cells with arsenite showed a highly significant and global shortening of RNA upon stress (Mann–Whitney, p-value<10 –307 ) in stark contrast to ΔΔG3BP1/2 cells that showed substantially less shortening (Mann–Whitney, p-value<10 –5 ) ( Figure 6e , Figure 6—figure supplement 1g and h ).
The chi-square test value was highly significant with a p -value <1.0e−300.
The rejection of unimodality was supported by a highly significant dip test 21 (dip = 0.086275, p < 10 –293 ) using the Python “diptest” package available at https://pypi.org/project/diptest/ .
(2018) , which also tested for ASE in crosses between PAXB and RABS in the VTP, we found a highly significant overlap (Fisher's exact test, P = 8.83 × 10 −292 ).
In agreement with the elevated transcription in the HEID, genome wide, RAD50 showed a strongly positive (cor = 0.565) and highly significant ( P = 2.4 × 10 −281 ) correlation with transcriptional strength.
Both population ( P =1.88e-238) and OA ( P =0.000e+00) had highly significant effects on survivorship, and there was a significant population×OA interaction ( P =9.78e-263; Table 2 , Fig. 3 ), with populations responding differently to OA.
The loci at chromosome 6 at the TREM2 locus, in cis, and chromosome 11 at MS4A locus, showed highly significant association ( P < 1.5×10 -250 ; Table S 4 ) in plasma, indicating shared genetic regulation between CSF and plasma.
The analysis revealed a statistically highly significant distinction ( p = 4.95e-247) between the predicted scores of the causal and non-causal associations (Fig. 3 b).
3 a) SV755331 is localized within LD with rs6889665 exhibiting a highly significant association with recombination hotspot activity (p-value = 2E-246) [ 44 ].
The Mann–Whitney U test showed highly significant differences between male and female body weights in both unadjusted ( p = 2.7 × 10 −223 ) and adjusted ( p = 2.7 × 10 −193 ) groups.
This increase closely resembled the bone resorption marker CTX pattern, with DVP showing a highly significant correlation with CTX ( p = 1.1E −222 ), as illustrated in Figure 5 .
However, here we found that ToxoNet exhibited a highly significant overlap in protein interactions with both T . brucei (283 common interactions, p = 6.4E-204) and Plasmodium (450 common interactions, p = 0; S6B Fig ).
Among the 12 genes related to hormone secretion, Vgf (nerve growth factor inducible) showed a highly significant increase in expression in GCGR-KO α-cells (Log 2 FC = 1.38; p = 2.21E-203) (Fig. 4a ).
In the present study, we found a highly significant enrichment of long TRD sequences in RA compared to healthy individuals ( P = 7.91e − 202, Additional file 32 : Fig S7).