“may be significant”

Thus, the progressive accumulation of uremic metabolites, especially ones that may be poorly filtered by conventional dialysis membranes, may be significant contributors to the progressive decline of mitochondrial health observed in patients with CKD.

Fourth, the study was retrospective with analysis of observational data; thus, the diversity of the two groups of patients may be significant and hard to control.

The processes observed by the Williams group may be significant for ion formation in previously disclosed ion sources, including ESI and ambient ion sources.

Self- direction is an important aspect of clinical attachments, as there may be significant time spent apart from the team.

Since the number of people in the vaccinated group was significantly smaller than that in the unvaccinated group, there may be significant differences in other key characteristics, making the comparison results between the two groups inaccurate or subject to selection bias.

Thus, like in larval transmission, it may be significant for YFV transmission or persistence in enzootic foci in sylvan environments.

The calculated rate constants and product branching ratios for the HNCO + C 3 H 3 reaction show that the reaction may be significant only in the high-temperature region, at the temperature above 1500 K under any pressure.

The potential efficacy of low doses (25 and 50 ng/mL) in reducing factors of the NF-κB and MAPK pathways, similar to COX-2 and iNOS, may be significant for inflammation treatment.

Other studies have suggested that male sex and cholesterol levels may be significant risk factors for high vascular calcification in young adults ( 20 - 22 ), while others have proposed that psychological factors and emotional stresses may also play a role ( 23 , 24 ).

Lateral diffusion and vesicle tumbling are not expected to influence the line shape because of the large size and low curvature of MLVs, 19 , 23 but if FBTA disrupts the lipid bilayer and promotes the formation of smaller vesicles and/or non-bilayer structures then contributions of these modes of motion may be significant.

Because other iAs exposure routes, particularly diet, may be significant when concentrations of iAs in drinking water are low ( Lindberg et al. 2006 ), we performed analyses that excluded those with a sum of iAs metabolites in urine < 2.5 μg/L (in line with Lindberg et al. 2006 ).

It may be significant that ME7‐associated increases in IBA‐1, cathepsin D, and CD68 expression in white matter (cc and internal capsule) were mitigated in IFNAR1 −/− mice.

[ 4 , 5 ] These symptoms, regarded as components of dry eye, range in severity, but the effects on quality of life may be significant.

As in resolvase there may be significant conformation changes that occur with activation of recombination ( 34 , 37 ).

Particularly concerning are families because the increased poverty rate is more prevalent among them compared with the general population, and because children’s consequences may be significant [ 4 ].

It is of particular note that all patients enrolled were from Thailand which may be significant in regard to their conclusions.

Participation in a consistent group that shares similar experiences and challenges in everyday life, is subject to reliable rules and a fixed structure, and promotes mutual respect, joint development of solutions to problems, and purposeful interactions with each other may be significant here.

P value may be significant but the difference between two groups for endpoints may not be as large to have some clinical significance.

Therefore, pressure is higher at the entrance of the lesion, and the effect of the entrance region is always to increase the average friction factor for the entire lesion which may be significant for shorter segments.

Although detailed epidemiological data on IDA in CD are limited, recent studies suggest that IDA may be significant in both CD children [ 10 , 11 ] and adults [ 12 ].

In stabilising the slip, gold standard treatments stop growth and involve premature physeal closure, which prevents the remodelling of the acquired deformity and creates a leg length discrepancy that may be significant in younger patients.

The resources required to respond to prolonged and severe stress may be significant.

Previous studies have shown that distinguishing specific subtypes of IA is also a valuable research perspective, as predisposition factors may vary by IA types (e.g., there may be significant gender differences between online game addiction and social media addiction [ 75 , 76 ].

Indeed, the POAG patients studied had reduced total omega-3 long-chain polyunsaturated fatty acids, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) fatty acids.[ 7 ] These findings may be significant as EPA and DHA could modulate impaired systemic microcirculation, ocular blood flow, and positively impact optic neuropathy, which are the main physiological changes associated with glaucoma.[ 21 ] Numerous studies have assessed FABP2 gene variants and their association with insulin resistance and type 2 diabetes mellitus.[ 7 ] This is the first time we are reporting this gene polymorphism in POAG cases.

This methodological drawback may be significant particularly in clinical practice as threshold changes are commonly encountered in disease states such as stroke [ 16 ].