“marginally significant”

These trials have shown little therapeutic benefit to the patients enrolled[ 19 ] , with the exception of a combination of erlotinib and gemcitabine, which shows only a marginally significant benefit.[ 93 ] Therefore, identification of new molecular target(s) as well as approach for modulation of tumor microenvironment (eg, tumor stroma,[ 12 13 94 ] tumor-associated inflammation[ 65 66 ] ) is necessary for developing therapeutic strategies that enhance the effect of gemcitabine and improve patient survival.

For all three genes examined in this study, mRNA levels were significantly, inversely correlated with LI across all subjects with correlations marginally significant when aged rats alone were considered ( Table 1 ).

Interestingly, we found opposite trends in these two breast tumor subgroups: while PR up-regulated tumors displayed a significant negative correlation between miR-26b and PR mRNA expression fold changes (Figure 5C ), a marginally significant negative correlation between miR-23a and PR mRNA expression fold changes (Figure 5B ), and weak and insignificant negative correlation between miR-181a and PR mRNA expression fold changes (Figure 5A ), PR expression fold changes correlated negatively only with miR-181a expression fold changes (marginally significant) in PR down-regulated tumors (Figure 5A ).

Results There were significant or marginally significant interactions between micronutrients and blood lead levels on mean homocysteine levels.

Further analyses also showed marginally significant results in hospital-based, population or community-based studies and studies of large sample size or high expected power ( Table 2 ).

A P value < 0.05 was considered statistically significant and a value of 0.05 ≤ P < 0.1 was regarded as marginally significant.

A significance level of <0.01 rather than the usual <0.05 level indicated a highly significant result, while results with a P value between 0.01 and 0.05 were referred to as marginally significant. 3.

Given the limitations of clinical research, this was a well-controlled study with a substantial number of dogs, the dogs treated in this study are similar in age and weight to those dogs typically treated with TPLO,[ 12 ] and that the statistically insignificant (or marginally significant) differences in radiographic healing scores between the two groups were small at all time points (Tables 4 and 5 ).

These results contrast with those of Watson and colleagues [ 8 ], who found that for completely recovered patients their retrospectively measured pre-injury health state values closely matched their values 12-months after injury using the SF-6D, although they found a marginally significant difference using the AQoL.

A broad exploration was conducted, and as such, marginally significant differences should only be considered suggestive.

However, group differences in years of education and estimated current IQ were marginally significant. 3.2 Neuropsychological measures The average times of assessments were 9 and 18 weeks from the baseline, respectively (Table 2 ).

Analyses on the secondary RVP outcome measures revealed a significant main effect of DRD2 genotype, a marginally significant main effect of childhood trauma, and a significant interaction between DRD2 genotype and childhood trauma on the probability of hit in RVP ( F 2,113 = 3.674, p = .028, partial η 2 = .061; F 1,113 = 3.789, p = .054, partial η 2 = .032; F 2,113 = 4.140, p = .018, partial η 2 = .068, respectively).

Only three proteins (CPN-3, ASP-4, and VIT-6) display marginally significant higher turnover rates in daf-2 , but they lack a clear biological relationship.

Compared to the highest tertile of total drinking years, men in the lowest tertile had a marginally significant increased risk (OR 2.16, 95% CI 0.98–4.78, p for trend <0.05) and, similarly, men reporting ever abstaining compared to those who never abstained had increased prostate cancer risk (OR 1.79, 95% CI 1.05–3.03).

For the covariates, being told by a health provider that one was depressed was statistically significantly associated with current depression, suicide attempts, and suicidal ideation in the past year; after controlling for household size, having a lower annual household income was also associated with greater odds of current depression, suicide attempt (although this was marginally significant after adding the predictor variables of interest in Block 2), and suicidal ideation.

If only the interactions between two marginally significant genes are tested, some significant interactions may be missed.

However, one haplotype cluster defined by the 0.G allele of rs220168 (S47) showed a marginally significant result ( P emp = 0.0763 only for cases with SE ≤ -12 D) when tested with the Beagle program by a localized haplotype-cluster model and corrected for multiple testing by 10,000 permutations.

For example, Mogilski and colleagues [ 19 ] found no significant differences between relationship satisfaction ratings of monogamous partners and CNM primary partners, however, the difference between ratings of monogamous partners and CNM secondary partners was marginally significant, such that CNM participants reported higher relationship satisfaction with their primary partner than with their secondary partner.

Some differences were also found to be marginally significant in terms of PA participation among other motivational profiles.

graveolens EO with NA (30 μg/mL) achieved a marginally significant RF value of 1.5 in MIC reduction (0.4858 μg/mL) compared to the MIC (0.7288 μg/mL) of the EO alone.

Pairwise comparisons showed that patient survival difference was marginally significant for W-W vs.

Preoperative BMI is marginally significant, whereas age is not [ 15 ].

In contrast, the modest AUC for DPP-4 (0.648) with a marginally significant p -value (0.043) reinforces that DPP-4 is not a reliable classifier in the context of PCOS, body weight, or IR.

While the classification of CHR-P was more accurate, and highly statistically significant, for all combinations of features, classification of FEP was overall less accurate for all combinations and only statistically significant for the classifier based on exponent maps (marginally significant for the ones using combinations of parameter maps; Table 1 ).

Kruskal-Wallis test results showed that predicted capture likelihood was significantly higher at the locations of sets from 2015 NCDMF gillnet and longline surveys where each species was present, though results for Smooth Dogfish were marginally significant at an α = 0.05 significance level ( Table 6 ).