This phenotype may be significant as MLS-2 is predicted to have a high scoring eh1 motif [12] , and it suggests that unc-37(e262) may affect the activity of both MLS-1 and MLS-2 in specifying cell fates in the M lineage.
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In the literature
Therefore, cell cycle distribution may be significant in developing potential chemotherapy drugs.
Safety Concerns: When machinery breaks down, there may be significant safety hazards [ 80 ] for people, repair staff, and operators.
In the actual process, the system will operate alternately under different working conditions, and due to the different operating states of the system, there may be significant differences in the monitoring data of the system.
This type of results indicates that there may be significant shortcomings in our current models of how duplicated genes differentiate, evolve new functions and are preserved in the genomes (see discussion in [ 27 ]).
95 , 96 Even with the use of protons, common radiation-associated toxicities such as fatigue and cytopenias can still occur and may be significant in a heavily pretreated or elderly patient.
Even when insurance coverage exists, there may be significant out-of-pocket costs and access issues.
This finding may be significant in clinical practice, if proven by further research, those in younger age groups, considering their higher rates of metastasis to the brain, may require specific metastasis work-ups such as brain MRI and brain CT to rule-out metastasis to the brain which may be different from older individuals.
Although past SA is a strong risk-factor for future SA, there may be significant neurobiological differences among those who engage in SA prospectively and those who die by suicide as compared to those with history of SA.
The financial and social consequences of such errors may be significant [ 1 ].
14 These results indicate that Zwint may be significant in cancer and may be a potential target for cancer diagnosis and treatment.
These findings suggest that the regulatory mechanism of ceRNA may be significant in the upregulation of Acin1 and possibly contribute to its fine-tuned regulation.
This information may be significant for both ecological and agricultural research.
In an emergency, the pilot should be aware that during abrupt maneuvers, the attitude error may be significant, which is unfortunately a typical characteristic of solutions utilizing low-cost MEMS sensors.
17 , 19 The distinction between aortic and peripheral artery pressures may be significant due to the phenomenon of SP amplification 18 , 32 : due to the difference in elasticity between aortic and brachial arteries, the SP measured at the brachial artery is amplified from reflected waves and can thus introduce errors when applying centrally derived formulas to peripheral measurements. 19 Routine measurements of blood pressure are not conducted centrally, therefore it is important to validate and determine the optimal MAP formula at a peripheral artery for comparable results.
Therefore, this article speculates that there may be significant heterogeneity in the economic development level of the impact of Huimin Insurance on the urban-rural consumption gap.
One limitation of the study is that patients were recruited at various stages of the disease process therefore there may be significant variation in time frame for weight loss.
Notably, there may be significant differences between MSC-mediated Nrf2 activation and pharmacological activation using bardoxolone methyl.
There may be significant differences of gestational fetal KCs at different ages.
Though FP tumors were elevated in several amino acids, dietary shifts in arginine may be significant.
Therefore, there may be significant differences in ICAM and VCAM in patients with and without breast cancer (regardless of obesity and metabolic syndrome) and this should be investigated in future studies.
It may be significant that the effects are opposite for wins and losses – perhaps this reflects asymmetric processing of outcomes that are noisy but not volatile [ 53 ].
Although a 10-fold decrease may be significant in terms of expression of some genes, in repeated attempts, the fold changes at the mRNA level differed with the batch of base medium used, so no definitive in vitro culture conditions that reliably mimic the midgut of the unfed tick were identified with regard to P66 production.
HDI reported for a given country represents a standardised measure of the social and economic development of that country; however, there may be significant intra-country variations, especially in large medium-HDI countries such as India, where there are notable differences between rural and urban regions.
Also, environmental and physical causes of throat discomfort affected respondents throughout the year and the ongoing and cumulative impact of such suffering may be significant.