The interaction term potentially allowed the effects of a pharmacologic agent to vary by pulse; because an omnibus likelihood ratio test indicated that interaction term was highly significant ( p < 0.001 for both AUC and Max Change), this term was retained in the final model.
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Correlation equations proved a highly significant correlation of AoR baseline z -scores with losartan dosages, showing that more affected patients received higher up-titrated losartan dosages ( r = 0.407, p < 0.001; Fig. 4 c), thereby keeping AoR progressions constant, independent of baseline AoR z -scores (Fig. 4 d).
The Cox-model found a significant influence of water status (p < 0.01) and a highly significant influence of extreme precipitation events (p < 0.001) as determinants for survival.
The mean (± SEM) cAL increase was 11 ± 2 μm at 3 D, 14 ± 2 μm at 6 D, and 26 ± 2 μm at 9 D, with all pairwise comparisons highly significant (all P < 0.001), except the difference between the 3 and 6 D stimuli ( P = 0.48).
As the effect associated with NHS healthcare experiences in the partial model excluding trust is very highly significant (AOR=1.46, 95% CI 1.27 to 1.67, p<0.001), although lower than the effect associated with trust in the partial model excluding NHS healthcare experiences (AOR=2.06, 95% CI 1.8 to 2.36, p<0.001; AOR=2.06, 95% CI 1.8 to 2.36, p<0.001), it seems plausible that the effect of NHS healthcare experiences on uptake may be mediated by trust: a possibility to which we shall return in the exploratory analysis presented in the following subsection.
The inflammatory state of the pulp tissue as reflected by MMP-9/TP levels and NaOCl lavage had a highly significant ( P < 0.001 and P = 0.004, respectively) impact on pulp survival, while mild preoperative discomfort did not.
Note that also when pooling the data of the 2 grid positions, the EM effect in MG is still highly significant (shift = 0.11, P < 0.001; Bootstrap CIs = [0.096 0.126]).
In contrast, the mortality rates of snails in the WPN group, WPN + SHAM group, and WPN + SHAM# groups showed highly significant differences ( P < 0.001) at time points from 6 to 48 h (Additional file 9 : Table S4).
KaplanMeier survival times curves showed particularly lower survival probability over time for MMPPI score >8 [ Figure 2 ] and a highly significant difference between the four MMPPI categories (Chi-square statistic = 230, P < 0.001).
The K values decreased further in the postoperative period and the change was highly significant ( P < 0.001) as compared to preoperative value but not significant ( P = 0.059) when compared to intraoperative values. α-angle (which represents the speed of solid clot formation) measured at preoperative, intraoperative, and postoperative time points had mean values of 54.80 ± 5.40 min, 61.94 ± 7.87 min, and 68.57 ± 5.70 min, respectively [ Table 3 ].
However, when the study group was compared with control group, it was highly significant ( P < 0.001).
ANOSIM indicated that differences in the prey spectra between the three species were highly significant at prey family-level (R = 0.784, P < 0.001) but non-significant at the level of order (R = 0.079, P = 0.063).
There were highly significant differences (p<0.001; ANOVA) in FFEs between the tested masks.
Table 6 reveals a highly significant difference regarding subtalar flexibility in the right foot ( p = 0.001); also, for plantar index arch, the p value was significant value, indicating that at EV2, the values were not significantly different between the two groups.
Changes in miRNA Expression in the Liver 24 h after DMBA Treatment A total of 24 h after DMBA treatment, there was a highly significant ( p < 0.001) increase in the expressions of miR-134, miR-132, miR-124-1, miR-212, and miR-155 in the liver of DMBA-treated female mice compared to the control group ( Figure 1 A).
The difference was found to be highly significant ( p < 0.001) compared to pure DC and DC-LP.
We found that 25 genes in the PDGF pathway were associated with KIRC progression with a statistical difference ( P < 0.05), among which 12 genes had a highly significant difference ( P < 0.001).
The fixation indices showed that genetic differentiation at all the three hierarchical levels was highly significant ( Fsc = 0.13165, Fst = 0.71915 and Fct = 0.67657, p < 0.001). 2.2.
Further, median differences between SZ and HDs were highly significant ( Figure 5 E, p ≤ 0.001), and also AF patients showed higher sCD25 levels than HDs ( Figure 5 E).
GSEA revealed highly significant associations with the Rap1 signaling pathway ( p ≤ 0.001, normalized enrichment score: 1.88), Oocyte meiosis ( p ≤ 0.001, normalized enrichment score: 1.77), the Fc epsilon RI signaling pathway ( p ≤ 0.001, normalized enrichment score: 1.78), the MAPK signaling pathway ( p = 0.003, normalized enric
The difference between the slopes was highly significant (F = 31.50, DFn = 1, DFd = 26, p < 0.001) ( Figure 6 ).
A two-way ANOVA showed a highly significant ( p < 0.001) effect of concentration and exposure time (harvest) on growth parameters, except for root fresh weight (RFW) and leaf fresh weight (LFW) for the effect of exposure ( Table 1 ).
0.027%, for cohorts I and II, whereby the risk difference was highly significant ( p < 0.001; log-rank test).
HR resulted in highly significant differences ( p < 0.001) among all the measurements except between the fifth (post RLE 240°/s) and seventh (post LLE 180°/s) measurements.
In an analysis involving only the workers who reported suffering from headaches, a comparison of the 2 genders showed that headache impact on productivity was significantly higher in females ( n = 368; age 46.8 ± 10.7; HIT-6 = 53.3 ± 8.5) than in males ( n = 141, age = 43.7 ± 11.1; HIT-6= 49.6 ± 8.50), The disparity, evaluated by means of the Mann–Whitney U test, was highly significant ( p < 0.001).