Barely Significant
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may be significant

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In the literature

Notably, the identification of OTUs belonging to Sphingomonas (OTU0054) and Lachnospiraceae (OTU0318) as differentially abundant between Dmbt1 −/− and Dmbt1 + / + and between precancer and OSCC diagnoses by both LSVCMM and fPCA analyses suggests that these OTUs may be significant for OSCC development and possibly regulated in some way by DMBT1.
It is possible that age-related variables, as well as differing blood alcohol concentrations, may be significant contributing factors to the differential findings in ceramide profiles, as the acute ethanol doses administered by injection [ 21 ] or intubation [ 22 ] in the former studies would be expected to result in higher BACs (particularly in neonatal rodents) than those previously reported via voluntary drinking by adult P rats in the intermittent access paradigm (11–63 mg% [ 27 ]).
However, this does not mitigate the importance of inquiry into health promoters’ understandings of these concepts as even in Norway there may be significant “lifestyle drift” in health promoters’ and municipal authorities’ actual activities. 10 It should also be noted that the Ontario study involved medical officers of health and senior/key public health staff while the Hagen et al. study collected data from PHCs who were often part-time and in lower-level positions.