Barely Significant
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may be significant

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In the literature

We chose an analogous time in the previous year instead of the time immediately preceding the COVID-19 pandemic because there may be significant variation on seeking treatment over the course of the year, especially with respect to seasonal weather changes and seasonal travel of patients (especially elderly, retired patients) between regions of the United States.
Additional clinicopathological investigation for familial AD‐related mutation carriers may be significant to explore the association between familial AD and suicide. amyloid‐β autopsy familial Alzheimer's disease immunohistochemistry neurofibrillary tangle presenilin 1 suicide JSPS KAKENHI JP21H03211 to YH JP23H03759 to NN Microscopically, in Case 1, the abundant amyloid plaque, including the neuritic plaque, was noted in the whole brain.