[ 65 ] reported a significant decrease in mitogen-induced T cell proliferation along with an increase in lysozyme concentrations and a marginally significant increase in monocyte phagocytosis, along with a marginally significant decrease in the numbers of CD4+ T lymphocytes in T. truncatus that had antibody titers ≥ 1:8 against morbillivirus, suggestive of previous exposure to the virus, compared to animals with lower or no titers.
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136 After 16 weeks of treatment, there were no differences in the primary outcome measures assessing episodic and spatial memory between the memantine group and the placebo controls; however, there was a marginally significant outcome in one secondary memory measurement. 136 Results of a small trial with the green tea component, EGCG, were recently reported. 84 Fifteen participants aged 14–29 years were treated with EGCG for 3 months.
We only observed marginally significant associations with BMP2 (P ARTP = 0.083), BMPR1A (P ARTP = 0.053), BMPR1B (P ARTP = 0.069) for colon cancer survival.
Changes in TBW % BM were marginally significant between infected and control bats, but not when corrected for multiple comparisons (Tables 2 and 3 ).
Regarding tomographic outcome variables, polymorphisms at the 10q26 locus showed an association with mean CSMT change at month 12, which was marginally significant after correction.
microsora and the unknown ascomycete showed a marginally significant response to the tree diversity of the local neighbourhood (Table 3 ).
There was also a marginally significant gender by service interaction for speech and mental health, with parents of girls with speech or mental health services having lower parental distress than those without these services (at the trend level only).
Results provided quantitative evidence of a significant difference in vegetation density due to thinning and burning, and a marginally significant difference in vegetation patchiness due to grazing.
The ANOVA for civic engagement behaviors indicated a significant increase in participants’ exercise of rights and a marginally significant increase in civic engagement activities and behaviors.
SETDB1 appeared of lesser importance in this regard displaying a marginally significant favorable effect in univariate analysis in the entire cohort.
An EDIC > 3 Gy was marginally significant in the multivariate analysis (supplementary material).
Interestingly, however, while the aforementioned study (Pagnoni and Cekic, 2007 ) exposed a marginally significant negative correlation in the control group ( r = −0.54) and a non-significant positive correlation in the meditation group ( r = 0.006), our study revealed significant negative correlations between age and gray matter both in controls ( r = −0.77) and in meditators ( r = −0.58).
After accounting for this major disruption, the internet-based model itself was associated with a marginally significant immediate change, suggesting its effect was likely obscured by the pandemic’s overpowering impact.
The absence of significant publication bias, as evidenced by Deeks’ funnel plot analysis ( p = 0.08), further strengthens the validity of our conclusions, though the marginally significant p-value necessitates cautious interpretation regarding potential small-study effects.
Discussion We demonstrated a statistically significant effect of PM 2.5 on a reduction in HRV measured by HF, pNN10, and pNN20, and in SDNN and rMSSD that showed a marginally significant effect.
For all statistical tests, we defined significant as a < 0.05 and marginally significant as 0.05 < a < 0.1. 3.
Many P-values are marginally significant (0.035, 0.039, 0.042, 0.050) and would likely not survive False Discovery Rate correction.
All tests were considered significant at the α = 0.05 level, marginally significant when 0.05 < α < 0.10.
For all analyses, tests were two-tailed and P values ≤ 0.05 and 0.05–0.10 were considered statistically significant and marginally significant, respectively.
Nevertheless, we have now acknowledged in the Discussion that some findings may have arisen by chance due to multiple testing, and we recommend cautious interpretation of marginally significant results.
Though marginally significant, we found a difference between geometric mean blood lead concentrations of children whose family consumed fresh water fish and those who did not (2.85 μg/dL vs. 2.17 μg/dL, respectively; p = 0.07).
In a multiple regression model, age of home and ln(creatinine levels) were significant predictors and sampling season, time spent outside, and pet ownership were marginally significant predictors of ln(urinary PCP levels), collectively explaining 29% of the variability of PCP in urine.
This was followed by the addition, in stepwise manner, of variables that were marginally significant in bivariate analyses.
There were also marginally significant correlations between Al and Cd, and between Hg and Se.
Recent prospective phase III trials (AVAglio & RTOG 0825) were designed to prove the efficacy of TMZ based radio-chemotherapy with bevacizumab as first-line therapy but failed to show a survival benefit whereas significant and marginally significant progression-free survival benefits have been observed [ 23 , 24 ].