“may be significant”

The Role of Breathing Pattern Disorders and Exercise-Induced Laryngeal Obstruction (EILO) Breathlessness, particularly on exertion, may be due to exercise-induced bronchoconstriction (EIB), but even in known asthmatics, an abnormal breathing pattern and/or EILO may be significant contributors.

As described earlier, we were able to select bound DNA in solution using all of the DMRT proteins except DMRT6, but there were differences in the behavior of several proteins in the gel mobility shift assay that may be significant.

Additionally, the development of personalized treatment strategies is essential, as there may be significant variations in the gut microbiota composition and response among individuals.

5 Despite their evolution and improvement (integration of advancing parameters such as age, sex, and immunity), 6 , 7 animal models still suffer from interspecies differences, which may be significant in translating data into human physiology. 8 Therefore, a gap remains in clinical trials of drugs for TBI.

Combination therapy generated higher fractions of both KLRG1+ CD8+ and CD4+ effector T-cells in the context of FVAX versus GVAX which may be significant in explaining the lack of cooperativity observed with GVAX ( Figure S7 ).

Apart from CO 2 , other carbon species may be significant.

Previous morphological study that revealed variation in the structure of the male genitalia within and among populations of this species suggested that there may be significant population-level genetic variation.

<8 cm H 2 O), disturbing partner’s sleep, and being moderately to extremely sleepy at baseline may be significant predictors of improvement in self-reported sleepiness during PAP therapy (Figure E1).

The upper confidence interval of our blood donor viremia estimate of 1 in 1,667 suggests that the risk of collecting a viremic donation may be significant and supports the current precautionary strategy of restricting “at-risk” donors to donating plasma for fractionation only.

These limitations will have to be borne in mind during the use of ASL MRI in patients with chronic kidney disease given there may be significant alterations in transit time both between individuals and within individuals over time.

Fast PET/CT scanning may be significant for pediatric patient (decreasing anesthesia or sedation time) or for sick patients who cannot lay still for prolonged periods of time.

Intriguingly, SUMO-1 is conjugated to K6 and K9 equivalently in the absence of other modifications, whereas phosphomimetic substitutions of S13 and S16 appear to block SUMO modification on K9 or promote SUMO-1 modification on K6, which may be significant to regulation of other HTT modifications, such as K9 acetylation.

Discussion The aim of the study was to identify copy number variants (CNVs) in autism-related genes and in candidate genes that may be significant in the etiology of autism.

produce butyrate, their role in promoting enterocyte turnover and preserving tight barrier junctions may be significant.

Analytical methods Propensity score matching (PSM) Since students’ preferences for internet usage are not entirely random and are likely influenced by their behavioral characteristics and family environments, there may be significant differences in control variables between students with high and low internet usage preferences.

Our finding may be significant as defects in fatty acid oxidation occur in response to chronic ethanol consumption [33] .

Subgroup analysis provided evidence that the beneficial effect may be significant among women, but less robust among men.

This mechanism may be significant for rib fracture analgesia, since tissue distribution due to trauma can facilitate spread to muscles and deeper planes, such as the intercostal space [ 26 ].

Through the analysis of ARGs in giant panda feces, it was found that a variety of antibiotic types were present, indicating that the source of resistance is complex, and that environmental pollution in captive giant pandas may be significant [ 12 ].

The described biological processes may be significant factors in larval stress following high temperature exposure.

The consequence of overdispersion may be significant—the analyst believes they have more information than there is in the data, and this belief leads to overconfidence in the assessment of thresholds and the structure governing them.

The gas trapped in the amorphous silica particles during their formation process and for the ones with encapsulated drug may be significant in comparison to the m-SiO 2 particles which have an organised large porous network (average pore size 2.7 nm) where adsorbed gas or drug can leak uncontrollably.

The lymphocyte apoptosis which accompanies neutrophil apoptosis may be significant in pathogenesis of IMD by disrupting the T-B lymphocyte activation and interaction required for generation of bactericidal antibody. 6 7 We have obtained preliminary confirmation of virus-associated lymphocyte apoptosis using flow cytometric assessment of annexin-V binding 30 in IM, which showed enhanced binding by CD4, CD19, and especially CD8, but not natural killer lymphocytes (Smith H, unpublished).

Notably, both fat amplitude and connective tissue width were significantly and inversely-related to all three outcome conditions; this suggests that an increase in fat tissue, concomitant with a wider connective tissue distribution, may be significant protective factors against cardiovascular pathophysiology.

Potential future work will consider GI tract exposure to NPs cleared from the tracheobronchial region because it may be significant for aggregated NPs at heavy-exercise breathing conditions.