“may be significant”

There is no established treatment for GBM recurrence, thus the results of the present study may be significant in treatment decision making for patients and may contribute to the improvement of patients' outcomes.

The VA before treatment, the disruption extent of EZ, and age may be significant factors affecting the VA with complete resolution of MO.

10 , 11 , 12 The method for inducing cardiac arrest may be significant to the neurological outcome.

This suggests that regions in the hypothalamus are more susceptible to damage by goldthioglucose than other brain areas. The findings that low levels of blood goldthioglucose concentration produced small focal lesions in the ventromedial area whereas higher levels of blood goldthioglucose concentration produced broader lesions of similar density suggest that there may be significant differences in the metabolism and/or supply of goldthioglucose to various regions of the ventromedial hypothalamic area.

Therefore, our finding that the concomitant use of an SGLT2i does not suppress the therapeutic effects of tirzepatide may be significant.

Thus, the appropriateness of empiric therapy and underlying severity of illness may be significant factors for mortality in nosocomial pneumonia caused by MRSA, rather than the specific sequence types.

Bioinformatics analysis suggests that the HIF-1, Jak-STAT, and TGFβ signaling pathways may be significant routes through which C3AR1 participates in preeclampsia.

This may be significant in case of pathophysiological findings such as the toxic effects of bile acids [ 62 ] or emergence of atrial fibrillation [ 63 ].

The role of the endotoxin in clinical disease is unclear, although it may be significant in septicaemic cases.

From an animal welfare perspective, the difference in reciprocation between equid→human (64.2%) and human→equid (14.5%) interactions may be significant.

These or other changes in environment and routine may be significant enough to alter animal physiology as compared to their original, prerelocation levels.

This may be significant because in experimentally grown SLs, thicknesses of individual blocks vary (from 5 to 13 28 ) with an increment of two atomic layers, which was attributed to a local change in stoichiometry in terms of the number of GeTe BLs.

The approach is also applicable with single-species motif scores (although this led to poorer performance in our setting), which may be significant for discovery of CRMs that are not as well conserved [52] .

Additionally, there may be significant fat volume variation that is genetically driven but not outside expected ranges for each depot and as such may not demonstrate the same relationships as a true pathologic increase in central adiposity.

This means that there may be significant gaps in the data, particularly from countries that are not members of the WHO’s PIDM.

Thus, the enrichment of potential urologic pathogens in the renal function decline group may be significant.

Additional clinicopathological investigation for familial AD‐related mutation carriers may be significant to explore the association between familial AD and suicide. amyloid‐β autopsy familial Alzheimer's disease immunohistochemistry neurofibrillary tangle presenilin 1 suicide JSPS KAKENHI JP21H03211 to YH JP23H03759 to NN Microscopically, in Case 1, the abundant amyloid plaque, including the neuritic plaque, was noted in the whole brain.

In addition, interactions of nonnucleoside drug combinations on lipid metabolism may be significant in a setting where stavudine was most often given with nevirapine.

Thus, our results imply that deacetylation and dimethylation of H3K9 may cause the formation of facultative heterochromatin at specific gene promoter regions, which may be significant to MSC osteogenic differentiation through some silencing mechanisms.

It may be significant that there are no donor dendritic cells to serve as stimulators or targets in these tumor grafts.

Based on inverse proportions of eosinophils, macrophage numbers also appear to be higher in the granulomas of naturally-infected wild water rats ( Nectomys squamipes ) than in chronic granulomas of experimentally-infected mice ( 133 ), indicating that there may be significant differences between experimental and natural granuloma formation that must be taken into account.

The information gathered could be useful for designers and marketers to guide the packaging design for fish products in the Spanish market, although care is required if the results obtained are extrapolated to other countries and products, as there may be significant differences among consumers’ preferences from different regions and cultures.

While some of these findings may be significant to the setting in Sierra Leone and the Ebola vaccine trials or may be influenced by some of the limitations in this study, it is hoped that these Four R’s could facilitate CE in other settings and strengthen disease preparedness activities.

2 It has been reported that in addition to critical illness, there may be significant effects on appetite, conscious state, and direct gastrointestinal effects resulting in nausea, vomiting, diarrhoea, and feeding intolerance.

This may be significant for the operational interpretation of results, considering that African Anopheles typically bite at night.