“highly significant”

Using GSEA, we found highly significant (P < 0.001) enrichment of the differentiated effector signature in KLRG-1 Hi compared with KLRG-1 Int effector cells ( Fig. 5 D ), confirming our hypothesis that terminal effector cells are relatively more differentiated effectors than memory precursors.

All comparisons between tadalafil (5 mg or 10 mg) and placebo were highly significant (p < 0.001).

The correlation was highly significant (R 2 = 0.739, p<0.001).

aureus -inoculated diabetic wounds showed a significant delay compared with non-inoculated diabetic wounds (59% versus 84%; p < 0.05) and were highly significant compared with healing in non-diabetic wounds (97%; p < 0.001).

What really stood out was the highly significant (p<0.001) effect on the odds of being stunted in adolescence for children who were moderately and severely stunted in childhood compared to children who had a normal height according to their age and sex, i.e. not stunted under-five children.

The difference between the individual temperature groups at low and high concentrations is therefore small. From an ANOVA analysis, we found that the effect of doxorubicin concentration on NHEK viability was highly significant [ F (6,161) = 165.213, p < 0.001], as was the effect of temperature on NHEK viability [ F (6,161) = 37.054, p < 0.001].

This treatment difference in week 4 of the second generation was already highly significant ( F 1,118 = 42.13, P < 0.001) and it had become absolute by 8 weeks, when nymphs were entirely absent from all the populations exposed to 2.7% rifampcin and 11 of the 16 populations exposed to 0.9% rifampicin.

As seen in Table 1 , the children in the index group (breath holders) showed low threshold of responsiveness while comparing with the control group and the difference is statistically highly significant with the P value <0.001.

Differences for both were highly significant ( P < 0.001, Kruskal Wallis) across clinics [ Figure 1 ], indicating the magnitude of SCL-90+ subscale scores in the four clinics, shows that for all subscales except somatization, patients in Psychiatry had the highest mean values.

One group demonstrated a highly significant (>200-fold; P < 0.001) induction of anti-ClfA IgG2a titers when mice were vaccinated with ClfA and c-di-GMP as compared with vaccination with ClfA alone ( Karaolis et al., 2007a ).

The relationship between staining intensity and mortality was highly significant (P < 0.001 by the chi-square test).

Strong (correlation coefficients 0.74–0.86) and highly significant ( P <0.001; Spearman's correlation test) correlation was observed between the microarray- and qRT–PCR-generated expression data.

A highly significant (P < 0.001) increase in the villus cell PCNA labeling index was found in the duodenum, proximal, and distal jejunum of transgenic compared to control mice while no significant differences in PCNA expression were detected in their il- eums or colons (Fig. 4 D and data not shown).

The multivariate analysis for associating expression values of the entire miR cluster with miR17-92 locus gain revealed a highly significant association ( P <0.001).

These differences between GPs and specialists were highly significant ( p < 0.001, MWU).

There are highly significant differences between the samples concerning anxiety (P<0.001), the mean value of the patients being markedly higher than that of the general population.

The difference in ORs between ER-positive and ER-negative tumors is consistent across studies ( Figure 1 panel A), and it is highly significant even after permutation adjustment for multiple comparisons (P<0.001).

A highly significant benefit from combination chemotherapy was observed in patients with a good performance status (HR = 0.76, p < 0.001).

There was a strong and highly significant association between baseline Ntx and the occurrence of a skeletal complication ( P <0.001; test of association).

Differences between the responding patients in the four language groups regarding their understanding of the stage of their disease and that indicated by their hospital record are shown in Table 2 ; these differences are highly significant ( P =0.001).

Biological results Apoptosis and proliferation Prior to treatment there was a highly significant positive correlation between proliferation, as measured by Ki67 and AI samples (rho=0.60, P <0.001), Figure 1 .

SaTScan detected five geographic clusters of malaria, one of which was highly significant (p = 0.001).

This was confirmed, as the method of detection remained a highly significant variable in the survival analysis after allowing for all other factors (RHR=0.59, P <0.001).

However, there are virtually equal frequencies of balanced and unbalanced products at second metaphase, which represent highly significant differences with regard to the expected frequency of balanced cells according to the metaphase I orientations (table I) (x 2 = 10.17, P = 0.001).

Seventy-eight percent of the tumours were CD40 positive, with a highly significant association with both lower stage and lower grade ( P <0.001).