“may be significant”

annua seeds has re-myelinating properties, which may be significant in treating neurological disorders accompanied with loss of myelin [ 25 ].

The hyperabundance of vWF in BPD-EVs may be significant, as BPD is characterized by impaired vascular development due to vascular endothelial injury or activation, with accompanying inflammation, in both the BPD lungs and the ROP retinas [ 39 , 40 , 41 ].

Taken together, these data show that while the volume of saliva collected is relatively constant throughout the day, there may be significant differences at certain time points. 3.4 Consistency and Reproducibility of the Measurements Measurement consistency and reproducibility were assessed using ICC (ICC 1 ; ICC 2 ; ICC 3 ; and ICC 3 adjusted for age and sex), as summarised in Table 2 .

In conclusion, our findings highlight disruptions in lipid metabolism and complement pathways in the serum of SIHD and CAC_SIHD patients, suggesting that altered lipid profiles and immune dysregulation may be significant risk factors.

In this context, it may be significant that DNA cleavage by topo VI seems to be strictly dependent on ATP binding ( 35 ).

As 82.1% of all PTSD cases haven’t been characterized by the positive treatment outcomes, the study may be significant for the treatment of these patients.

Whilst such difficulties are minimal for brain scans, they may be significant in other anatomical regions wherein there may be substantial organ movement or deformation.

Measuring the impact of pharmacovigilance interventions is challenging as treatment and disease outcomes often overlap, and there may be significant time lags until clinical effects are seen with many existing studies being ecological in nature.

For both general population and organic consumption studies there may be significant heterogeneity with regard to the pesticides chosen for monitoring and the methods and LODs used.

Furthermore, it is well documented that gaps in education, income, and access to resources may be significant barriers to technology adoption in LMICs [ 27 ].

Indeed, temperature and moisture conditions near the time of planting, even at a very fine temporal resolution (e.g., daily; O’Connor et al., 2020 ), may be significant for subsequent recovery (Maier et al., 2001 ; Shinneman & McIlroy, 2016 ; Shriver et al., 2018 ; Ziegenhagen & Miller, 2009 ).

This finding suggests that both canonical and noncanonical NF-κB signaling is involved in response to anti-PD-1 therapy, and that there may be significant interplay between these two pathways.

This important observation suggests that there may be significant merits in systematically combining AF2 modelling information with sequence data when estimating phylogenetic tree reliability.

It is suggested that this region may be significant for Ca 2+ -induced polymerization [ 57 ].

However, the distortion of the P300 potentials induced by flashing stimulus images may be significant since the P300 potentials mainly appear in the parietal and central areas (Iturrate et al., 2009 ).

There are numerous unexplored biological contexts where the role of DEXI may be significant, and one such setting could be EBV infection.

The potential amount of inorganic N released to the soil by a typical colony of 20,000 bees foraging in an area similar to that of the experimental cages (3.24 m 2 ) was estimated at 0.62 to 0.74 g N m −2 month −1 which may be significant at a community scale in terms of soil microbial activity and plant growth.

The fact that the PFC matures last and that myelination is not complete until late adolescence may be significant, as the timing coincides with the typical onset of symptoms in schizophrenia.

The increasing degree of clustering observed with scale suggests that environmental filtering may be significant across scales but with potentially different forces at work, such as local floral resources influencing assembly processes, regional radiations, dispersal to the New World, etc.

While there may be significant barriers to Internet access for certain demographic groups, such as those above age 65 and those with lower education and income levels (Rainie 2010 ), our study indicates that once members of these demographic groups do gain access to the Internet, the potential for the Internet to close socio-economic gaps and racial divides is high.

Even for the same plant antioxidant, there may be significant differences in absorption, metabolism, and excretion rates among individuals, thereby affecting therapeutic efficacy [ 131 ].

The activation/inactivation curves in Figure 1E show differences in both activation and inactivation at physiologically relevant membrane voltages, which may be significant even though the V1/2 and slope factors are roughly similar.

Noteworthy, although there may be significant relationships between medical institutional trust, communication, and nurses’ expectations [ 22 , 24 ], the patterns of these relationships may vary across major-risk environments [ 26 ].

2 Structural differences between polymorphs may be significant or very subtle.

This latter point may be significant in the selection of therapeutic chemotypes, if any, prior to scientific assessment for safety and efficacy.