Spirometry is required to make the diagnosis, however there may be significant lung pathology (e.g., emphysema) in the absence of airflow limitation that needs further evaluation.
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“may be significant”
In the literature
It may be significant that Asp-387 (or glutamate) is almost invariant in the ETS recognition helix, with only class III proteins displaying a substitution to glutamine ( 32 ).
M06L 56 , 57 is a meta-GGA (Generalized Gradient Approximation) functional that includes dispersive interactions, which may be significant for the adsorption and chemical reactions within zeolitic materials.
Although the amount of physical activity is less than the recommended 10 min bout [ 20 ], the volume may be significant when accumulated over the long run as found in one prospective study where by men had a 29% decrease in stroke risk associated with stair use [ 10 ].
As the mediating effect of peer influence spanned both adopters and non-adopters and acted as both a barrier and facilitator to adoption, we found this to be a key factor that may be significant to other ICS programs.
Miscellaneous lung diseases Platelets may be significant elements in the pathogenesis of several pulmonary diseases, including some that are not obviously vascular diseases.
Furthermore, the correlation coefficient may be significant or insignificant, which is determined by the P value.
However, evidence from Latin America is still scarce, and family factors may be significant in Latin America.
However, it may be significant that only EcArgR and VvArgR, which appear to lack α4, both have an Arg residue in α5.
Nationally, there may be significant overlap between students who take AP and dual enrollment credit; no current study can substantiate such a claim, however ( Ryu et al., 2024 ).
16 Removal of glucose during a dialysis session may be significant enough to require a different dose of basal insulin on dialysis and non-dialysis days. 17 Dialysis therapy also corrects hyperkalemia and acidosis associated with hyperglycemia.
As part of the intervention, actigraph was also used to compare pre- and post-mean sleep parameters (SE%, TST, SOL, and NWAK) scores to identify changes in sleep/wake patterns in the ICG and evaluated the effectiveness of the intervention, as conducted in previous studies.[ 32 , 38 , 39 ] Although, as a whole, the findings could not observe significant differences, these are still need to be interpreted with caution as there may be significant discrepancies for some individuals, but was not observed in this study.
Shulman and colleagues (2016) identify several refinements of the dual-systems model that we endorse, especially the prediction that social contexts (especially peer contexts) may be significant moderators of many developmental effects.
Our findings have implications for current CFPE management strategies, supporting reassessment of existing antimicrobial treatment regimens, as antimicrobial resistance by pathogens and other members of the microbiota may be significant contributing factors. status released display-pdf yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Received 2015 Jul 27; Accepted 2015 Sep 22; Issue date 2016 May.
In a similar manner stabilization of ARE-bound protein complexes by HBZ may be significant to the mechanism by which HBZ activates transcription from AREs.
In this context, it may be significant that both Irgb6 and Irgb10 can load, albeit inefficiently, onto T. gondii vacuoles in the absence of other IRG proteins ( Hunn et al. , 2008 , Fig. 7 and J.P.
In such cases, the role of superimposed myocarditis in the course of the disease may be significant.
The joint behavior of functionally or spatially related genes may be significant, whereas the activity of individual genes may not.
Moreover, this feature is shared with some plant species [ 164 ] and may be significant in terms of ribosome biogenesis and cellular efficiency.
Given the fact that ChrY is a small, often mutated chromosome in cancer [ 58 ] several identified ChrY-encoded antigenic regions whose loss or alteration may be significant to this process due to the potential to induce camouflaging.
We speculated that this evidence may be significant since ASD individuals, unlike PWS individuals, do not have hypothalamic syndrome, which can per se cause temperature fluctuations and sensory abnormalities.
Clinical investigations have revealed that the potential of AAT is limited when used as a single therapeutic modality, but the therapeutic benefit may be significant when AAT is used in combination with conventional chemotherapy or radiation therapy [3] .
Despite the advantages, nMS is not used to the extent of the more common biophysical methods, including those where there may be significant challenges such as X-ray crystallography, that requires proteins suitable for crystallisation, or NMR, where proteins are commonly isotopically labelled and high fragment stock concentrations are needed, that can frequently meet with insufficient solubility leaving many fragments unsuitable.
Ocular use of these agents has been associated with small increase in risk of systemic thromboembolic events, which may be significant in a few cases.[ 24 ] Moreover, intraocular injections of biosimilars are capable of inciting immunologic reactions.
Thus, the AURKA SNPs may be significant predictors of UCC occurrence and reliable biomarkers of disease progression and metastasis in patients with UCC.