Barely Significant
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may be significant

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In the literature

This is performed via a thoracotomy and whilst high closure rates and low mortality are reported there may be significant morbidity.
Patent arterial duct.
Orphanet J Rare Dis · 2009 · PMC2716300
It is tempting to speculate whether failure of CX 3 CR1 deficient cells to tubulate, or initiate differentiation into mural smooth muscle-like cells or impairment of extracellular matrix production may be significant contributors to increased microvessel porosity to blood and solutes in vivo thus providing a mechanism underlying the leaky MV phenotype.
1989 ) and for this it may be significant that the spectral sensitivity of the main retinular cells R1-R7 covers the wavelength range below 550 nm where sky-ground contrast is highest (Fig. 4 ) and where intensity variations in the sky (blue sky and clouds) and on the ground (specular reflections and shadows) are smallest (Fig. 5 ).
Views from 'crabworld': the spatial distribution of light in a tropical mudflat.
J Comp Physiol A Neuroethol Sens Neural Behav Physiol · 2023 · PMC10643439