Barely Significant
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may be significant

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In the literature

This finding may be significant in clinical practice, if proven by further research, those in younger age groups, considering their higher rates of metastasis to the brain, may require specific metastasis work-ups such as brain MRI and brain CT to rule-out metastasis to the brain which may be different from older individuals.
17 , 19 The distinction between aortic and peripheral artery pressures may be significant due to the phenomenon of SP amplification 18 , 32 : due to the difference in elasticity between aortic and brachial arteries, the SP measured at the brachial artery is amplified from reflected waves and can thus introduce errors when applying centrally derived formulas to peripheral measurements. 19 Routine measurements of blood pressure are not conducted centrally, therefore it is important to validate and determine the optimal MAP formula at a peripheral artery for comparable results.
Although a 10-fold decrease may be significant in terms of expression of some genes, in repeated attempts, the fold changes at the mRNA level differed with the batch of base medium used, so no definitive in vitro culture conditions that reliably mimic the midgut of the unfed tick were identified with regard to P66 production.